Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(98 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(66 produtos)
- Receptor CGRP(53 produtos)
- Canais de Cálcio(525 produtos)
- Canal de cloreto(51 produtos)
- Receptor GABA(355 produtos)
- Transportador de monoamina(26 produtos)
- Transportador de monocarboxilato(18 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(9 produtos)
- OAT(28 produtos)
- OCT(7 produtos)
- P-gp(52 produtos)
- Canal de Potássio(280 produtos)
- Bomba de prótons(40 produtos)
- SGLT(31 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(94 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2430 produtos de "Transportador de Membranas/Canal Iónico"
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CP 339818 hydrochloride
CAS:<p>KV1.3 channel antagonist</p>Fórmula:C21H25ClN2Pureza:98%Cor e Forma:SolidPeso molecular:340.89Vincanol
CAS:Vincanol is a potent voltage-gated Na+ channels blocker.Fórmula:C19H24N2OPureza:98%Cor e Forma:SolidPeso molecular:296.41NS004
CAS:NS004 is a large-conductance K+ channel opener, it inhibits mitochondrial function in glioma cells.Fórmula:C14H8ClF3N2O2Pureza:98%Cor e Forma:SolidPeso molecular:328.67KCa2 channel modulator 1
CAS:<p>Compound 2o, a selective K/Ca2 channel enhancer, boosts rat K Ca 2.2 (EC50: 0.99 μM) and human K Ca 2.3 (EC50: 0.19 μM).</p>Fórmula:C16H15ClFN5Cor e Forma:SolidPeso molecular:331.78Leconotide
CAS:Leconotide is a calcium channel blocker and antihyperalgesia agent; isolated from the venom of the cone snail, Conus catus.Fórmula:C107H179N35O36S7Cor e Forma:SolidPeso molecular:2756.23TTA-P2
CAS:TTA-P2: potent CNS-penetrating T-type Ca2+ channel blocker; eliminates Cav3.1 window currents.Fórmula:C21H29Cl2FN2O2Cor e Forma:SolidPeso molecular:431.37NAV26
CAS:NAV26 is a selective blocker of the Nav1.7 channel.Fórmula:C22H21F3N2O4Pureza:98%Cor e Forma:SolidPeso molecular:434.41GABAA receptor modulator-2
CAS:<p>Compound 20: Selective, oral α5-GABAAR inhibitor, Ki: 4.1 nM. High stability, CNS safe.</p>Fórmula:C22H22FN3O5SCor e Forma:SolidPeso molecular:459.49ANO1-IN-2
CAS:ANO1-IN-2: potent ANO1 blocker (IC50: 1.75 μM), less effective on ANO2 (IC50: 7.43 μM), inhibits glioblastoma cell growth.Fórmula:C16H14ClN3O2S2Cor e Forma:SolidPeso molecular:379.88BMS-284640
CAS:<p>BMS-284640 is a NHE inhibitor that protects against MI in animal studies.</p>Fórmula:C15H19N3O2Cor e Forma:SolidPeso molecular:273.33Lanicemine
CAS:Lanicemine is a low-trapping NMDA channel blocker. It also has a binding (Ki: 0.56-2.1 μM).Fórmula:C13H14N2Pureza:98%Cor e Forma:SolidPeso molecular:198.26P2X2/3 modulator-1
CAS:Compound 46, a P2X2/3 modulator, could aid in research of pain, CNS disorders, and inflammation.Fórmula:C26H21N5OCor e Forma:SolidPeso molecular:419.48UTA1inh-C1
CAS:UTA1inh-C1 is a novel inhibitor of kidney urea transporter UT-A1.Fórmula:C22H24N6O4S2Cor e Forma:SolidPeso molecular:500.59TRPC6-IN-3
CAS:<p>TRPC6-IN-3 is an oral TRPC6 ion channel inhibitor, regulating calcium levels and membrane potential.</p>Fórmula:C22H22FN5O3Cor e Forma:SolidPeso molecular:423.44KR-30450
CAS:KR-30450, a potassium channel agonist, is used potentially for the treatment of hypertension.Fórmula:C17H18N2O6Cor e Forma:SolidPeso molecular:346.33Taquidil
