Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(2.949 produtos)
- Antibiótico(918 produtos)
- Antifecção(23 produtos)
- DHFR(32 produtos)
- Síntese de DNA/RNA(706 produtos)
- HBV(176 produtos)
- HIV Protease(447 produtos)
- HSV(91 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
Exibir 2 mais subcategorias
Foram encontrados 5832 produtos de "Microbiologia/Virologia"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
DprE1-IN-9
CAS:<p>DprE1-IN-9 (compound B18) is an efficient reversible inhibitor of DprE1, interacting with the enzyme's receptor cavity.</p>Fórmula:C22H25F3N4O2Cor e Forma:SolidPeso molecular:434.45Caerulomycin A
CAS:<p>Caerulomycin A (Caerulomycin) (Cerulomycin; Caerulomycin) is an antifungal compound.</p>Fórmula:C12H11N3O2Pureza:99.28%Cor e Forma:SolidPeso molecular:229.23Pexiganan acetate
CAS:<p>Pexiganan acetate (MSI 78), a 22-residue peptide analogue of magainin 2, disrupts bacterial membranes or walls, leading to antibacterial activity.</p>Fórmula:C122H210N32O22·xC2H4O2Pureza:99.88%Cor e Forma:SolidPeso molecular:2477.22 (free base)WRN inhibitor 5
CAS:<p>WRN Inhibitor 5 (Example 157), a cyclic vinyl sulfone-based compound, serves as an inhibitor of Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Fórmula:C23H20N2O6SCor e Forma:SolidPeso molecular:452.48Cefteram
CAS:<p>Cefteram (T-2525), an orally active ester of the cephalosporin class, is the free acid form of Cefteram pivoxil.</p>Fórmula:C16H17N9O5S2Cor e Forma:SolidPeso molecular:479.49Orysastrobin
CAS:<p>Orysastrobin, a "quinone outside inhibitor" (QoI) fungicide, demonstrates outstanding efficacy in controlling rice leaf and panicle blast as well as sheath</p>Fórmula:C18H25N5O5Cor e Forma:SolidPeso molecular:391.42ST-148 maleate
CAS:<p>ST-148 maleate, a potent and orally active DENV inhibitor, exhibits antiviral efficacy with low cell toxicity. It disrupts the interaction between lipid droplets and the C protein, inhibiting viral replication. [1]</p>Fórmula:C31H40N4O7SCor e Forma:SolidPeso molecular:612.74Urease-IN-6
CAS:<p>Urease-IN-6, a potent Urease inhibitor, exhibits an IC50 value of 14.2 μM and is utilized in the research of peptic and gastric ulcers [1].</p>Fórmula:C18H19N3OSCor e Forma:SolidPeso molecular:325.43N,O-Diacetyltyramine
CAS:<p>N,O-Diacetyltyramine, isolated from the actinomycete Pseudonocardia endophytica VUK-10, exhibits both antibacterial activity against Gram-positive and Gram-negative bacteria, alongside fungi, and demonstrates cytotoxicity towards MDA-MB-231, HeLa, MCF-7, and OAW-42 cells [1].</p>Fórmula:C12H15NO3Cor e Forma:SolidPeso molecular:221.25KY386
CAS:<p>KY386 is a potent and selective DHX33 helicase inhibitor with an IC50 value of 19 nM.</p>Fórmula:C21H19N5O2SCor e Forma:SolidPeso molecular:405.478-NH2-ATP tetrasodium
CAS:<p>8-NH2-ATP tetrasodium, an inactive ATP variant, originates from 8-NH2-Ado tetrasodium, which triggers the apoptosis-associated cleavage of poly (ADP-ribose) polymerase [1] [2].</p>Fórmula:C10H13N6Na4O13P3Cor e Forma:SolidPeso molecular:610.12Berkeleylactone E
CAS:<p>Berkeleylactone E, a macrolide antibiotic [1], exhibits antimicrobial properties.</p>Fórmula:C20H32O7Cor e Forma:SolidPeso molecular:384.469Inz-5
