Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(93 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(64 produtos)
- Receptor CGRP(52 produtos)
- Canais de Cálcio(496 produtos)
- Canal de cloreto(49 produtos)
- Receptor GABA(336 produtos)
- Transportador de monoamina(23 produtos)
- Transportador de monocarboxilato(17 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(8 produtos)
- OAT(27 produtos)
- OCT(7 produtos)
- P-gp(53 produtos)
- Canal de Potássio(277 produtos)
- Bomba de prótons(39 produtos)
- SGLT(30 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(93 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2290 produtos de "Transportador de Membranas/Canal Iónico"
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KT-362 fumarate
CAS:<p>KT-362 fumarate, a novel antagonist of Ca, K, and Na channels, induces vasodilation and relaxes rabbit arterial strips.</p>Fórmula:C26H32N2O7SPureza:99.75% - 99.98%Cor e Forma:SolidPeso molecular:516.61ZM 226600
CAS:<p>ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.</p>Fórmula:C16H14F3NO4SPureza:99.87%Cor e Forma:SolidPeso molecular:373.35Leminoprazole
CAS:<p>Leminoprazole is an orally available H+,K(+)-ATPase inhibitor that protects gastric mucosal cells from various cellular damages.</p>Fórmula:C19H23N3OSPureza:99.08% - 99.56%Cor e Forma:SolidPeso molecular:341.47PD-118057
CAS:<p>PD-118057, a potent hERG activator, may treat long QT syndrome and heart failure without hERG activity inhibition.</p>Fórmula:C21H17Cl2NO2Pureza:99.16% - 99.97%Cor e Forma:SolidPeso molecular:386.27Orphenadrine
CAS:<p>Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,</p>Fórmula:C18H23NOPureza:98.91% - 99.11%Cor e Forma:SolidPeso molecular:269.38ANO1-IN-1
CAS:<p>ANO1-IN-1 blocks ANO1/2 channels (IC50: 2.56/15.43 μM) and hinders glioma cell growth.</p>Fórmula:C18H28N2O2SPureza:99.66%Cor e Forma:SolidPeso molecular:336.49BPDBA
CAS:BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 andFórmula:C19H20Cl2N2OPureza:99.43% - 99.95%Cor e Forma:SolidPeso molecular:363.28Coelenterazine h
CAS:<p>Coelenterazine H, a Ca2+ sensitive synthetic derivative, is a luminescent biomolecule used to measure Ca2+ changes.</p>Fórmula:C26H21N3O2Pureza:99.49%Cor e Forma:Yellow To Brownish PowderPeso molecular:407.46PF-06456384
CAS:PF-06456384 is a highly potent and selective NaV1.7 inhibitor with IC50 value of 0.01 nM.Fórmula:C35H32F3N7O3S2Pureza:98%Cor e Forma:SolidPeso molecular:719.8α,β-Methylene-ATP
CAS:<p>α,β-Methylene ATP，一种ATP的膦酸酯类似物，充当P2X3和P2X7受体的配体。该化合物对P2X1和P2X3表现出高选择性激动剂活性，而在P2X2, 4, 7受体上无活性。</p>Fórmula:C11H18N5O12P3Cor e Forma:SolidPeso molecular:505.21VU6007477
CAS:<p>VU6007477: M1 PAM, EC50=230 nM, min. agonist activity, penetrates CNS, no seizure AEs.</p>Fórmula:C24H26N6O2Cor e Forma:SolidPeso molecular:430.5BMS-199264 hydrochloride
CAS:<p>BMS-199264 hydrochloride is selective inhibitor of mitochondrial F1F0 ATP hydrolase,inhibit decline of ATP and myocardial necrosis during myocardial ischemia.</p>Fórmula:C26H32Cl2N4O4SPureza:99.86%Cor e Forma:SolidPeso molecular:567.53Glibornuride
CAS:<p>Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75).</p>Fórmula:C18H26N2O4SPureza:99.5%Cor e Forma:SolidPeso molecular:366.48Piprofurol
