Factor Xa
O fator Xa é uma enzima crucial na cascata de coagulação que converte a protrombina em trombina, levando à formação de coágulos sanguíneos. A inibição do fator Xa é uma estratégia terapêutica amplamente utilizada para prevenir e tratar distúrbios tromboembólicos, como trombose venosa profunda, embolia pulmonar e AVC. Na CymitQuimica, oferecemos inibidores do fator Xa para apoiar sua pesquisa em hematologia, saúde cardiovascular e terapia anticoagulante.
Foram encontrados 80 produtos de "Factor Xa"
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Rivaroxaban
CAS:<p>Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with thrombin formation.</p>Fórmula:C19H18ClN3O5SPureza:99.93% - >99.99%Cor e Forma:SolidPeso molecular:435.88Gabexate mesylate
CAS:<p>Gabexate mesylate (FOY) inhibits thrombin, plasmin, kallikrein; used for pancreatitis, DIC, hemodialysis anticoagulant.</p>Fórmula:C17H27N3O7SPureza:99.2% - 99.64%Cor e Forma:White CrystalPeso molecular:417.48Letaxaban
CAS:<p>Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.</p>Fórmula:C22H26ClN3O5SPureza:99.13% - 99.87%Cor e Forma:SolidPeso molecular:479.985-R-Rivaroxaban
CAS:<p>5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.</p>Fórmula:C19H18ClN3O5SPureza:99.75%Cor e Forma:SolidPeso molecular:435.88Osocimab
CAS:<p>Osocimab (BAY 1213790) is a strong FXIa inhibitor, Ki 2.4 nM, EC50 0.2 nM, and reduces thrombosis in research.</p>Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:144.46 kDa2-Methoxyphenothiazine
CAS:<p>2-Methoxy Phenothiazine is light yellow or light gray solid.</p>Fórmula:C13H11NOSPureza:99.28%Cor e Forma:Orange Yellow Crystal PowderPeso molecular:229.3Ciraparantag acetate
CAS:<p>Ciraparantag acetate reverses anticoagulation, binding heparins and DOACs noncovalently.</p>Fórmula:C24H52N12O4Pureza:99.65%Cor e Forma:SolidPeso molecular:572.75Garadacimab
CAS:<p>Garadacimab (CSL312) is a human IgG4 antibody against FXIIa, used to research hereditary angioedema.</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Cor e Forma:LiquidPeso molecular:146.5 kDaCanine Factor Xa
<p>CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.</p>Cor e Forma:Odour SolidD-Pro-Phe-Arg-Chloromethylketone
CAS:<p>D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammation</p>Fórmula:C21H31ClN6O3Pureza:98%Cor e Forma:SolidPeso molecular:450.96FXIa-IN-15
CAS:<p>FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.</p>Fórmula:C32H23ClF3N7O4Cor e Forma:SolidPeso molecular:662.02CH3OCO-D-CHA-Gly-Arg-pNA acetate
CAS:<p>CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].</p>Fórmula:C27H42N8O9Pureza:98%Cor e Forma:SolidPeso molecular:622.67O-Desmethyl apixaban sulfate sodium
<p>O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.</p>Fórmula:C24H22N5NaO7SPureza:98%Cor e Forma:SolidPeso molecular:547.52Edoxaban Isomer
CAS:<p>Edoxaban Isomer is an impurity of Edoxaban, which is a novel inhibitor of factor Xa.</p>Fórmula:C24H30ClN7O4SCor e Forma:SolidPeso molecular:548.06FXIIa-IN-1 HCl
CAS:<p>FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.</p>Fórmula:C21H17ClN2O6Pureza:99.61%Cor e Forma:SoildPeso molecular:428.82Boc-Ile-Glu-Gly-Arg-AMC
CAS:<p>Boc-IEGR-AMC: fluorogenic substrate for factor Xa and Halocynthia roretzi acrosin.</p>Fórmula:C34H50N8O10Pureza:98%Cor e Forma:White PowderPeso molecular:730.81Edoxaban impurity 6
CAS:<p>Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.</p>Fórmula:C16H22ClN5O3Cor e Forma:SolidPeso molecular:367.83Lofacimig
