Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(98 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(66 produtos)
- Receptor CGRP(54 produtos)
- Canais de Cálcio(528 produtos)
- Canal de cloreto(52 produtos)
- Receptor GABA(360 produtos)
- Transportador de monoamina(28 produtos)
- Transportador de monocarboxilato(18 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(9 produtos)
- OAT(31 produtos)
- OCT(7 produtos)
- P-gp(54 produtos)
- Canal de Potássio(280 produtos)
- Bomba de prótons(42 produtos)
- SGLT(31 produtos)
- Canal de Sódio(206 produtos)
- Canal TRP/TRPV(94 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2460 produtos de "Transportador de Membranas/Canal Iónico"
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U-7524
CAS:U-7524 (AOAA), an inhibitor of GABA-T and other PLP-dependent enzymes, disrupts the Schiff base linkage, forming oxime complexes.Fórmula:C2H5NO3Cor e Forma:SolidPeso molecular:91.073-Methyl-GABA
CAS:3-Methyl-GABA activates GABA aminotransferase, fits GABAaR, stimulates GAD, and acts as an anticonvulsant.Fórmula:C20H30N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:522.59Ethyl dirazepate
CAS:Ethyl dirazepate has anxiolytic and hypnotic and possibly other characteristic benzodiazepine properties,is a drug which is a benzodiazepine derivative.Fórmula:C18H14Cl2N2O3Pureza:98%Cor e Forma:SolidPeso molecular:377.22UBP301
CAS:UBP301 is a kainate receptor antagonist.Fórmula:C15H14IN3O6Pureza:98%Cor e Forma:SolidPeso molecular:459.19Felbamate hydrate
CAS:Felbamate hydrate is an effective nonsedative anticonvulsant. It is a clinical effect that may be related to the inhibition of N-methyl-D-aspartate.Fórmula:C11H16N2O5Pureza:98%Cor e Forma:SolidPeso molecular:256.26Arbaclofen placarbil
CAS:Arbaclofen placarbil is a GABA(B) receptor agonist with better ADMET than R-baclofen, reducing postprandial reflux in GERD.Fórmula:C19H26ClNO6Cor e Forma:SolidPeso molecular:399.87Carburazepam
CAS:Carburazepam is a derivate of benzodiazepines. Benzodiazepines are a class of psychoactive drugs.Fórmula:C17H16ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:329.78Cibenzoline
CAS:Cibenzoline: antiarrhythmic, blocks KATP channels, minimizes LVPG, useful in hypertrophic cardiomyopathy studies.Fórmula:C18H18N2Cor e Forma:SolidPeso molecular:262.35URAT1&XO inhibitor 2
CAS:Compound BDEO (URAT1&XO inhibitor 2) serves as a dual-action inhibitor targeting both xanthine oxidase (XO) and URAT1, demonstrating an IC50 value of 3.3 μM forFórmula:C14H12BrNO3Pureza:98%Cor e Forma:SolidPeso molecular:322.15TCS 1105
CAS:TCS 1105 is a GABAA BZR ligand, blocking Sema3A and altering mouse anxiety, aggression, and social dominance.Fórmula:C17H13FN2O2Pureza:99.75%Cor e Forma:SolidPeso molecular:296.3(R)-CPP
CAS:(R)-CPP is a NMDA antagonist.Fórmula:C8H17N2O5PPureza:98%Cor e Forma:SolidPeso molecular:252.2PD-151307
CAS:PD-151307 is used as an N-type calcium channel blocker.Fórmula:C33H47N3O5Pureza:98%Cor e Forma:SolidPeso molecular:565.74SN05
CAS:<p>SN05 inhibits AAT with Ki: ASCT1 (2.77μM), rASCT2 (0.73μM), hASCT2 (0.87μM), EAAT1-5 (3.7-7.25μM); used in cancer research.</p>Fórmula:C18H17NO4Cor e Forma:SolidPeso molecular:311.33RU 33965