CAS:<p>Piprofurol is used as a Calcium channel blocker.</p>Fórmula:C26H33NO6Pureza:98%Cor e Forma:SolidPeso molecular:455.54URAT1 inhibitor 6
CAS:<p>URAT1 inhibitor 6 (Compound 1h), with an IC50 of 35 nM for hURAT1, demonstrates 200-fold and 8-fold greater potency compared to Lesinurad and Benzbromarone,</p>Fórmula:C9H7BrN3NaO2S2Cor e Forma:SolidPeso molecular:356.2RS 5773
CAS:<p>RS 5773 is a benzothiazepine derivative with antianginal effects.</p>Fórmula:C29H33ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:541.1PF-05241328
CAS:PF-05241328 is an effective and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (IC50: 31 nM).Fórmula:C19H21ClN4O4SPureza:98%Cor e Forma:SolidPeso molecular:436.91VMAT2-IN-I HCl
CAS:<p>VMAT2-IN-I HCl is an inhibitor of vesicular monoamine transporter-2. It also has 15- fold greater affinity than GZ- 793A.</p>Fórmula:C25H32ClF4NO4Pureza:98%Cor e Forma:SolidPeso molecular:521.97(Rac)-AMG8379
CAS:<p>(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.</p>Fórmula:C25H16ClF2N3O5SPureza:99.6%Cor e Forma:SolidPeso molecular:543.93PF-4778574
CAS:<p>PF-4778574 is a positive AMPA receptor allosteric modulation (EC50: 45 to 919 nM in different cells).</p>Fórmula:C19H22N2O3S2Pureza:98%Cor e Forma:SolidPeso molecular:390.52GNE-0723
CAS:<p>GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, GluN2A.blood-brain barrier (BBB) and Dravet syndrome and Alzheimer's disease (AD).</p>Fórmula:C16H8ClF6N5OSPureza:97.29% - 99.91%Cor e Forma:SolidPeso molecular:467.78PPADS tetrasodium
CAS:<p>PPADS tetrasodiuma is a P2X receptor antagonist and an inhibitor of the inverse mode of Na/Ca²⁺ exchange in guinea pig airway smooth muscle.</p>Fórmula:C14H10N3Na4O12PS2Pureza:95% - ≥95%Cor e Forma:SolidPeso molecular:599.3GDC-0310
CAS:<p>GDC-0310 is a selective, orally available Nav1.7 inhibitor with an IC50 of 0.6 nM for human Nav1.7, suitable for pain research.</p>Fórmula:C25H29Cl2FN2O4SPureza:99.877%Cor e Forma:SolidPeso molecular:543.48Chromanol 293B
CAS:slow delayed rectifier K+ current (IKs) blockerFórmula:C15H20N2O4SPureza:98%Cor e Forma:SolidPeso molecular:324.4α,β-Methylene ATP trisodium
CAS:α,β-Methylene ATP trisodium is a ligand of P2X3 and P2X7 receptor.Fórmula:C11H15N5Na3O12P3Pureza:99.66%Cor e Forma:SolidPeso molecular:571.15KVI-020
CAS:<p>KVI-020: oral Kv1.5 blocker (IC50: 480nM), hERG inhibitor (IC50: 15100nM), potent antiarrhythmic for AF studies.</p>Fórmula:C20H25N3O5SCor e Forma:SolidPeso molecular:419.49CGP 55845 hydrochloride
CAS:<p>CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].</p>Fórmula:C18H23Cl3NO3PCor e Forma:SolidPeso molecular:438.71ZM 260384
CAS:<p>ZM 260384 is a potassium channel opener.</p>Fórmula:C15H11F4N3O4Cor e Forma:SolidPeso molecular:373.26Lingdolinurad
CAS:<p>Lingdolinurad is a uric acid transporter protein inhibitor targeting hURAT1 for the study of hyperuricemia or gout.</p>Fórmula:C17H12BrN3O2Pureza:96.26%Cor e Forma:SolidPeso molecular:370.2(R)-Elexacaftor
CAS:<p>(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.</p>Fórmula:C26H34F3N7O4SPureza:98.991%Cor e Forma:SolidPeso molecular:597.65Aneratrigine
CAS:<p>Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].</p>Fórmula:C19H20ClF2N5O2S2Pureza:98%Cor e Forma:SolidPeso molecular:487.97DPO-1