<p>Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.</p>Cor e Forma:Odour LiquidRabbit Factor Xa
<p>RabbitFactor Xa is produced from purified Rabbit Factor X through activation by Russells' Viper Venom, followed by the removal of the venom.</p>Cor e Forma:Odour SolidMethoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS:<p>Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3</p>Fórmula:C22H34N8O7Cor e Forma:SolidPeso molecular:522.55cMCoFx1
CAS:<p>cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.</p>Fórmula:C146H232N52O44S6Cor e Forma:SolidPeso molecular:3612.12Naroparcil
CAS:<p>Naroparcil, an oral thioglycoside, has antithrombotic properties and alters thrombin complex formation.</p>Fórmula:C19H17NO4S2Pureza:98.71% - 99.88%Cor e Forma:SolidPeso molecular:387.47FXIIa-IN-4
<p>FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.</p>Fórmula:C11H9FN4O3Peso molecular:264.06587Concizumab
CAS:<p>Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking the</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:145.76 kDaAsundexian
CAS:<p>Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,</p>Fórmula:C26H21ClF4N6O4Pureza:99.89% - 99.90%Cor e Forma:SolidPeso molecular:592.93Rat Factor Xa
<p>RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.</p>Cor e Forma:Odour SolidPorcine Factor Xa
CAS:<p>PorcineFactor Xa is obtained by activating purified Porcine Factor X using Russells' Viper Venom, after which the venom is removed.</p>Cor e Forma:SolidApixaban 13C,d3
CAS:<p>Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor Xa</p>Fórmula:C25H25N5O4Pureza:98%Cor e Forma:SolidPeso molecular:463.51Betrixaban-d6
CAS:<p>Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.</p>Fórmula:C23H22ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:457.95Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS:<p>Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.</p>Fórmula:C27H28N4O5Pureza:99.5%Cor e Forma:SolidPeso molecular:488.54Enoxaparin sodium
CAS:<p>Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.</p>Fórmula:C42H59N3Na4O35S2Pureza:98%Cor e Forma:SolidPeso molecular:1322Apixaban
CAS:<p>Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.</p>Fórmula:C25H25N5O4Pureza:99.73% - 99.93%Cor e Forma:SolidPeso molecular:459.5Edoxaban Tosylate Monohydrate
CAS:<p>Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.</p>Fórmula:C31H40ClN7O8S2Pureza:99.86% - 99.91%Cor e Forma:SolidPeso molecular:738.27BISMUTH SUBGALLATE
CAS:<p>Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.</p>Fórmula:C7H5BiO6Pureza:98.7%Cor e Forma:White To Yellow CrystalsPeso molecular:394.09Benzamidine hydrochloride
CAS:<p>Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.</p>Fórmula:C7H9ClN2Pureza:99.25% - 99.97%Cor e Forma:White To Off-White PowderPeso molecular:156.614-Chlorophenylurea
CAS:<p>4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.</p>Fórmula:C7H7ClN2OPureza:98.87%Cor e Forma:White Granular / PrillPeso molecular:170.6Darexaban
CAS:<p>Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.</p>Fórmula:C27H30N4O4Pureza:98.33%Cor e Forma:SolidPeso molecular:474.55Fondaparinux sodium
CAS:<p>Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.</p>Fórmula:C31H43N3Na10O49S8Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:1728.08Edoxaban hydrochloride
