Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(92 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(66 produtos)
- Receptor CGRP(55 produtos)
- Canais de Cálcio(578 produtos)
- Canal de cloreto(53 produtos)
- Receptor GABA(367 produtos)
- Transportador de monoamina(30 produtos)
- Transportador de monocarboxilato(18 produtos)
- NKCC(2 produtos)
- NPC1L1(1 produtos)
- Cotransportador Na-K-Cl(9 produtos)
- OAT(31 produtos)
- OCT(7 produtos)
- P-gp(56 produtos)
- Canal de Potássio(319 produtos)
- Bomba de prótons(42 produtos)
- SGLT(32 produtos)
- Canal de Sódio(273 produtos)
- Canal TRP/TRPV(97 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2694 produtos para "Transportador de Membranas/Canal Iónico".
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Nefiracetam
CAS:Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.Fórmula:C14H18N2O2Pureza:97.37%Cor e Forma:SolidPeso molecular:246.3DCPIB
CAS:DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μMFórmula:C22H28Cl2O4Pureza:99.79% - 99.87%Cor e Forma:SolidPeso molecular:427.36Ref: TM-T10979
2mg39,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg87,00€25mg177,00€50mg301,00€100mg485,00€200mg690,00€NaV1.7 inhibitor-1
CAS:NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).Fórmula:C23H30FNO4SPureza:99.89%Cor e Forma:SolidPeso molecular:435.55Ref: TM-T12181
1mg99,00€5mg241,00€1mL*10mM (DMSO)265,00€10mg385,00€25mg663,00€50mg888,00€100mg1.305,00€3,4,5-Trimethoxycinnamic acid
CAS:3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at theFórmula:C12H14O5Pureza:98.91%Cor e Forma:SolidPeso molecular:238.24Tolazamide
CAS:Tolazamide (U-17835) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.Fórmula:C14H21N3O3SPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:311.40Ref: TM-T1333
2mg34,00€5mg50,00€1mL*10mM (DMSO)58,00€10mg66,00€25mg92,00€50mg118,00€100mg152,00€200mg219,00€Mephenesin
CAS:Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.Fórmula:C10H14O3Pureza:99.49% - 99.87%Cor e Forma:SolidPeso molecular:182.22GV-58
CAS:GV-58 agonizes N/P-Q-type Ca2+ channels (EC50: 7.21/8.81 μM) with 20x less inhibition on CDK kinases.Fórmula:C18H26N6OSPureza:97.36%Cor e Forma:Yellow SolidPeso molecular:374.5Ref: TM-T11517
1mg49,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg205,00€25mg409,00€50mg592,00€100mg827,00€500mg1.648,00€IK1 inhibitor PA-6
CAS:IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouseFórmula:C31H32N4O2Pureza:98.9%Cor e Forma:SolidPeso molecular:492.61Cav 2.2 blocker 1
CAS:Cav 2.2 blocker 1 is an N-type calcium channel (Cav 2.2; IC50: 1 nM) blocker for the treatment of pain.Fórmula:C25H29ClN2O2Pureza:99.44%Cor e Forma:SolidPeso molecular:424.96Ref: TM-T10690
1mg48,00€5mg105,00€1mL*10mM (DMSO)111,00€10mg173,00€25mg323,00€50mg494,00€100mg740,00€200mg973,00€Boc-LRR-AMC TFA
Boc-LRR-AMC TFA is a fluorogenic protease substrate for detecting trypsin-like activity in the 26S proteasome or 20S proteasome core.Fórmula:C35H53F3N10O9Pureza:97.70%Cor e Forma:SolidPeso molecular:814.85QX-314 chloride
CAS:QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.Fórmula:C16H27ClN2OPureza:99.73%Cor e Forma:SolidPeso molecular:298.85Clevidipine
CAS:Clevidipine (Clevidipine butyrate) is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for bloodFórmula:C21H23Cl2NO6Pureza:99.40%Cor e Forma:PowderPeso molecular:456.32MRZ 2-514
CAS:MRZ 2-514 (8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one) is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with KiFórmula:C11H6BrN3O3Pureza:98.45%Cor e Forma:SolidPeso molecular:308.09Ref: TM-T12110
1mg92,00€5mg192,00€1mL*10mM (DMSO)212,00€10mg313,00€25mg620,00€50mg1.044,00€100mg1.404,00€Indapamide
