Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(93 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(64 produtos)
- Receptor CGRP(52 produtos)
- Canais de Cálcio(496 produtos)
- Canal de cloreto(49 produtos)
- Receptor GABA(337 produtos)
- Transportador de monoamina(23 produtos)
- Transportador de monocarboxilato(17 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(8 produtos)
- OAT(27 produtos)
- OCT(7 produtos)
- P-gp(53 produtos)
- Canal de Potássio(277 produtos)
- Bomba de prótons(39 produtos)
- SGLT(30 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(93 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2293 produtos de "Transportador de Membranas/Canal Iónico"
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XE991
CAS:<p>XE991 is a Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1) and M-current and can be used in the study of neurological disorders.</p>Fórmula:C26H20N2OPureza:98.87%Cor e Forma:SolidPeso molecular:376.45Golexanolone
CAS:Golexanolone can be used to study neurological diseases.Fórmula:C21H31NO2Pureza:99.90% - 99.99%Cor e Forma:SolidPeso molecular:329.48TWIK-1/TREK-1-IN-3
CAS:<p>TWIK-1/TREK-1-IN-3 is a potassium channel TREK-1 inhibitor TWIK-1/TREK-1-IN-3 has antidepressant activity and can be used to study depression.</p>Fórmula:C19H27F3N2O2Pureza:99.04%Cor e Forma:SolidPeso molecular:372.43WY-47766
CAS:<p>WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.</p>Fórmula:C14H13N3O2SPureza:97.63% - 99.83%Cor e Forma:SolidPeso molecular:287.34VU 0240551
CAS:VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.Fórmula:C16H14N4OS2Pureza:99.9%Cor e Forma:SolidPeso molecular:342.44DMCM hydrochloride
CAS:<p>DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine.</p>Fórmula:C17H19ClN2O4Pureza:99.56%Cor e Forma:SolidPeso molecular:350.8UCCF-853
CAS:<p>UCCF-853 是一种小分子 CFTR 调节剂，可用于研究囊性纤维化。</p>Fórmula:C14H8ClF3N2OPureza:99.82%Cor e Forma:SolidPeso molecular:312.67FR183998 free base
CAS:<p>FR183998 free base is an inhibitor of Na+/Ca2+ Exchanger.</p>Fórmula:C17H19Cl2N5O2SPureza:99.61%Cor e Forma:SolidPeso molecular:428.34NS-2710
CAS:<p>NS-2710, a GABA receptor agonist, is used potentially for the treatment of anxiety.</p>Fórmula:C22H20N4OPureza:99.7% - 99.82%Cor e Forma:SolidPeso molecular:356.42Sarmazenil
CAS:<p>Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor and is used in the study of chronic hepatic encephalopathy.</p>Fórmula:C15H14ClN3O3Pureza:99.46%Cor e Forma:SolidPeso molecular:319.74R(+)-IAA-94
CAS:<p>R(+)-IAA-94 (Methylindazone) blocks epithelial chloride channels; inhibits Nef-sdAb19 binding.</p>Fórmula:C17H18Cl2O4Pureza:98.95% - 99.17%Cor e Forma:SolidPeso molecular:357.23TC-N 1752
CAS:TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities.Fórmula:C25H27F3N6O3Pureza:99.71%Cor e Forma:SolidPeso molecular:516.52Olvanil
CAS:<p>Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.</p>Fórmula:C26H43NO3Pureza:99.58%Cor e Forma:SolidPeso molecular:417.62Ro 25-6981
CAS:<p>Ro 25-6981: potent, selective NMDA receptor blocker (NR2B), IC50: 0.009 μM (NR1C/NR2B), 52 μM (NR1C/NR2A), useful in Parkinson's research.</p>Fórmula:C22H29NO2Pureza:99.88%Cor e Forma:SolidPeso molecular:339.47VRT-532