CAS:<p>Edoxaban (DU-176b) HCl: Oral, selective Factor Xa inhibitor, Ki 0.561 nM; prevents thromboembolic disease.</p>Fórmula:C24H31Cl2N7O4SCor e Forma:SolidPeso molecular:584.52Betrixaban hydrochloride(330942-05-7(free base))
<p>Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5</p>Fórmula:C23H23Cl2N5O3Pureza:99.54%Cor e Forma:SolidPeso molecular:488.36Heparin sodium salt
CAS:<p>Heparin sodium, a sulfated glycosaminoglycan, acts as an anticoagulant and inhibits exosome-cell interactions.</p>Fórmula:C26H42N2NaO37S5Pureza:98%Cor e Forma:SolidPeso molecular:1157.89Abelacimab
CAS:<p>NI-0801 (Anti-CXCL10 / IP-1) is a CHO-expressed humanized monoclonal antibody targeting CXCL10/IP-10 for the study of vitiligo and biliary cirrhosis.</p>Pureza:94.9% (SDS-PAGE); 99.1% (SEC-HPLC) - 94.9% (SDS-PAGE); 99.1% (SEC-HPLC)Cor e Forma:LiquidEdoxaban-d6
CAS:<p>Edoxaban-d6 is a deuterated compound of Edoxaban. Edoxaban has a CAS number of 480449-70-5. Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.</p>Fórmula:C24H24D6ClN7O4SCor e Forma:SolidPeso molecular:554.09Betrixaban maleate
CAS:<p>"Betrixaban, a non-vitamin K anticoagulant by Portola, inhibits factor Xa with low hERG affinity, preventing VTE in at-risk adults."</p>Fórmula:C27H26ClN5O7Pureza:99.46% - 99.86%Cor e Forma:SolidPeso molecular:567.98Rivaroxaban-d4
CAS:<p>Rivaroxaban-d4 is a deuterated marker of Rivaroxaban for isotopic tracing.BAY 59-7939 is a potent and selective direct inhibitor of coagulation factor Xa (FXa.</p>Fórmula:C19H18ClN3O5SPureza:98%Cor e Forma:SolidPeso molecular:439.91Betrixaban
CAS:<p>Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.</p>Fórmula:C23H22ClN5O3Pureza:99.33%Cor e Forma:SolidPeso molecular:451.91Milvexian
CAS:<p>Milvexian (BMS-986177) is an oral antithrombotic, reversibly inhibiting human/rabbit FXIa with K i of 0.11/0.38 nM.</p>Fórmula:C28H23Cl2F2N9O2Cor e Forma:SolidPeso molecular:626.45YM-75466
CAS:<p>YM-75466 is a factor Xa inhibitor reducing TAT in plasma dose-dependently without prolonging coagulation.</p>Fórmula:C28H35N5O8S2Cor e Forma:SolidPeso molecular:633.74Pegnivacogin
CAS:<p>Pegnivacogin is a coagulation factor IXa RNA aptamer inhibitor.</p>Fórmula:C20H40N3O11PPureza:98%Cor e Forma:SolidPeso molecular:529.52BMS 740808
CAS:<p>BMS-740808 is a highly effective and selective factor X inhibitor.</p>Fórmula:C31H27F3N6O3Cor e Forma:SolidPeso molecular:588.58Ciraparantag TFA
CAS:<p>Ciraparantag TFA reverses anticoagulants by inhibiting thrombin and factor Xa.</p>Fórmula:C26H50F6N12O6Pureza:98%Cor e Forma:SolidPeso molecular:740.74Ciraparantag
CAS:<p>Ciraparantag inhibits thrombin, factor Xa, and reverses various anticoagulants.</p>Fórmula:C22H48N12O2Pureza:98%Cor e Forma:SolidPeso molecular:512.7Darexaban glucuronide
CAS:<p>Darexaban glucuronide is the major component in plasma after oral administration of darexaban to humans. Darexaban (YM150) is a direct inhibitor of factor Xa.</p>Fórmula:C33H38N4O10Cor e Forma:SolidPeso molecular:650.68Tanogitran
CAS:<p>Tanogitran, a coagulation factor Xa inhibitor, is used potentially for the treatment of septic shock.</p>Fórmula:C25H31N7O3Pureza:98%Cor e Forma:SolidPeso molecular:477.56DPC-423
CAS:<p>DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis.</p>Fórmula:C25H21ClF4N4O3SPureza:98%Cor e Forma:SolidPeso molecular:568.97Razaxaban hydrochloride
CAS:<p>Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.</p>Fórmula:C24H21ClF4N8O2Pureza:98%Cor e Forma:SolidPeso molecular:564.92Otamixaban