CAS:<p>Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.</p>Fórmula:C18H14F4N6Cor e Forma:SolidPeso molecular:390.34Zoxamide
CAS:<p>Zoxamide (RH-7281) is an oomycete-specific fungicide that impedes nuclear division in Phytophthora capsici germlings and disrupts the microtubule cytoskeleton [</p>Fórmula:C14H16Cl3NO2Cor e Forma:SolidPeso molecular:336.64β-Gal-NONOate
CAS:<p>Beta-gal-nonoate, a β-galactosidase dependent nitric oxide (NO) donor, releases NO upon activation by β-galactosidase. It exhibits bactericidal activity, thus serving as an effective bactericide [1].</p>Fórmula:C10H19N3O7Cor e Forma:SolidPeso molecular:293.27EDI048
CAS:<p>EDI048, also known as compound 1.16, is an orally active inhibitor of Cryptosporidium PI4K, utilized in the study of cryptosporidiosis [1].</p>Fórmula:C25H21ClN4O4Pureza:98%Cor e Forma:SolidPeso molecular:476.91SLU-10482
CAS:<p>SLU-10482, an antiparasitic agent, effectively reduces C.</p>Fórmula:C18H16F4N6OCor e Forma:SolidPeso molecular:408.35AS-2077715
CAS:<p>AS-2077715, an antifungal agent, exhibits inhibitory activity against Trichophyton species and is derived from the fermentation broth of Capnodium sp. 339855. It is utilized in the study of fungal infections [1].</p>Fórmula:C25H41NO7Cor e Forma:SolidPeso molecular:467.6Tuberculosis inhibitor 7
CAS:<p>Tuberculosis inhibitor 7 (compound 2d), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, exhibits potent activity against Mycobacterium tuberculosis and</p>Fórmula:C21H18FN3O2SCor e Forma:SolidPeso molecular:395.45ZINC475239213
CAS:<p>ZINC475239213 acts as an inhibitor targeting the SARS-CoV-2 Nsp14 N7-Methyltransferase with an IC50 value of 20 μM [1].</p>Fórmula:C21H15N5O2Pureza:98%Cor e Forma:SolidPeso molecular:369.38YH-53
CAS:<p>YH-53: potent inhibitor for SARS-CoV-1 (Ki=6.3 nM) & SARS-CoV-2 3CLpro (Ki=34.7 nM); hinders SARS-CoV-2 replication; aids COVID-19 research.</p>Fórmula:C30H33N5O5SCor e Forma:SolidPeso molecular:575.68NNRTIs-IN-1
CAS:<p>NNRTIs-IN-1 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with notable anti-resistance efficacy, effectively inhibiting both the wild-type</p>Fórmula:C28H22N6O3Cor e Forma:SolidPeso molecular:490.51Ibuzatrelvir
CAS:<p>Ibuzatrelvir (PF-07817883) is an antiviral compound designed to inhibit the SARS-CoV-2 3CL protease, and is utilized in the treatment of COVID-19 [1].</p>Fórmula:C21H30F3N5O5Pureza:98%Cor e Forma:SolidPeso molecular:489.49MoTPS1-IN-1
CAS:<p>MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal anti-inflammatory activity that acts through interaction with Glu396 study ulcerative colitis.</p>Fórmula:C23H27F3N2O4Pureza:99.28%Cor e Forma:SoildPeso molecular:452.47Influenza virus-IN-6
CAS:<p>Influenza virus-IN-6 (Compound 35) serves as a potent inhibitor targeting the N-terminal domain of the polymerase acidic protein (PA N ) endonuclease subunit of</p>Fórmula:C27H26ClNO7Pureza:98%Cor e Forma:SolidPeso molecular:511.95Avarofloxacin
CAS:<p>Avarofloxacin (JNJ-Q2) is a fluoroquinolone for treating bacterial skin infections and pneumonia.</p>Fórmula:C21H23F2N3O4Cor e Forma:SolidPeso molecular:419.42Disoxaril
