Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(93 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(64 produtos)
- Receptor CGRP(52 produtos)
- Canais de Cálcio(496 produtos)
- Canal de cloreto(49 produtos)
- Receptor GABA(336 produtos)
- Transportador de monoamina(23 produtos)
- Transportador de monocarboxilato(17 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(8 produtos)
- OAT(27 produtos)
- OCT(7 produtos)
- P-gp(53 produtos)
- Canal de Potássio(277 produtos)
- Bomba de prótons(39 produtos)
- SGLT(30 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(93 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2290 produtos de "Transportador de Membranas/Canal Iónico"
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ML213
CAS:<p>ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,</p>Fórmula:C17H23NOPureza:>99.99%Cor e Forma:SolidPeso molecular:257.37YHO-13351
CAS:YHO-13351 is an ABCG2 inhibitor that induces sensitization of cancer stem cells/initiating-like side population cells to irinotecan.Fórmula:C27H37N3O7S2Pureza:97.88%Cor e Forma:SolidPeso molecular:579.73Lomerizine
CAS:<p>Lomerizine, a blocker of diphenylmethylpiperazine Ca2+ channel, is used to prevent migraines.</p>Fórmula:C27H30F2N2O3Cor e Forma:SolidPeso molecular:468.54Pico145
CAS:<p>Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.</p>Fórmula:C23H20ClF3N4O5Pureza:99.06%Cor e Forma:SolidPeso molecular:524.88p-Hydroxybenzaldehyde
CAS:1.Fórmula:C7H6O2Pureza:99.05% - 99.86%Cor e Forma:SolidPeso molecular:122.12Selinexor (KPT-330)
CAS:<p>Selinexor (KPT-330) is an orally available, small molecule inhibitor of CRM1 (exportin 1 or XPO1), with potential antineoplastic activity.</p>Fórmula:C17H11F6N7OPureza:98% - 99.97%Cor e Forma:SolidPeso molecular:443.31TRAM-34
CAS:<p>TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.</p>Fórmula:C22H17ClN2Pureza:99.01% - 99.91%Cor e Forma:SolidPeso molecular:344.84BI 01383298
CAS:<p>BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).</p>Fórmula:C19H19Cl2FN2O3SPureza:99.71%Cor e Forma:SolidPeso molecular:445.34Unifiram
CAS:<p>Unifiram boosts cognition, enhances rat hippocampal signals (EC50=27 nM), and ups ACh in rat cortex.</p>Fórmula:C13H15FN2O3SPureza:99.9%Cor e Forma:SolidPeso molecular:298.33TRPM4-IN-1
CAS:<p>TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.</p>Fórmula:C15H11Cl2NO4Pureza:97.22%Cor e Forma:SolidPeso molecular:340.16GLPG1837
CAS:<p>GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.</p>Fórmula:C16H20N4O3SPureza:99.64% - 99.91%Cor e Forma:SolidPeso molecular:348.42Caroverine hydrochloride
CAS:Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.Fórmula:C22H28ClN3O2Pureza:98.37% - 98.75%Cor e Forma:SolidPeso molecular:401.9VU590 HCl
CAS:<p>VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM).</p>Fórmula:C24H34Cl2N4O7Cor e Forma:SolidPeso molecular:561.457Tricaine methanesulfonate
CAS:<p>Tricaine methanesulfonate (TMS/MS-222) is an anesthetic used in hatcheries and studies to immobilize fish for marking, transport, and invasive procedures.</p>Fórmula:C10H15NO5SPureza:99.259% - 99.86%Cor e Forma:White PowderPeso molecular:261.30CTP disodium dihydrate
CAS:<p>CTP disodium dihydrate is an agonist of P2X4 purinergic receptor</p>Fórmula:C9H18N3Na2O16P3Pureza:98.51%Cor e Forma:White Crystalline PowderPeso molecular:563.15Methyl homoveratrate
CAS:<p>Methyl homoveratrate, a McN5691 (RWJ-26240) metabolite detected in vivo in plasma, urine, and fecal extracts, functions as a voltage-sensitive calcium channel</p>Fórmula:C11H14O4Pureza:99.48%Cor e Forma:SolidPeso molecular:210.23Quinine hydrobromide
CAS:<p>Quinidine: oral, selective P450db inhibitor, K+ channel blocker (IC50=19.9μM), antiarrhythmic, used in malaria research.</p>Fórmula:C20H25BrN2O2Cor e Forma:SolidPeso molecular:405.336SSD114 HCl
CAS:<p>SSD114 is a novel GABAB receptor positive allosteric modulator.</p>Fórmula:C18H21ClF3N3OPureza:99.03% - 99.95%Cor e Forma:SolidPeso molecular:387.83BzATP triethylammonium salt
CAS:<p>BzATP triethylammonium salt is a P2X7 receptor agonist.</p>Fórmula:C30H39N6O15P3Pureza:95% - 99.57%Cor e Forma:SolidPeso molecular:816.59MK6-83
CAS:<p>MK6-83 is the transient receptor potential channel ML3 agonist.</p>Fórmula:C16H20N2O2S2Pureza:99.5%Cor e Forma:SolidPeso molecular:336.47ICA-121431
CAS:<p>ICA-121431: a potent Nav1.7 inhibitor (IC50=19 nM for rat), minimal effect on human Nav1.5/Nav1.7.</p>Fórmula:C23H19N3O3S2Pureza:98.06%Cor e Forma:SolidPeso molecular:449.55Sodium ionophore III
CAS:<p>Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.</p>Fórmula:C34H52N2O4Pureza:99.51% - 99.78%Cor e Forma:SolidPeso molecular:552.79Vonoprazan
CAS:<p>Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and</p>Fórmula:C17H16FN3O2SPureza:99.87% - 99.92%Cor e Forma:SolidPeso molecular:345.39Eniporide hydrochloride