CAS:<p>Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.</p>Fórmula:C25H26N4O4Pureza:98.08%Cor e Forma:SolidPeso molecular:446.5Eribaxaban
CAS:<p>Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.</p>Fórmula:C24H22ClFN4O4Pureza:98.99% - 99.13%Cor e Forma:SolidPeso molecular:484.91Fidexaban
CAS:<p>Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays</p>Fórmula:C25H24F2N6O5Pureza:98.64% - 99.43%Cor e Forma:SolidPeso molecular:526.49LY 517717
CAS:<p>LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).</p>Fórmula:C27H33N5O2Pureza:99.77% - 99.88%Cor e Forma:SolidPeso molecular:459.58Edoxaban
CAS:<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Fórmula:C24H30ClN7O4SPureza:97.67% - 99.71%Cor e Forma:SolidPeso molecular:548.06Zifaxaban
CAS:<p>Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.</p>Fórmula:C20H16ClN3O4SPureza:97.46% - 99.82%Cor e Forma:SolidPeso molecular:429.88BMS-262084
CAS:<p>BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.</p>Fórmula:C18H31N7O5Cor e Forma:SolidPeso molecular:425.48FXIa-IN-1
CAS:<p>FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.</p>Fórmula:C20H19F3N4O5Pureza:98%Cor e Forma:SolidPeso molecular:452.38Frunexian
CAS:<p>Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.</p>Fórmula:C19H26N4O4Pureza:98%Cor e Forma:SolidPeso molecular:374.43AS1468240
CAS:<p>AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.</p>Fórmula:C25H25Cl2N5O3Cor e Forma:SolidPeso molecular:514.4BI-11634
CAS:<p>BI-11634 is a factor Xa inhibitor.</p>Fórmula:C22H23ClN4NaO4Pureza:98%Cor e Forma:SolidPeso molecular:465.89BMS-962212
CAS:<p>BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.</p>Fórmula:C32H28ClFN8O5Pureza:98%Cor e Forma:SolidPeso molecular:659.07FXIa-IN-7
CAS:<p>FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.</p>Fórmula:C28H28N2O4Pureza:98.55%Cor e Forma:SolidPeso molecular:456.53BMS-654457
CAS:<p>BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).</p>Fórmula:C36H37N5O4Pureza:98%Cor e Forma:SolidPeso molecular:603.71FXa-IN-1
CAS:<p>FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.</p>Fórmula:C24H18F5N5OCor e Forma:SolidPeso molecular:487.42Dechloro Rivaroxaban
CAS:<p>Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.</p>Fórmula:C19H19N3O5SPureza:98.63%Cor e Forma:SolidPeso molecular:401.44DX-9065A HCl hydrate
CAS:<p>DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.</p>Fórmula:C26H39ClN4O8Pureza:98%Cor e Forma:SolidPeso molecular:571.06BAY 3389934
CAS:<p>BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.</p>Fórmula:C26H30ClN5O7S2Cor e Forma:SolidPeso molecular:624.129RWJ-445167
CAS:<p>RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.</p>Fórmula:C18H24N6O5SPureza:98%Cor e Forma:SolidPeso molecular:436.49FXIa-6f
CAS:<p>FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species</p>Fórmula:C31H29ClF2N4O4Cor e Forma:SolidPeso molecular:595.04FXIa-IN-6
CAS:<p>FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.</p>Fórmula:C31H29ClF2N4O4Cor e Forma:SolidPeso molecular:595.04FXIa-IN-9
CAS:<p>FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.</p>Fórmula:C23H18Cl2F3N9O2Cor e Forma:SolidPeso molecular:580.35FXIa-IN-8
<p>FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.</p>Cor e Forma:Solid5-Chlorothiophene-2-carboxylic acid
CAS:<p>5-Chlorothiophene-2-carboxylic acid [catalog number: T66447, CAS number: 24065-33-6] is a valuable organic compound for life sciences research.</p>Fórmula:C5H3ClO2SCor e Forma:SolidPeso molecular:162.59
