Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(93 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(64 produtos)
- Receptor CGRP(52 produtos)
- Canais de Cálcio(496 produtos)
- Canal de cloreto(49 produtos)
- Receptor GABA(337 produtos)
- Transportador de monoamina(23 produtos)
- Transportador de monocarboxilato(17 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(8 produtos)
- OAT(27 produtos)
- OCT(7 produtos)
- P-gp(53 produtos)
- Canal de Potássio(277 produtos)
- Bomba de prótons(39 produtos)
- SGLT(30 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(93 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2293 produtos de "Transportador de Membranas/Canal Iónico"
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DMP-543
CAS:<p>DMP-543 (XR-543) is a potassium channel (KV7 channel) blocker that enhances the release of neurotransmitters.</p>Fórmula:C26H18F2N2OPureza:99.89%Cor e Forma:SolidPeso molecular:412.43Nisoxetine hydrochloride
CAS:Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitorFórmula:C17H21NO2·HClPureza:99.21%Cor e Forma:White SolidPeso molecular:307.828-Bromo-cGMP sodium
CAS:<p>8-Bromo-cGMP sodium: PKG activator, eases pain, dilates vessels, reduces Ca2+ currents & insulin release.</p>Fórmula:C10H10BrN5NaO7PPureza:99.45%Cor e Forma:SolidPeso molecular:446.09YM758
CAS:<p>YM758 is an inhibitor of If current channel.</p>Fórmula:C26H32FN3O4Pureza:99.65%Cor e Forma:SolidPeso molecular:469.55Ralitoline
CAS:<p>Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity.</p>Fórmula:C13H13ClN2O2SPureza:98.45%Cor e Forma:SolidPeso molecular:296.77ABT 102
CAS:<p>ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.</p>Fórmula:C21H24N4OPureza:98.38% - 99.86%Cor e Forma:SolidPeso molecular:348.44JNJ-26489112
CAS:<p>JNJ-26489112 is a CNS-active agent and an inhibitor of voltage-gated Na+ channels and N-type Ca2+ channels.</p>Fórmula:C9H11ClN2O4SPureza:99.31%Cor e Forma:SolidPeso molecular:278.71NHE3-IN-1
CAS:<p>NHE3-IN-1 是钠/质子交换剂 3 (NHE-3) 的抑制剂。</p>Fórmula:C12H10ClN3SPureza:99.93%Cor e Forma:SolidPeso molecular:263.75Silperisone HCl
CAS:<p>Silperisone HCl is a muscle relaxant and vasodilator, treating myoclonus, hypertonia, dystonia, and myospasm by blocking Na+ and Ca2+ channels.</p>Fórmula:C15H25ClFNSiPureza:99.62%Cor e Forma:SolidPeso molecular:301.9GW 542573X
CAS:<p>GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve</p>Fórmula:C19H28N2O5Pureza:99.91%Cor e Forma:SolidPeso molecular:364.44Divaplon
CAS:<p>Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.</p>Fórmula:C17H17N3O2Pureza:97.44% - 98.25%Cor e Forma:SolidPeso molecular:295.34Stepronin
CAS:<p>Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.</p>Fórmula:C10H11NO4S2Pureza:99.59%Cor e Forma:White Or Off White CrystallinePeso molecular:273.33Quinacainol
CAS:<p>Quinacainol (RP 54272) is a new antiarrhythmic compound with class I antiarrhythmic effects in rats.</p>Fórmula:C21H30N2OPureza:99.64%Cor e Forma:SolidPeso molecular:326.48L-838417
CAS:<p>L-838417 is a GABAA receptor subtype-selective benzodiazepine site-selective ligand and GABAA receptor-positive modulator used in the study of anxiety disorders</p>Fórmula:C19H19F2N7OPureza:98.12% - 99.70%Cor e Forma:SolidPeso molecular:399.4Indecainide
CAS:<p>Indecainide (Ricainid) is an antiarrhythmic compound that is carcinogenic and may be used in studies secondary to coronary artery disease.</p>Fórmula:C20H24N2OPureza:98.01% - 98.96%Cor e Forma:SolidPeso molecular:308.42DMT1 blocker 1
