Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(93 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(64 produtos)
- Receptor CGRP(52 produtos)
- Canais de Cálcio(496 produtos)
- Canal de cloreto(49 produtos)
- Receptor GABA(336 produtos)
- Transportador de monoamina(23 produtos)
- Transportador de monocarboxilato(17 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(8 produtos)
- OAT(27 produtos)
- OCT(7 produtos)
- P-gp(53 produtos)
- Canal de Potássio(277 produtos)
- Bomba de prótons(39 produtos)
- SGLT(30 produtos)
- Canal de Sódio(202 produtos)
- Canal TRP/TRPV(93 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2290 produtos de "Transportador de Membranas/Canal Iónico"
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Ritivixibat
CAS:<p>Ritivixibat inhibits IBAT and modulates bile acids, used in research for cardiovascular, metabolic, GI, and liver diseases.</p>Fórmula:C26H36N2O5S2Cor e Forma:SolidPeso molecular:520.7ADCI
CAS:<p>ADCI inhibits voltage-activated sodium and NMDA channels; boosts dopamine metabolism in prefrontal cortex and nucleus accumbens.</p>Fórmula:C16H14N2OPureza:98%Cor e Forma:SolidPeso molecular:250.3(-)-Bicuculline methochloride
CAS:<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Fórmula:C21H20ClNO6Pureza:98%Cor e Forma:SolidPeso molecular:417.84CGP 54626 hydrochloride
CAS:<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Fórmula:C18H29Cl3NO3PPureza:98%Cor e Forma:SolidPeso molecular:444.76BMT-108908
CAS:<p>BMT-108908 is a Negative Allosteric Modulator. It is selective for the NR2B Subtype of The NMDA Receptor Impair Cognition in Multiple Domains.</p>Fórmula:C22H25FN2O2Cor e Forma:SolidPeso molecular:368.44Y-27152
CAS:<p>Y-27152 is a prodrug of the KATP (Kir6) channel opener Y-26763 and is a long-acting K+ channel opener.</p>Fórmula:C21H22N2O4Pureza:98%Cor e Forma:SolidPeso molecular:366.41URAT1 inhibitor 1
CAS:URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.Fórmula:C19H15Br2N5O2S2Pureza:98%Cor e Forma:SolidPeso molecular:569.29MK-8153
CAS:<p>MK-8153: Selective, potent ROMK inhibitor, orally active, IC50: ROMK EP 5 μM, hERG EP 34 μM; potential diuretic.</p>Fórmula:C24H28N2O6Cor e Forma:SolidPeso molecular:440.4911-deoxy-PGF2a
CAS:<p>11-deoxy-PGF2a is a thromboxane A2 receptor agonist that partially alleviates crowding in Lpar3(−/−) female embryos and induces smooth muscle contraction</p>Fórmula:C20H34O4Cor e Forma:SolidPeso molecular:338.48Zelquistinel
CAS:<p>Zelquistinel, an NMDA receptor agonist, aids research on depression, anxiety, and psychiatric disorders.</p>Fórmula:C15H25N3O5Cor e Forma:SolidPeso molecular:327.38APS3
CAS:<p>APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].</p>Fórmula:C18H7Cl2F6N5O5S2Cor e Forma:SolidPeso molecular:622.31JYL-1511
CAS:<p>JYL-1511 is the TRPV1 channel partial agonist.</p>Fórmula:C21H29N3O3S2Pureza:98%Cor e Forma:SolidPeso molecular:435.6GABAA receptor agent 2 TFA
CAS:<p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>Fórmula:C22H22F3N3O3Cor e Forma:SolidPeso molecular:433.42ARN 11391
CAS:<p>ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ion</p>Fórmula:C22H29N3O3Cor e Forma:SolidPeso molecular:383.49D-erythro-Sphingosine hydrochloride