CAS:<p>VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects.</p>Fórmula:C16H14N2OPureza:99.88% - 99.93%Cor e Forma:SolidPeso molecular:250.3CFTR corrector 8
CAS:<p>CFTR corrector 8: potent for cystic fibrosis research, modulates CFTR protein.</p>Fórmula:C29H27F2NO7Pureza:99.57%Cor e Forma:SolidPeso molecular:539.52Mavatrep
CAS:<p>Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.</p>Fórmula:C25H21F3N2OPureza:98.51% - 99.31%Cor e Forma:SolidPeso molecular:422.44Dasolampanel
CAS:Dasolampanel (NGX-426) is an ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders.Fórmula:C17H20ClN5O3Pureza:98.70%Cor e Forma:SolidPeso molecular:377.83Saripidem
CAS:<p>Saripidem (SL-85.0274) is a compound with anxiolytic activity.</p>Fórmula:C19H20ClN3OPureza:99.45%Cor e Forma:SolidPeso molecular:341.83Butibufen
CAS:Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.Fórmula:C14H20O2Pureza:98.11% - 98.91%Cor e Forma:SolidPeso molecular:220.31UCL 2077
CAS:<p>UCL 2077 blocks KCNQ channels, related to epilepsy, and selective slow-afterhyperpolarization channels, with 500 nM IC50, sparing Ca2+ channels.</p>Fórmula:C25H22N2Pureza:99.58%Cor e Forma:SolidPeso molecular:350.46MSP3
CAS:<p>MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.</p>Fórmula:C16H19NO3SPureza:99.89%Cor e Forma:SolidPeso molecular:305.39Nelonemdaz
CAS:Nelonemdaz (Neu2000) is an NMDA receptor antagonist with antioxidant activity that can be used to study cerebral infarction reperfusion injury.Fórmula:C15H8F7NO3Pureza:99.52%Cor e Forma:SolidPeso molecular:383.22ELB-139
CAS:<p>ELB-139 is a GABA A receptor agonist. ELB139 increases 5-HT in the striatum and prefrontal cortex of rats.</p>Fórmula:C14H16ClN3OPureza:>99.99%Cor e Forma:SolidPeso molecular:277.75GNE-8324
CAS:<p>GNE-8324 is a GluN2A selective positive allosteric modulator that enhances NMDAR-mediated synaptic responses in inhibitory, but not excitatory, neurons.</p>Fórmula:C18H18FN3OSPureza:98.68% - 99.34%Cor e Forma:SolidPeso molecular:343.42Enecadin
CAS:Enecadin is a neuroprotective agent.Fórmula:C21H28FN3OPureza:98.53%Cor e Forma:SolidPeso molecular:357.46UK 66914
CAS:<p>UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias.</p>Fórmula:C18H24N4O3SPureza:99.75%Cor e Forma:SolidPeso molecular:376.47Protonstatin-1
CAS:<p>Protonstatin-1: treats hypoglycemia & Alzheimer's, inhibits IGFIR kinase, used in cancer studies.</p>Fórmula:C8H5NO2S2Pureza:99.77%Cor e Forma:SolidPeso molecular:211.26FEMA-4809
CAS:<p>FEMA-4809 activates TRPM8, the ion channel for cold sensation, and is used as a cooling agent.</p>Fórmula:C17H17N3O2SPureza:99.9%Cor e Forma:SolidPeso molecular:327.4Transcainide
CAS:Transcainide (R 54718), an oral lidocaine-like antiarrhythmic, blocks BTX-activated Na+ channels in heart/muscle.Fórmula:C22H35N3O2Pureza:99.81%Cor e Forma:SolidPeso molecular:373.53Cerebrocrast
CAS:<p>Cerebrocrast (IOS-11212) has anti-inflammatory and hypoglycemic activity, blocks human platelet activation, and is used in the study of diabetes.</p>Fórmula:C26H35F2NO7Pureza:99.71%Cor e Forma:SolidPeso molecular:511.56Delucemine Hydrochloride
CAS:<p>Delucemine Hydrochloride (Delucemine) is a polyamine NMDA receptor antagonist used in the study of neurological disorders such as depression.</p>Fórmula:C16H18ClF2NPureza:98.49% - 99.30%Cor e Forma:SolidPeso molecular:297.77Muscimol HBr