CAS:<p>Eniporide hydrochloride (EMD-96785 hydrochloride) serves as a robust inhibitor of the sodium/hydrogen (Na+/H+) exchange process.</p>Fórmula:C14H17ClN4O3SCor e Forma:SolidPeso molecular:356.83Esomeprazole hemistrontium
CAS:<p>Esomeprazole hemistrontium, potent oral proton pump inhibitor, reduces gastric acid by blocking H+, K+-ATPase.</p>Fórmula:C34H36N6O6S2SrCor e Forma:SolidPeso molecular:776.44O4I1
CAS:<p>O4I1 is an effective Oct3/4 inducer.</p>Fórmula:C16H15NO2Pureza:96.25% - 99.47%Cor e Forma:SolidPeso molecular:253.39-Phenanthrol
CAS:<p>9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.</p>Fórmula:C14H10OPureza:98.48%Cor e Forma:SolidPeso molecular:194.23Ononetin
CAS:<p>Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).</p>Fórmula:C15H14O4Pureza:98.06%Cor e Forma:SolidPeso molecular:258.27Neramexane HCl
CAS:PAC is a cyclic amine used as a chiral auxiliary in various asymmetric syntheses.Fórmula:C11H24ClNPureza:95.00%Cor e Forma:SolidPeso molecular:205.768NPPB
CAS:<p>NPPB is a chloride channel blocker with IC50 of 80 nM .</p>Fórmula:C16H16N2O4Pureza:99.95%Cor e Forma:Light Yellow To Yellow SolidPeso molecular:300.31Ivacaftor
CAS:<p>Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,</p>Fórmula:C24H28N2O3Pureza:99% - 99.98%Cor e Forma:SolidPeso molecular:392.49Tiludronate
CAS:<p>Tiludronate, an oral bisphosphonate, treats metabolic bone disorders and inhibits osteoclasts.</p>Fórmula:C7H9ClO6P2SCor e Forma:SolidPeso molecular:318.61ML133 hydrochloride
CAS:<p>ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.</p>Fórmula:C19H19NO·HClPureza:99.48%Cor e Forma:SolidPeso molecular:313.82Selamectin
CAS:<p>Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in</p>Fórmula:C43H63NO11Pureza:99.84%Cor e Forma:SolidPeso molecular:769.96PF-4840154
CAS:<p>PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception in mice.</p>Fórmula:C26H38N6O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:466.62Myomodulin acetate(110570-93-9 free base)
<p>Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.</p>Fórmula:C38H71N11O10S2Pureza:99.24%Cor e Forma:SolidPeso molecular:906.17Esomeprazole potassium salt
CAS:<p>Esomeprazole potassium, a potent oral proton pump inhibitor, curbs acid secretion in stomach cells, aiding GERD research.</p>Fórmula:C17H18KN3O3SCor e Forma:SolidPeso molecular:383.51Flecainide acetate
CAS:<p>Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).</p>Fórmula:C19H24F6N2O5Pureza:99.42%Cor e Forma:SolidPeso molecular:474.39NS6180
CAS:<p>NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.</p>Fórmula:C16H12F3NOSPureza:99.83% - ≥95%Cor e Forma:SolidPeso molecular:323.33Flecainide hydrochloride
CAS:<p>Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.</p>Fórmula:C17H21ClF6N2O3Pureza:97.79%Cor e Forma:SolidPeso molecular:450.81Rbin-1
CAS:<p>Rbin-1 (Ribozinoindole-1) is a potent,specific inhibitor of eukaryotic ribosome biogenesis.</p>Fórmula:C13H12N4SPureza:99.83%Cor e Forma:SolidPeso molecular:256.33Enflurane
CAS:<p>Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.</p>Fórmula:C3H2ClF5OPureza:99.64%Cor e Forma:Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnPeso molecular:184.49Azimilide Dihydrochloride
CAS:Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the IKs and IKr with antiarrhythmic activity.Fórmula:C23H30Cl3N5O3Pureza:97.59% - ≥95%Cor e Forma:SolidPeso molecular:530.88Fipronil
CAS:<p>Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.</p>Fórmula:C12H4Cl2F6N4OSPureza:97.21%Cor e Forma:Solid PowderPeso molecular:437.15KB-R7943 mesylate
CAS:<p>KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.</p>Fórmula:C17H21N3O6S2Pureza:99.88% - ≥95%Cor e Forma:SolidPeso molecular:427.5Nicainoprol
CAS:<p>Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent.</p>Fórmula:C21H27N3O3Pureza:99.54%Cor e Forma:SolidPeso molecular:369.46Amlodipine mesylate
CAS:<p>Amlodipine mesylate, an oral dihydropyridine Ca2+ blocker, treats angina, hypertension, and may be used in cancer research.</p>Fórmula:C21H29ClN2O8SCor e Forma:SolidPeso molecular:504.98DS-1971a
CAS:<p>DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.</p>Fórmula:C20H21ClFN5O3SPureza:99.66%Cor e Forma:SolidPeso molecular:465.93Jujuboside A
CAS:<p>Jujuboside A: glycoside from Semen Ziziphi Spinosae, may treat Alzheimer's, has neuro-inhibitory effects.</p>Fórmula:C58H94O26Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:1207.35Rufinamide
CAS:<p>Rufinamide (E 2080), a triazole derivative, is used as voltage-gated sodium channel blocker for the treatment of seizure disorders.</p>Fórmula:C10H8F2N4OPureza:99.77% - >99.99%Cor e Forma:White PowderPeso molecular:238.19