CAS:RU 33965, a 3-cyclopropyl carbonyl imidazobenzodiazepine, act as a low-efficacy benzodiazepine receptor inverse agonist.Fórmula:C16H15N3O2Pureza:98%Cor e Forma:SolidPeso molecular:281.31Dihydrocapsiate
CAS:Dihydrocapsiate is a compound of capsinoid family that can be used in metabolism diseas research. Dihydrocapsiate is an orally active agonist of TRPV1 [1].Fórmula:C18H28O4Cor e Forma:SolidPeso molecular:308.41BTG-1640
CAS:BTG-1640 is used potentially for the treatment of anxiety and panic disorder.Fórmula:C15H19NO2Cor e Forma:SolidPeso molecular:245.32MCC-134
CAS:MCC-134 is an inverse agonist for the pancreatic-type ATP-sensitive K(+) channel. It also used as a vascular relaxing agent.Fórmula:C16H17N3OSCor e Forma:SolidPeso molecular:299.39(Rac)-MEM 1003
CAS:MEM-1003, a calcium channel blocker, is used potentially for the treatment of bipolar disorders.Fórmula:C22H25ClN2O5Cor e Forma:SolidPeso molecular:432.9(S)-AMPA
CAS:(S)-AMPA is an active isomer of AMPA and a selective agonist of AMPA.Fórmula:C7H10N2O4Cor e Forma:SolidPeso molecular:186.17DDO-02005 free base
CAS:DDO-02005 is a potent Kv1.5 inhibitor with IC50 of 0.72μM, showing strong anti-arrhythmic and anti-AF effects in rat models.Fórmula:C21H25N3O2Cor e Forma:SolidPeso molecular:351.44NS-8
CAS:NS-8, a pyrrole, activates Ca2+-sensitive K+ channels, reducing urinary frequency by inhibiting pelvic nerve activity.Fórmula:C12H10FN3Cor e Forma:SolidPeso molecular:215.23Sadopine
CAS:Sadopine is a high-affinity radioligand for DHP receptor in L-type Ca2+ channels, suitable for tissue and membrane labeling.Fórmula:C30H40F3N3O7SCor e Forma:SolidPeso molecular:643.71P2X7 receptor antagonist-2
CAS:P2X7 receptor antagonist-2: potent, pIC50 6.5-7.5, reduces neuroinflammation.Fórmula:C19H18Cl2N2O2Cor e Forma:SolidPeso molecular:377.26Bts 39542
CAS:Bts 39542 is a diuretic that plays a major role in the Henle circulation and increases renal blood flow without affecting glomerular filtration rate.Fórmula:C16H11ClN4O3SCor e Forma:SolidPeso molecular:374.8UBP646
CAS:UBP646 is a GluN1/GluN2 receptors potentiator.Fórmula:C21H22O2Pureza:98%Cor e Forma:SolidPeso molecular:306.4NMDA receptor modulator 2
CAS:NMDA receptor modulator 2 (Compound 1) is a potent modulator of the NMDA receptor that can be used for neurological disorder research [1].Fórmula:C13H11F3N2O2Cor e Forma:SolidPeso molecular:284.23NAP-1
CAS:<p>NAP-1 is an anesthetic that enhances CA1 brain inhibition in rats and causes tadpole sedation (EC50 = 0.53 μM).</p>Fórmula:C20H18ClNO2Cor e Forma:SolidPeso molecular:339.82TRPC5-IN-2
CAS:TRPC5-IN-2 is a potent inhibitor of TRPC5.Fórmula:C17H14ClF3N6OCor e Forma:SolidPeso molecular:410.78CGP 39551
CAS:CGP 39551 is a NMDA antagonist.Fórmula:C8H16NO5PPureza:98%Cor e Forma:White SolidPeso molecular:237.19bis(7)-Tacrine
CAS:Bis(7)-tacrine dihydrochloride: dimeric AChE inhibitor; may treat Alzheimer's; blocks NMDA, antagonizes GABA A.Fórmula:C33H42Cl2N4Cor e Forma:SolidPeso molecular:565.63AS1928370
CAS:AS1928370 is an antagonist of transient receptor potential vanilloid 1 (TRPV1).Fórmula:C29H31N3O2Cor e Forma:SolidPeso molecular:453.58NAB-14
CAS:NAB-14: non-competitive GluN2C/D antagonist, IC50 580 nM for GluN1/2D, >800x selectivity over GluN2A/B, blood-brain-barrier penetrant.Fórmula:C20H21N3O3Cor e Forma:SolidPeso molecular:351.4Ac32Az19