CAS:<p>D-erythro-Sphingosine HCl activates TRPM3 and dephosphorylates retinoblastoma protein.</p>Fórmula:C18H38ClNO2Cor e Forma:SolidPeso molecular:335.95γ-Kainylglutamic acid
CAS:<p>gamma-Kainylglutamic acid is a selective amino acid-induced neuroexcitation antagonist.</p>Fórmula:C15H22N2O7Pureza:98%Cor e Forma:SolidPeso molecular:342.34FGIN-1-27
CAS:<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Fórmula:C28H37FN2OPureza:99.86%Cor e Forma:SolidPeso molecular:436.6AR-C141990
CAS:<p>AR-C141990 is a lactate transporters inhibitor.</p>Fórmula:C26H28N4O4SCor e Forma:SolidPeso molecular:492.59BMS-986169
CAS:<p>BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, depression.</p>Fórmula:C23H27FN2O2Pureza:97.61%Cor e Forma:SolidPeso molecular:382.47A 425619
CAS:<p>A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist</p>Fórmula:C18H14F3N3OPureza:99.75%Cor e Forma:SolidPeso molecular:345.32Mioflazine
CAS:<p>Mioflazine suppresses nucleoside uptake. Mioflazine is an orally active nucleoside transport inhibitor. It has the potential for sleep disorders treatment.</p>Fórmula:C29H30Cl2F2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:575.48U 89843A
CAS:<p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>Fórmula:C16H23N5Pureza:99.62%Cor e Forma:SolidPeso molecular:285.39S-Pantoprazole sodium trihydrate
CAS:<p>S-Pantoprazole (sodium trihydrate), a variant of Pantoprazole, is pivotal in managing diseases associated with gastric acid secretion disorders, serving as a</p>Fórmula:C16H20F2N3NaO7SPureza:98%Cor e Forma:SolidPeso molecular:459.4GMA-839
CAS:<p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>Fórmula:C21H31F3O3Pureza:98%Cor e Forma:SolidPeso molecular:388.46AGN-201904Z
CAS:<p>AGN-201904Z is a slow-release, acid-resistant pro-PPI that turns into omeprazole, offering extended acid suppression.</p>Fórmula:C25H25N3NaO8S2Pureza:98%Cor e Forma:SolidPeso molecular:582.6AC-4
CAS:<p>AC-4 is a blocker of photoswitchable TRPV1 channel.</p>Fórmula:C26H25F3N4O2SCor e Forma:SolidPeso molecular:514.56Nepaprazole
CAS:<p>Nepaprazole (TY-11345) is a potent proton pump inhibitor; IC50: 5.8µM at pH 6.0, 9.9µM at pH 7.4. Better inhibition in weak acid.</p>Fórmula:C18H19N3O2SPureza:98%Cor e Forma:SolidPeso molecular:341.43P-1075
CAS:<p>P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.</p>Fórmula:C12H17N5Pureza:99.85%Cor e Forma:SolidPeso molecular:231.33′-Acetate-ATP
CAS:<p>3’-Acetate-ATP, an analogue of ATP and its acetylation product, exhibits maximum ultraviolet absorption at 259 nm in neutral aqueous solutions.</p>Fórmula:C12H18N5O14P3Cor e Forma:SolidPeso molecular:549.22NCS-382 sodium
CAS:<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Fórmula:C13H13NaO3Pureza:98%Cor e Forma:SolidPeso molecular:240.23NPEC-caged-(S)-AMPA
CAS:<p>AMPA receptor agonist</p>Fórmula:C16H17N3O8Pureza:98%Cor e Forma:SolidPeso molecular:379.32TRPC3/6-IN-2
CAS:<p>TRPC3/6-IN-2 is a potent inhibitor of TRPC3 and TRPC6, exhibiting IC50 values of 16 nM for TRPC3 and 29.8 nM for TRPC6, respectively [1].</p>Fórmula:C18H23F2N5Cor e Forma:SolidPeso molecular:347.41L 663581
CAS:<p>L 663581 is the benzodiazepine receptor partial agonist.</p>Fórmula:C17H16ClN5O2Pureza:98%Cor e Forma:SolidPeso molecular:357.79TPA 023
CAS:<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Fórmula:C20H22FN7OPureza:99.75%Cor e Forma:SolidPeso molecular:395.43Kv3 modulator 2