CAS:Tocainide hydrochloride: oral antiarrhythmic, sodium channel blocker, akin to lidocaine.Fórmula:C11H17ClN2OCor e Forma:SolidPeso molecular:228.718P-gp inhibitor 4
CAS:P-gp inhibitor 4 is a selective P-glycoprotein modulator with an EC 50 of 94 nM.Fórmula:C38H38N2O8S2Cor e Forma:SolidPeso molecular:714.85NMDA-IN-2
CAS:NMDA-IN-2 (compound 6b) is a Procaine derivative that is an inhibitor of NMDA receptor 2B subtype [1].Fórmula:C15H22N2O3Cor e Forma:SolidPeso molecular:278.35PD-307243
CAS:PD-307243 is an activator of hERG channel.Fórmula:C20H15Cl2N3O2Cor e Forma:SolidPeso molecular:400.26RQ-00311651
CAS:RQ-00311651 is a novel T-type Ca2+ channel blocker. RQ-00311651 also inhibited high K-induced Ca signaling in those cells.Fórmula:C19H18F3N5O2Cor e Forma:SolidPeso molecular:405.37DDO-02005
CAS:DDO-02005, a Kv1.5 inhibitor (IC50: 0.72 μM), counters fibrillation and arrhythmias in rats.Fórmula:C21H27Cl2N3O2Cor e Forma:SolidPeso molecular:424.37(±)-C3001a
CAS:(RS)-C3001a is the racemic mixture of C3001a (CAS: 2415154-29-7). C3001a is a selective activator of the TREK channel.Fórmula:C21H20N2O3SPureza:99.13%Cor e Forma:SolidPeso molecular:380.46TRPC3/6-IN-1
CAS:<p>TRPC3/6-IN-1 selectively inhibits hTRPC3/6 with IC50 of 1260/500 nM, useful in heart failure research.</p>Fórmula:C20H19N3O2SCor e Forma:SolidPeso molecular:365.45Ivacaftor-D9
CAS:<p>CTP-656, a cystic fibrosis transmembrane conductance regulator (CFTR) channel activator, is used potentially for the treatment of cystic fibrosis.</p>Fórmula:C24H19D9N2O3Cor e Forma:SolidPeso molecular:401.55RG100204
CAS:<p>RG100204 is an orally active AQP9 inhibitor with anti-inflammatory properties. It alleviates cardiac dysfunction (systolic and diastolic) induced by sepsis, improves renal dysfunction, and reduces the elevation of the cellular damage marker LDH.</p>Fórmula:C20H26N6O2S2Cor e Forma:SolidPeso molecular:446.59P-gp inhibitor 17
CAS:<p>P-gp Inhibitor 17 (compound 2g), a potent inhibitor, directly interacts with the transmembrane domain of P-gp. This compound is useful for studying P-gp-mediated multidrug resistance in tumor cells [1].</p>Fórmula:C36H49N3O3Cor e Forma:SolidPeso molecular:571.79CW0134
CAS:<p>CW0134 (Compound 12) serves as a modulator for exportin1 (XPO1), disrupting chromatin binding and inhibiting NFAT transcription factors and T cell activation [1].</p>Fórmula:C11H7ClF3N3O2Cor e Forma:SolidPeso molecular:305.64DPI 201-106
CAS:<p>DPI 201-106: cardioselective h1 Na channel inhibitor, enhances heart contraction, blocks potassium and calcium currents.</p>Fórmula:C29H30N4O2Pureza:99.94%Cor e Forma:SolidPeso molecular:466.57(+)-Nipecotic acid
CAS:(+)-Nipecotic acid ((+)-β-Homoproline) is a specific inhibitor of GABA transport and uptake, capable of activating GABAA receptors.Fórmula:C6H11NO2Pureza:99.38%Cor e Forma:SolidPeso molecular:129.16Anxiolytic/nonsedative agent-1
CAS:TCS 1205: Selective GABAA agonist, BzR affinity in bovine brain (Kis: 14-239 nM), α2 efficacy in vitro, anxioselective in vivo.Fórmula:C18H15N3O4Pureza:98.61%Cor e Forma:SolidPeso molecular:337.33(S)-SNAP5114
CAS:<p>(S)-SNAP5114 is a selective inhibitor of GABA transport with IC50s of 5 μM for hGAT-3 and 21 μM for rGAT-2. (S)-SNAP5114 has anticonvulsant properties.</p>Fórmula:C30H35NO6Pureza:97%Cor e Forma:SolidPeso molecular:505.6Psora 4