CAS:<p>DPO-1 可以高效抑制电压门控钾离子通道Kv1.5，也可以阻断超快速延迟整流钾电流。它能够预防房性心律失常。</p>Fórmula:C22H29OPPureza:99.78%Cor e Forma:SolidPeso molecular:340.44Kv3 modulator 4
CAS:<p>Kv3 modulator 4 is a Kv3.1 (pEC50=5.45) and Kv3.2 modulator .Cyclobutyl structure.</p>Fórmula:C20H24N2O4Pureza:98%Cor e Forma:SolidPeso molecular:356.42Linaprazan
CAS:<p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>Fórmula:C21H26N4O2Pureza:99.54%Cor e Forma:SolidPeso molecular:366.46CP-409092
CAS:<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Fórmula:C17H19N3O2Pureza:98%Cor e Forma:SolidPeso molecular:297.35(R)-3,4-DCPG
CAS:<p>AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors</p>Fórmula:C10H9NO6Pureza:98%Cor e Forma:SolidPeso molecular:239.18Sudoterb free base
CAS:<p>Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate.</p>Fórmula:C29H28F3N5OPureza:97.26% - 98.85%Cor e Forma:SolidPeso molecular:519.56OADS
CAS:<p>OADS is an inhibitor of ClC-ec1 with low micromolar affinity. OADS has no specific effect on a CLC channel (ClC-1).</p>Fórmula:C30H42N2O8S2Cor e Forma:SolidPeso molecular:622.79CP 154526
CAS:<p>CRF1 receptor antagonist</p>Fórmula:C23H33ClN4Pureza:98%Cor e Forma:SolidPeso molecular:400.99Dasolampanel etibutil
CAS:<p>Dasolampanel etibutil is a novel selective antagonist of ionotropic glutamate receptor 5 (iGluR5).</p>Fórmula:C23H32ClN5O3Cor e Forma:SolidPeso molecular:461.98Potassium Channel Activator 1
CAS:<p>Potassium Channel Activator 1 aids treatment of ADHD, schizophrenia, and mood disorders by targeting the dopaminergic system.</p>Fórmula:C19H23N3O3Pureza:99.86%Cor e Forma:SolidPeso molecular:341.4UBP316
CAS:GluR5-containing kainate receptor antagonistFórmula:C20H19N3O6SPureza:98%Cor e Forma:SolidPeso molecular:429.45Naltiazem
CAS:<p>Naltiazem, a calcium channel antagonist, is used potentially for the treatment of arrhythmias, hypertension and myocardial infarction.</p>Fórmula:C26H28N2O4SPureza:98%Cor e Forma:SolidPeso molecular:464.58Xeniafaraunol A
CAS:<p>Xeniafaraunol A (compound 31) is a potent inhibitor of the transient receptor potential melastatin 7 (TRPM7) channel [1].</p>Fórmula:C20H28O2Cor e Forma:SolidPeso molecular:300.44TROX-1
CAS:<p>TROX-1 is the activation state-dependent Cav2 channel antagonist.</p>Fórmula:C22H16ClFN6OPureza:98%Cor e Forma:SolidPeso molecular:434.85MK-2295
CAS:<p>MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment of chronic pain.</p>Fórmula:C27H31FN6O2Pureza:98.83% - 99.44%Cor e Forma:SolidPeso molecular:490.57TRPV2-selective blocker 1
CAS:<p>TRPV2-selective blocker 1 (compound IV2-1) is a selective inhibitor of the TRPV2 channel, exhibiting an IC50 value of 6.3 μM.</p>Fórmula:C15H18OS2Cor e Forma:SolidPeso molecular:278.43AMPA receptor modulator-2
CAS:<p>AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.</p>Fórmula:C15H6F6N4OSPureza:99.8%Cor e Forma:SolidPeso molecular:404.29BTG 502
CAS:<p>BTG 502 is an alkylamide insecticide that binds to voltage-gated sodium channels, antagonising the activation of sodium channels by Batrachotoxin (BTX).</p>Fórmula:C21H24BrNOPureza:99.30%Cor e Forma:SolidPeso molecular:386.33XR9051
CAS:<p>XR9051, a synthetic derivative of a natural compound, potently reverses P-glycoprotein MDR (EC50 = 1.4 nM) by inhibiting cytotoxic binding.</p>Fórmula:C39H38N4O5Cor e Forma:SolidPeso molecular:642.74