CAS:Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.Fórmula:C16H16ClN3O3SPureza:98.97% - 99.83%Cor e Forma:SolidPeso molecular:365.83Org-26576
CAS:Org-26576 is a positive allosteric modulator of the AMPA receptor.Fórmula:C11H12N2O2Pureza:99.67%Cor e Forma:White SolidPeso molecular:204.23Diltiazem hydrochloride
CAS:Diltiazem hydrochloride (RG 83606 HCl) is a benzothiazepine calcium channel blocking agent with vasodilating action.Fórmula:C22H27ClN2O4SPureza:98% - 99.65%Cor e Forma:SolidPeso molecular:450.98Vocacapsaicin hydrochloride
CAS:Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.Fórmula:C26H42ClN3O4Pureza:99.66% - 99.80%Cor e Forma:SolidPeso molecular:496.08Caldaret HCl
CAS:Caldaret HCl is an intracellular Ca2+ modulator that regulates calcium homeostasis at the sarcoplasmic reticulum and cell membrane, and can be used to study acute myocardial infarction and heart failure.Fórmula:C11H17ClN2O3SPureza:99.16%Cor e Forma:Yellow SolidPeso molecular:292.78CRAC intermediate 1
CAS:CRAC intermediate 1 (5-(S)-Fluorowillardiine) is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors.Fórmula:C10H7F2N3OPureza:99.77%Cor e Forma:White SolidPeso molecular:223.18Bemegride
CAS:Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.Fórmula:C8H13NO2Pureza:99.89%Cor e Forma:SolidPeso molecular:155.19Fluxametamide
CAS:Fluxametamide, an isoxazoline insecticide, targets insect chloride channels with IC50s of 1.95 nM (GABA) and 225 nM (glutamate).Fórmula:C20H16Cl2F3N3O3Pureza:99.49%Cor e Forma:SolidPeso molecular:474.26L-Cycloserine
CAS:L-Cycloserine irreversibly inhibits E. coli GABA aminotransferase, raising GABA levels, an inhibitory neurotransmitter.Fórmula:C3H6N2O2Pureza:99.92% - 99.99%Cor e Forma:White SolidPeso molecular:102.09Ropivacaine
CAS:Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.Fórmula:C17H26N2OPureza:97.75% - >99.99%Cor e Forma:SolidPeso molecular:274.40Amlodipine
CAS:Amlodipine (UK-48340) is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.Fórmula:C20H25ClN2O5Pureza:99.33% - 99.60%Cor e Forma:SolidPeso molecular:408.88(E/Z)-Sivopixant
CAS:(E/Z)-Sivopixant ((E/Z)-S-600918)is a potent P2X3 receptor antagonist, IC50 = 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research.Fórmula:C25H22ClN5O5Pureza:99.82%Cor e Forma:SolidPeso molecular:507.93Ref: TM-T9653
1mg92,00€5mg200,00€1mL*10mM (DMSO)225,00€10mg299,00€25mg484,00€50mg658,00€100mg892,00€500mg1.773,00€Orphenadrine Citrate
CAS:Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.Fórmula:C18H23NO·C6H8O7Pureza:99.58%Cor e Forma:White SolidPeso molecular:461.5Dofequidar fumarate
CAS:Dofequidar fumarate (MS-209)(MS-209 fumarate), a quinoline-based compound administered orally, is known for counteracting multidrug resistance (MDR) through theFórmula:C34H35N3O7Pureza:99.93%Cor e Forma:SolidPeso molecular:597.66Ref: TM-T11071
1mg37,00€2mg52,00€5mg80,00€1mL*10mM (DMSO)90,00€10mg118,00€25mg233,00€50mg447,00€100mg650,00€500mg1.369,00€Dooku1
CAS:Dooku1, Yoda1 analog, blocks Piezo1 channels, halting Ca2+ entry. IC50: 1.3μM in HEK 293, 1.5μM in HUVEC, stops Yoda1's aortic relaxation.Fórmula:C13H9Cl2N3OSPureza:98.87% - 99.74%Cor e Forma:SolidPeso molecular:326.2Ref: TM-T11076
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg133,00€25mg259,00€50mg482,00€100mg695,00€Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Fórmula:C12H10ClN2NaO5SPureza:99.52% - >99.99%Cor e Forma:SolidPeso molecular:352.73Otilonium bromide
CAS:Otilonium bromide (SP63) , an antimuscarinic, is utilized as a spasmolytic agent.Fórmula:C29H43BrN2O4Pureza:99.78% - 99.88%Cor e Forma:SolidPeso molecular:563.57Carboxyamidotriazole Orotate