CAS:Ac32Az19 is a potent, non-toxic, and highly selective inhibitor of Breast Cancer Resistance Protein (BCRP), demonstrating an EC50 of 13 nM in BCRP-overexpressedFórmula:C37H33N3O6Cor e Forma:SolidPeso molecular:615.67GABAA receptor agent 7
CAS:Compound 5c, a GABAA receptor modulator with anticonvulsant properties and low neurotoxicity, is promising for epilepsy research.Fórmula:C18H13ClN4OCor e Forma:SolidPeso molecular:336.77ZK93423
CAS:ZK93423: potent benzodiazepine agonist, IC50=1nM, non-selective, Ki=4.1-6nM for α1-α5 GABAA subunits.Fórmula:C23H22N2O4Cor e Forma:SolidPeso molecular:390.43AMG-1
CAS:AMG-1 inhibits CRAC channels, blocks effector T cells, not regulatory ones, and reduces EAE progression.Fórmula:C18H9ClF5N3OCor e Forma:SolidPeso molecular:413.73Efflux inhibitor-1
CAS:Efflux inhibitor-1 is a pyrazolopyrimidine efflux inhibitor.Fórmula:C28H25N5O3Cor e Forma:SolidPeso molecular:479.53(Rac)-NMDAR antagonist 1
CAS:(Rac)-NMDAR antagonist 1 is a racemate of NMDAR antagonist 1. NMDAR antagonist 1 is a potent, orally active, NR2B-selective NMDAR antagonist.Fórmula:C20H20BrN3O2Cor e Forma:SolidPeso molecular:414.3P-gp inhibitor 3
P-gp inhibitor 3 boosts Paclitaxel's effect by strongly reversing MDR via P-gp efflux blockade.Fórmula:C48H67N3O6Cor e Forma:SolidPeso molecular:782.06Clobutinol
CAS:Clobutinol has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research [1] [2] [3].Fórmula:C14H22ClNOCor e Forma:SolidPeso molecular:255.78(R)-Posenacaftor sodium
CAS:(R)-Posenacaftor sodium is a modulator for correcting cystic fibrosis protein folding.Fórmula:C27H27NNaO5Cor e Forma:SolidPeso molecular:468.505P-CAB agent 2 hydrochloride
CAS:P-CAB agent 2 hydrochloride is a strong oral gastric acid secretion inhibitor with IC50 <100 nM on H+/K+ ATPase and 18.69 µM on hERG channel, non-toxic.Fórmula:C22H26ClFN2O4SCor e Forma:SolidPeso molecular:468.97SK3 Channel-IN-1
CAS:<p>SK3 Channel-IN-1: Potent, selective SK3 modulator; inhibits MDA-MB-435 migration, low cytotoxicity.</p>Fórmula:C25H49NOCor e Forma:SolidPeso molecular:379.66Xininurad
CAS:Xininurad (XNW3009) is a urate transporter (URAT) inhibitor.Fórmula:C15H10Br2FN3O2Cor e Forma:SolidPeso molecular:443.07MRS-1477
CAS:MRS-1477 is used as a TRPV1 positive allosteric modulator (PAM).Fórmula:C21H27NO4SPureza:98%Cor e Forma:SolidPeso molecular:389.51Cgp 31358
CAS:CGP 31358 is a new chemical that targets the NMDA receptor, potentially aiding in molecular pharmacology research.Fórmula:C19H19ClN4O2Cor e Forma:SolidPeso molecular:370.83(1R,2R)-ML-SI3
CAS:(1R,2R)-ML-SI3 ((-)-trans-ML-SI3) is a selective TRPML1, TRPML2, and TRPML3 inhibitor for the study of neurodegenerative and cardiovascular diseases.Fórmula:C23H31N3O3SCor e Forma:SolidPeso molecular:429.58GLPG-3221
CAS:GLPG-3221, a potent oral CFTR corrector for cystic fibrosis treatment, has an EC50 of 105 nM.Fórmula:C30H37F3N2O6Pureza:98%Cor e Forma:SolidPeso molecular:578.62IDO1-IN-19
CAS:IDO1-IN-19 (Compound 17) is a potent inhibitor of IDO1 and has potential for cancer disease research.Fórmula:C25H22F4N2O3Cor e Forma:SolidPeso molecular:474.45P2X7 receptor antagonist-3
CAS:P2X7 receptor antagonist-3 is a powerful inhibitor of the P2X7 receptor, exhibiting IC50 values of 4.2 nM in humans and 6.8 nM in rats, indicating its highFórmula:C17H12ClF3N6OCor e Forma:SolidPeso molecular:408.77