CAS:<p>Psora 4 (5-(4-Phenylbutoxy)psoralen) is a Kv1.3 blocker and a caloric restriction mimetic.</p>Fórmula:C21H18O4Cor e Forma:SolidPeso molecular:334.373α,21-Dihydroxy-5α-pregnan-20-one
CAS:<p>3α,21-Dihydroxy-5α-pregnan-20-one (5alpha-THDOC) is a GABAA modulator that can be used in the study of Alzheimer's-like neurological diseases.</p>Fórmula:C21H34O3Pureza:98.00%Cor e Forma:SolidPeso molecular:334.49AVE-0118
CAS:AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.Fórmula:C30H29N3O3Pureza:97.04% - 98.93%Cor e Forma:SolidPeso molecular:479.57L589-420
CAS:<p>L589-420 is a sodium pump inhibitor in human erythrocytes.</p>Fórmula:C14H14Cl2O4Pureza:98%Cor e Forma:SolidPeso molecular:317.16YM928
CAS:YM928 is an orally active antagonist of the AMPA receptor.Fórmula:C14H10ClN3OSPureza:98%Cor e Forma:SolidPeso molecular:303.77CCMQ
CAS:inhibits [3H]-homoquinolinic acid binding to non-NMDA sensitive sitesFórmula:C12H9NO4Pureza:98%Cor e Forma:SolidPeso molecular:231.2Bms 188107
CAS:Bms 188107 is a calcium antagonist, it has cardioprotective effects.Fórmula:C25H26N2O4Pureza:98%Cor e Forma:SolidPeso molecular:418.48Caramiphen
CAS:Caramiphen is an antimuscarinic and anticholinergic agent that acts as an antagonist of the NMDA receptor.Fórmula:C18H27NO2Pureza:98%Cor e Forma:SolidPeso molecular:289.41Viquidil
CAS:Viquidil is an agent with the activity of a vasodilator.Fórmula:C20H24N2O2Pureza:98%Cor e Forma:SolidPeso molecular:324.42(R)-Licarbazepine Acetate
CAS:(R)-Licarbazepine Acetate is a hopeful antiepileptic drug structurally related to Carbamazepine and Oxcarbazepine.Fórmula:C17H16N2O3Cor e Forma:SolidPeso molecular:296.32COR628
CAS:COR628 is the GABA(B) receptor positive allosteric modulator.Fórmula:C16H23NO3SCor e Forma:SolidPeso molecular:309.42AZD 2066
CAS:AZD 2066 is a selective, orally active, and brain-penetrant mGluR5 antagonist with analgesic activity.Fórmula:C19H16ClN5O2Pureza:98%Cor e Forma:SolidPeso molecular:381.82BBR 2160
CAS:<p>BBR 2160: a calcium-antagonist dihydropyridine derivative, reduces heart tissue contractility and shortens action potentials.</p>Fórmula:C21H25N3O7SCor e Forma:SolidPeso molecular:463.5LY-395153
CAS:LY-395153 is a novel potentiator of AMPA receptor.Fórmula:C19H24N2O3SCor e Forma:SolidPeso molecular:360.47Tolperisone free base
CAS:Tolperisone free base, a centrally acting muscle relaxant, has been used for the symptomatic treatment of spasticity and muscle spasm.Fórmula:C16H23NOPureza:98%Cor e Forma:SolidPeso molecular:245.36Lercanidipine, (S)-
CAS:(S)-Lercanidipine: a dihydropyridine calcium blocker with prolonged antihypertensive and kidney-protective properties.Fórmula:C36H41N3O6Pureza:98%Cor e Forma:SolidPeso molecular:611.73Ensaculin HCl
CAS:Ensaculin: NMDA antagonist, 5HT1A agonist, may treat Alzheimer's, enhances memory, neuroprotective, binds multiple receptors.Fórmula:C26H33ClN2O5Pureza:98%Cor e Forma:SolidPeso molecular:489Naftazone
CAS:Naftazone: vasoprotectant for hemostasis; boosts vein cell growth in vitro without affecting clotting.Fórmula:C11H9N3O2Pureza:98%Cor e Forma:SolidPeso molecular:215.21Tiropramide
CAS:Tiropramide is an antispasmodic drug. It also useful to inhibit the contractile response of the urinary bladder and in managing abdominal pain in IBS.Fórmula:C28H41N3O3Pureza:98%Cor e Forma:SolidPeso molecular:467.64