CAS:Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signalingFórmula:C22H16Cl3N7O6Pureza:99.37%Cor e Forma:SolidPeso molecular:580.76TPC2-A1-P
CAS:TPC2-A1-P is a TPC2 agonist that can differentially activate two-pore channel 2 (TPC2) and mimic the activation of TPC2 with NAADP and PIP (2).Fórmula:C20H21BrF3NO3Pureza:98.49%Cor e Forma:SolidPeso molecular:460.29Ref: TM-T36806
1mg92,00€5mg225,00€1mL*10mM (DMSO)226,00€10mg374,00€25mg710,00€50mg1.153,00€100mg1.755,00€NS13001
CAS:NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).Fórmula:C17H16ClN7Pureza:99.55%Cor e Forma:White SolidPeso molecular:353.81Manidipine dihydrochloride
CAS:Manidipine dihydrochloride (Manidipine 2HCl) is a potent calcium channel blocker for Ca2+ current(IC50=2.6 nM).Fórmula:C35H40Cl2N4O6Pureza:99.76% - 99.86%Cor e Forma:SolidPeso molecular:683.62Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Fórmula:C11H15NO5Pureza:99.96%Cor e Forma:White SolidPeso molecular:241.24ML418
CAS:ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.Fórmula:C19H24ClN3O3Pureza:99.3%Cor e Forma:SolidPeso molecular:377.87Ref: TM-T16110
1mg37,00€5mg79,00€1mL*10mM (DMSO)84,00€10mg111,00€25mg178,00€50mg288,00€100mg414,00€200mg583,00€γ-Aminobutyric acid
CAS:γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.Fórmula:C4H9NO2Pureza:99.95%Cor e Forma:White SolidPeso molecular:103.12Baclofen
CAS:Baclofen (Lioresal), a chlorophenyl-butanoic acid derivative, treats spasms from spinal cord injury and MS by mimicking GABA at GABA-B receptors.Fórmula:C10H12ClNO2Pureza:98% - 99.94%Cor e Forma:White SolidPeso molecular:213.66FFN 511
CAS:Fluorescent false neurotransmitter (FFN)Fórmula:C17H20N2O2Pureza:98%Cor e Forma:SolidPeso molecular:284.35Prilocaine hydrochloride
CAS:Prilocaine HCl: local amino amide anesthetic, blocks voltage-gated sodium channels in neurons, inhibits Na+ permeability.Fórmula:C13H21ClN2OPureza:99.97%Cor e Forma:SolidPeso molecular:256.77Suloctidil
CAS:Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders.Fórmula:C20H35NOSPureza:99.75% - >99.99%Cor e Forma:White SolidPeso molecular:337.56VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuitFórmula:C20H22ClFN4O2SPureza:98.1%Cor e Forma:SolidPeso molecular:436.93PSB-12062
CAS:PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4).Fórmula:C19H15NO3SPureza:99.43% - 99.84%Cor e Forma:SolidPeso molecular:337.39Celivarone
CAS:Celivarone is a potassium channel blocker used in the study of arrhythmias, atrial flutter and atrial fibrillation.Fórmula:C34H47NO4Pureza:99.53%Cor e Forma:SolidPeso molecular:533.74IA-Alkyne
CAS:IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.Fórmula:C8H12INOPureza:99.76%Cor e Forma:White SolidPeso molecular:265.09Ref: TM-T15543
1mg56,00€1mL*10mM (DMSO)114,00€5mg119,00€10mg177,00€25mg250,00€50mg313,00€100mg432,00€Clorsulon
CAS:Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.Fórmula:C8H8Cl3N3O4S2Pureza:99.66% - 99.87%Cor e Forma:SolidPeso molecular:380.66T16Ainh-A01
CAS:T16Ainh-A01 is a potent TMEM16A chloride channel inhibitor with a 1 μM IC50, targeting CaCC.Fórmula:C19H20N4O3S2Pureza:97.18% - 98.15%Cor e Forma:SolidPeso molecular:416.52NS3623
CAS:NS3623 is an activator of human ether-a-go-go-related gene potassium channels.Fórmula:C15H10BrF3N6OPureza:97.06%Cor e Forma:SolidPeso molecular:427.184-Aminopyridine
CAS:4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.Fórmula:C5H6N2Pureza:91.61%Cor e Forma:SolidPeso molecular:94.11BAY-1797
CAS:BAY-1797: oral P2X4 blocker, IC50 211 nM, anti-pain/inflammation, barely affects other P2X channels.Fórmula:C20H17ClN2O4SPureza:98.01%Cor e Forma:SolidPeso molecular:416.88