CAS:<p>DMT1 blocker 1 inhibits DMT1; IC50=0.64μM; may prevent intestinal iron absorption.</p>Fórmula:C16H14N4O2Pureza:99.73%Cor e Forma:SolidPeso molecular:294.31Trombodipine
CAS:<p>Trombodipine (PCA-4230) is a platelet aggregation inhibitor with antithrombotic activity and protection against Listeria monocytogenes.</p>Fórmula:C21H24N2O7SPureza:98.73% - 99.14%Cor e Forma:SolidPeso molecular:448.49DSP-0565
CAS:<p>DSP-0565 is a broad-spectrum anti-epileptic with a high safety margin and effectiveness in several convulsant models.</p>Fórmula:C14H12FNOPureza:99.51% - 99.56%Cor e Forma:SolidPeso molecular:229.25Tiludronate disodium
CAS:Tiludronate disodium: osteoclast inhibitor for metabolic bone disorder research.Fórmula:C7H7ClNa2O6P2SPureza:>99.99% - >99.99%Cor e Forma:Fine White To Off-White Crystalline PowderPeso molecular:362.57Progabide
CAS:<p>Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.</p>Fórmula:C17H16ClFN2O2Pureza:99.68%Cor e Forma:SolidPeso molecular:334.77Panadiplon
CAS:<p>Panadiplon (FG 10571) is a selective gamma-aminobutyric acid receptor agonist and partial agonist of 5GABAA, a benzodiazepine receptor, used in the treatment of</p>Fórmula:C18H17N5O2Pureza:98.30% - 98.94%Cor e Forma:SolidPeso molecular:335.36Gallopamil
CAS:Gallopamil blocks acid secretion (IC50: 10.9 μM), acts as antiarrhythmic, vasodilator, and is a methoxy Verapamil derivative.Fórmula:C28H40N2O5Pureza:99.85%Cor e Forma:SolidPeso molecular:484.63CP-060
CAS:<p>CP-060 is a potent Ca2+ antagonist and inhibits Ca2+ overload with antioxidant and cardioprotective activities.</p>Fórmula:C30H42N2O5SPureza:99.54%Cor e Forma:SolidPeso molecular:542.73IKs124
CAS:<p>IKs124 is a KCNE2/KCNQ1 potassium channel blocker, for hKCNE1 and hKCNE3, and can be used to study peptic ulcers.</p>Fórmula:C18H26N2O3SPureza:99.53%Cor e Forma:SolidPeso molecular:350.48Hepcidin antagonist-1
CAS:Heparin Antagonist-1 is an iron-regulating antagonist that can be used to study metabolic disorders such as iron deficiency diseases.Fórmula:C16H13Cl2N5Pureza:99.53% - 99.76%Cor e Forma:SolidPeso molecular:346.21Sipatrigine
CAS:Sipatrigine (619C89) is an inhibitor of glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channels.Fórmula:C15H16Cl3N5Pureza:98.64% - 99.77%Cor e Forma:SolidPeso molecular:372.68KR-32568
CAS:<p>KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM).</p>Fórmula:C13H12FN3O2Pureza:99.91%Cor e Forma:SolidPeso molecular:261.25MK-0448
CAS:<p>MK-0448 is a novel and selective blocker of the Kv1.5 (KCNA5) channel, a key channel involved in cardiac repolarization current I Kur.</p>Fórmula:C24H21FN4O2SPureza:99.25% - 99.79%Cor e Forma:SolidPeso molecular:448.51Rilmakalim
CAS:<p>Rilmakalim is a potassium channel opener. Rilmakalim shows antivasoconstrictor effect.</p>Fórmula:C21H23NO5SPureza:99.8% - 99.9%Cor e Forma:SolidPeso molecular:401.48Cirsimaritin
CAS:<p>Cirsimaritin has anti-bacterial, anti-inflammatory, anti-tumor, antioxidant effects, and protects kidneys; it weakly targets GABAA receptors.</p>Fórmula:C17H14O6Pureza:99.9%Cor e Forma:SolidPeso molecular:314.29Sulcardine sulfate
CAS:<p>Sulcardine sulfate (B-87823) is a multi-ion channel blocker with antiarrhythmic activity that inhibits Na+, K+, and Ca2+ channels.</p>Fórmula:C24H35N3O8S2Pureza:98.74%Cor e Forma:SolidPeso molecular:557.68Pyr3