CAS:<p>Disoxaril (BRN 3626820, WIN 51711), an anti-picornavirus, blocks enterovirus by targeting VP1; boosts poliovirus inhibition with Ambioxime, Bioxazole.</p>Fórmula:C20H26N2O3Cor e Forma:SolidPeso molecular:342.43Galidesivir hydrochloride
CAS:<p>Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp.</p>Fórmula:C11H16ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:301.73GSK-2485852
CAS:<p>GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.</p>Fórmula:C27H25BF2N2O6SCor e Forma:SolidPeso molecular:554.37I-A09
CAS:<p>I-A09 is a noncompetitive mPTPB inhibitor.</p>Fórmula:C29H25N5O6Pureza:98%Cor e Forma:SolidPeso molecular:539.54ALS-8112
CAS:<p>ALS-8112 is a inhibitor of respiratory syncytial virus (RSV) polymerase. The 5'-triphosphate form of ALS-8112 inhibits RSV polymerase (IC50: 0.02 μM).</p>Fórmula:C10H13ClFN3O4Pureza:98.90%Cor e Forma:SolidPeso molecular:293.68Antituberculosis agent-1
CAS:<p>Antituberculosis Agent-1 (Compound 8a) is an effective antituberculosis agent, demonstrating a minimum inhibitory concentration (MIC) of 3.84 μg/mL against</p>Fórmula:C21H21NO4Cor e Forma:SolidPeso molecular:351.4MK-3281
CAS:<p>MK-3281: Oral, potent HCV NS5B inhibitor with promising properties and efficacy in replication trials, suitable for clinical use.</p>Fórmula:C29H37N3O3Cor e Forma:SolidPeso molecular:475.62RSV L-protein-IN-5
CAS:<p>RSV L-protein-IN-5 (Compound E) serves as a potent inhibitor of the Respiratory Syncytial Virus (RSV), with an EC50 value of 0.1 μM.</p>Fórmula:C31H36N6O4Pureza:98%Cor e Forma:SolidPeso molecular:556.66Tuberculosis inhibitor 8
CAS:<p>Tuberculosis inhibitor 8 (compound 3b), a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative, exhibits potent activity against both Mycobacterium</p>Fórmula:C21H19FN4OCor e Forma:SolidPeso molecular:362.4GlcNAcstatin
CAS:<p>GlcNAcstatin, a selective glucoimidazole-based inhibitor of bacterial O-GlcNAcase, exhibits a K_i value of 4.6 pM and demonstrates a specificity that is 100,000</p>Fórmula:C20H27N3O4Cor e Forma:SolidPeso molecular:373.454'-Acetyl-chrysomycin B
CAS:<p>4'-Acetyl-chrysomycin B, a 4'-acetylated analog of chrysomycin B, exhibits anti-Gram-positive bacterial and antimicrobial activities [1].</p>Fórmula:C29H30O10Cor e Forma:SolidPeso molecular:538.54Bavtavirine
CAS:<p>Bavtavirine is a non-nucleoside reverse HIV-1 transcriptase inhibitor (NNRTIs),inhibits HIV replication by preventing the transcription of viral RNA into DNA.</p>Fórmula:C26H20N6Pureza:97.2%Cor e Forma:SolidPeso molecular:416.48Methyl 3,4-dimethoxycinnamate
CAS:<p>Methyl 3,4-dimethoxycinnamate impedes uredospore germination and concurrently inhibits global DNA methylation in Hep3B cells [1] [2].</p>Fórmula:C12H14O4Cor e Forma:SolidPeso molecular:222.24Oxynitidine
CAS:<p>Oxynitidine, an HBV inhibitor (ID50 = 30.8 µg/mL), effectively suppresses HBV DNA replication and may be utilized in viral infection research [1].</p>Fórmula:C21H17NO5Pureza:98%Cor e Forma:SolidPeso molecular:363.36Roseoflavin
CAS:<p>Roseoflavin, a chemical analog of FMN and riboflavin that has antimicrobial activity, can directly bind to FMN riboswitch aptamers and downregulate the</p>Fórmula:C18H23N5O6Pureza:99.81% - 99.89%Cor e Forma:SolidPeso molecular:405.41Antibacterial agent 135