CAS:<p>Kv3 modulator 2 is a potent Kv3 channels modulator.has analgesic activity and is used in the prophylaxis or treatment of related disorders.</p>Fórmula:C21H21N3O4Pureza:98%Cor e Forma:SolidPeso molecular:379.41SLC13A5-IN-1
CAS:<p>SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5),completely blocks the uptake of 14C-citrate(IC50 : 0.022 μM in HepG2 cells).</p>Fórmula:C19H19Cl3N2O3SPureza:99.67%Cor e Forma:SolidPeso molecular:461.79TRPC5-IN-3
CAS:<p>TRPC5-IN-3 is a potent TRPC5 inhibitor (IC50= 10.75 nM).</p>Fórmula:C18H15ClF3N5OCor e Forma:SolidPeso molecular:409.79VU0463271
CAS:<p>VU0463271: KCC2 antagonist, IC50 61 nM, >100x selective over NKCC1, inactive on other GPCRs, channels, transporters.</p>Fórmula:C19H18N4OS2Pureza:97.84% - 99.55%Cor e Forma:SolidPeso molecular:382.5Pristinamycin IA
CAS:<p>Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic.</p>Fórmula:C45H54N8O10Pureza:97.44%Cor e Forma:SolidPeso molecular:866.96DNDS
CAS:<p>DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).</p>Fórmula:C14H8N2Na2O10S2Pureza:99.92%Cor e Forma:Physical Description White Powder (Ntp 1992)Peso molecular:474.33NS1219
CAS:<p>NS1219, an isomer of NS1209, is a selective AMPA antagonist for studying stroke, neuropathic pain, and epilepsy.</p>Fórmula:C24H28N4O7SCor e Forma:SolidPeso molecular:516.57Sodium Channel inhibitor 4
CAS:<p>Sodium Channel Inhibitor 4 is a compound that functions as a sodium channel inhibitor [1].</p>Fórmula:C19H18ClN3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:451.95PF 04531083
CAS:<p>PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.</p>Fórmula:C17H16ClN5O2Pureza:99.85%Cor e Forma:SolidPeso molecular:357.79(+)-Bicuculline methiodide
CAS:<p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>Fórmula:C21H20INO6Pureza:99.24%Cor e Forma:SolidPeso molecular:509.29Budiodarone
CAS:<p>Budiodarone (ATI-2042) resembles amiodarone, potentially preventing atrial fibrillation.</p>Fórmula:C27H31I2NO5Cor e Forma:SolidPeso molecular:703.35Piperidine-4-sulfonic acid
CAS:<p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>Fórmula:C5H11NO3SPureza:98%Cor e Forma:SolidPeso molecular:165.216,2'-Dihydroxyflavone
CAS:<p>6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.</p>Fórmula:C15H10O4Pureza:99.44% - 99.67%Cor e Forma:SolidPeso molecular:254.24PHP 501 trifluoroacetate
CAS:<p>GABAA antagonist</p>Fórmula:C20H21N3OPureza:98%Cor e Forma:SolidPeso molecular:319.4ML-252 hydrochloride
CAS:<p>ML-252 is a potent, selective inhibitor of the Kv7.2 voltage-gated potassium channel, demonstrating an IC50 value of 69 nM in patch clamp assays. It exists as the (S)-enantiomer, which is significantly more effective than both its (R)-enantiomer counterpart and the racemic mixture, with respective IC50 values of 944 nM and 160 nM. ML-252 exhibits high selectivity for Kv7.2 over other potassium channel subtypes and shows minimal activity against more than 68 G protein-coupled receptors, various transporters, L- and N-type calcium channels, K_ATP, and hERG potassium channels. However, it does inhibit the melatonin MT1 receptor by 61% at a 10 µM concentration.</p>Fórmula:C20H24N2OHClCor e Forma:SolidPeso molecular:344.9JYL-273
CAS:<p>JYL-273 is a TRPV1 agonist.</p>Fórmula:C28H39NO4SCor e Forma:SolidPeso molecular:485.68