CAS:<p>Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.</p>Fórmula:C16H11Cl3F3N3O3Pureza:98.04%Cor e Forma:SolidPeso molecular:456.63PG01
CAS:<p>PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.</p>Fórmula:C28H29N3O2Pureza:99.87%Cor e Forma:SolidPeso molecular:439.55RWJ-51204
CAS:<p>RWJ-51204: potent adenosine A2A blocker, GABA(A) partial agonist (IC50: 0.2-2 nM), neuroprotective, may treat Parkinson's.</p>Fórmula:C21H19F2N3O3Pureza:99.57% - 99.95%Cor e Forma:SolidPeso molecular:399.39SET 2
CAS:<p>SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.</p>Fórmula:C17H21F3N4O2SPureza:99.77%Cor e Forma:SolidPeso molecular:402.43Saviprazole
CAS:<p>Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.</p>Fórmula:C15H10F7N3O2S2Pureza:97.07% - 97.17%Cor e Forma:SolidPeso molecular:461.38SKA-111
CAS:SKA-111 activates KCa3.1 potassium channels, modulates membrane potential in endothelial cells, and dilates rat coronary arteries.Fórmula:C12H10N2SPureza:99.9%Cor e Forma:SolidPeso molecular:214.29SCH28080
CAS:<p>SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent</p>Fórmula:C17H15N3OPureza:99.24%Cor e Forma:SolidPeso molecular:277.32(+)-KCC2 blocker 1
CAS:<p>(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).</p>Fórmula:C22H25NO5SPureza:99.88%Cor e Forma:SolidPeso molecular:415.5TAK-653
CAS:<p>TAK-653 is a selective AMPA receptor PAM with minimal agonist activity, showing antidepressant-like effects and safety in rats.</p>Fórmula:C19H23N3O3SPureza:99.89%Cor e Forma:SolidPeso molecular:373.47AZD-1305
CAS:<p>AZD-1305: novel anti-arrhythmic blocking IKr, Ca, Na currents; useful in arrhythmia research.</p>Fórmula:C22H31FN4O4Pureza:99.31% - 99.86%Cor e Forma:SolidPeso molecular:434.5Alpidem
CAS:<p>Alpidem (Ananxyl), a non-sedative imidazopyridine anxiolytic, treats anxiety with high benzodiazepine receptor affinity.</p>Fórmula:C21H23Cl2N3OPureza:99.56% - 99.97%Cor e Forma:White To Off-White SolidPeso molecular:404.33Elpetrigine
CAS:<p>Elpetrigine (GW273293) is a potential sodium channel blocker with antiepileptic activity that can be used to study epilepsy.</p>Fórmula:C10H7Cl3N4Pureza:99.04% - 99.43%Cor e Forma:SolidPeso molecular:289.55ZTZ240
CAS:<p>ZTZ240 is a KCNQ2 channel activator used in the study of epilepsy.</p>Fórmula:C12H8ClFN2OPureza:99.89%Cor e Forma:SolidPeso molecular:250.66CNS-5161 hydrochloride
CAS:<p>CNS-5161 hydrochloride (CNS 5161A) is a new antagonist of NMDA ion-channel.</p>Fórmula:C16H19Cl2N3S2Pureza:99.53%Cor e Forma:SolidPeso molecular:388.38Temiverine hydrochloride
CAS:Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine.Fórmula:C24H36ClNO3Pureza:99.26% - 99.43%Cor e Forma:SolidPeso molecular:422L-Cysteine S-sulfate
CAS:<p>L-Cysteine S-sulfate (S-Sulfo-L-cysteine) is an effective N-methyl-d-aspartate (NMDA) glutamatergic receptors agonist.</p>Fórmula:C3H7NO5S2Pureza:99.90% - 99.92%Cor e Forma:SolidPeso molecular:201.22N106
CAS:<p>N106 is an activator of the SUMO-activating enzyme, E1 ligase, and triggers intrinsic sumoylation of SERCA2a. N106 can be used in studies about heart failure.</p>Fórmula:C17H14N4O3SPureza:99.69%Cor e Forma:SolidPeso molecular:354.38DFP00173
CAS:<p>DFP00173: Potent, selective AQP3 inhibitor; IC50 ~0.1-0.4 μM; less effective on AQP7, AQP9.</p>Fórmula:C11H7Cl2N3O3SPureza:99.53% - 99.53%Cor e Forma:SolidPeso molecular:332.16Ru-32514
CAS:Ru-32514 is a benzodiazepine receptor agonist.Fórmula:C18H17N3O2Pureza:99.21%Cor e Forma:SolidPeso molecular:307.35