CAS:Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.Fórmula:C4H7BrN2O2Pureza:98.13%Cor e Forma:Off-White PowderPeso molecular:195.01Neboglamine hydrochloride
CAS:Neboglamine (CR-2249, XY-2401) hydrochloride boosts NMDA receptor, aids schizophrenia research, and is orally active.Fórmula:C13H25ClN2O3Pureza:99.19%Cor e Forma:SolidPeso molecular:292.8Fengabine
CAS:<p>Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression.</p>Fórmula:C17H17Cl2NOPureza:99%Cor e Forma:SolidPeso molecular:322.23HC-070
CAS:HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).Fórmula:C22H20Cl2N4O4Pureza:98.48%Cor e Forma:SolidPeso molecular:475.32Abeprazan hydrochloride
CAS:<p>Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase</p>Fórmula:C19H18ClF3N2O3SPureza:98.57%Cor e Forma:SolidPeso molecular:446.87RL648_81
CAS:<p>RL648_81 is a selective activator of KCNQ2/3 channels (EC50 = 190 nM). RL648_81 can be used in studies about neuronal hyperexcitability neurologic disorders.</p>Fórmula:C17H17F4N3O2Pureza:99.82%Cor e Forma:SolidPeso molecular:371.33NC-1300-B
CAS:NC-1300-B inhibits H(+)-K(+)-ATPase and is used in the study of gastric ulcers.Fórmula:C17H19N3OSPureza:99.50%Cor e Forma:SolidPeso molecular:313.42Nerisopam
CAS:<p>Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.</p>Fórmula:C18H19N3O2Pureza:97.07%Cor e Forma:SolidPeso molecular:309.36FR-167356
CAS:<p>FR-167356 inhibits a3 isoform H⁺-ATPase (IC50: 170-370 nM), targeting osteoclasts, kidneys, macrophages; reduces B16-F10 bone metastasis.</p>Fórmula:C19H17Cl2NO3Pureza:98.44% - 99.74%Cor e Forma:SolidPeso molecular:378.25TASK-1-IN-1
CAS:<p>TASK-1-IN-1: Potent, selective TASK-1 blocker (IC50: 148 nM), weaker on TASK-3 (IC50: 1750 nM), anticancer properties.</p>Fórmula:C22H20N2O2Pureza:99.57%Cor e Forma:SoildPeso molecular:344.41Losigamone
CAS:Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures.Fórmula:C12H11ClO4Pureza:99.98%Cor e Forma:SolidPeso molecular:254.67NNC 05-711
CAS:<p>NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.</p>Fórmula:C21H23ClN2O3Pureza:99.92%Cor e Forma:SolidPeso molecular:386.87NaV1.2/1.6 channel blocker-1
CAS:<p>NaV1.2/1.6 channel blocker-1 is a NaV1.2/1.6 channel blocker that inhibits rNaV1.6 and can be used to study generalised epilepsy and movement disorders.</p>Fórmula:C14H14N2OSPureza:99.54%Cor e Forma:SolidPeso molecular:258.34SKF96067
CAS:<p>SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.</p>Fórmula:C21H22N2O2Pureza:99.89%Cor e Forma:SolidPeso molecular:334.41Bamocaftor
CAS:<p>Bamocaftor corrects CFTR in CF, restoring F508del-CFTR function, used with tezacaftor and VX-561 for F508del/MF patients.</p>Fórmula:C28H32F3N5O4SPureza:99.71%Cor e Forma:SolidPeso molecular:591.65Lirequinil
CAS:<p>Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.</p>Fórmula:C26H25ClN2O3Pureza:98.54%Cor e Forma:SolidPeso molecular:448.94Elismetrep
CAS:<p>Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.</p>Fórmula:C27H21F3N2O5SPureza:99.37% - 99.93%Cor e Forma:SolidPeso molecular:542.53Aptiganel
CAS:<p>Aptiganel (CNS-1102) is a non-competitive NMDA antagonist, a peptide that may be used to study acute ischemic stroke.</p>Fórmula:C20H21N3Pureza:98.13% - 98.90%Cor e Forma:SolidPeso molecular:303.4