CAS:<p>Antibacterial Agent 135 (example 7) effectively inhibits various bacteria, including P.</p>Fórmula:C11H15N5O6SCor e Forma:SolidPeso molecular:345.33Valnemulin
CAS:<p>Valnemulin, a broad-spectrum pleuromutilin antibiotic, targets peptidyl transferase within the 50S ribosomal subunit, effectively used in veterinary medicine to address swine diseases such as B. hyodysenteriae and M. hyopneumoniae.</p>Fórmula:C31H52N2O5SCor e Forma:SolidPeso molecular:564.835-DACTHF
CAS:<p>5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.</p>Fórmula:C19H24N6O6Pureza:98%Cor e Forma:SolidPeso molecular:432.43NK007
CAS:<p>NK007 is a novel anti-SARS-CoV-2 agent with an EC 50 value of 30 nM.</p>Fórmula:C28H33NO9Cor e Forma:SolidPeso molecular:527.56(1R,4S)-Yimitasvir diphosphate
CAS:<p>Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A).</p>Fórmula:C49H64N8O14P2Cor e Forma:SolidPeso molecular:1051.03Teropavimab
CAS:<p>Teropavimab (3BNC117-LS), an antibody, is utilized in the research of HIV infection [1].</p>Cor e Forma:LiquidProchloraz manganese
CAS:<p>Prochloraz manganese, an antifungal agent utilized in the agricultural sectors [1], serves to protect crops by inhibiting fungal growth.</p>Fórmula:C60H64Cl14MnN12O8Cor e Forma:SolidPeso molecular:1632.51Zika virus-IN-1
CAS:<p>Zika virus-IN-1 is an inhibitor of Zika virus (EC50: 1.56 μM).</p>Fórmula:C30H37N3O3SiCor e Forma:SolidPeso molecular:515.72Cladosporin
CAS:<p>Cladosporin, from Cladosporium cladosporioid fungus, halts dermatophyte growth on agar at 75 μg/mL.</p>Fórmula:C16H20O5Cor e Forma:SolidPeso molecular:292.33Japonilure
CAS:<p>Japonilure is an agent of insecticide and pheromone.</p>Fórmula:C14H24O2Pureza:98%Cor e Forma:SolidPeso molecular:224.34Antiviral agent 35
CAS:<p>Antiviral agent 35 (compound 4d) serves as a potent orally active inhibitor of the influenza virus, targeting early stages of viral replication.</p>Fórmula:C23H18N2O4SPureza:98%Cor e Forma:SolidPeso molecular:418.47Oxamniquine
CAS:<p>Oxamniquine is an effective compound for the treatment of schistosomiasis.</p>Fórmula:C14H21N3O3Pureza:98%Cor e Forma:Pale Yellow Crystals From Isopropanol SolidPeso molecular:279.33BVDU 5′-Triphosphate
CAS:<p>BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.</p>Fórmula:C11H16BrN2O14P3Pureza:98%Cor e Forma:SolidPeso molecular:573.08Antibacterial compound 1
CAS:<p>Antibacterial compound 1 is an antibacterial compound.</p>Fórmula:C14H16FN3O4Pureza:98%Cor e Forma:SolidPeso molecular:309.29AZD-7295
CAS:<p>AZD-7295 (A-689) is an NS5A inhibitor that may be used to treat HCV infection.</p>Fórmula:C32H35F3N4O5SCor e Forma:SolidPeso molecular:644.7Ulonivirine
CAS:<p>Ulonivirine is an orally active non-nucleoside reverse transcriptase inhibitor that exhibits high antiviral activity and can be used to study HIV-1 infection.</p>Fórmula:C18H8ClF6N5O3Cor e Forma:SolidPeso molecular:491.73Arbemnifosbuvir
CAS:<p>Arbemnifosbuvir, a drug interfering with the nidovirus DdRp-associated nucleotidyltransferase (NiRAN) domain of non-structural protein 12 (nsp12), is utilized</p>Fórmula:C24H33FN7O7PPureza:98%Cor e Forma:SolidPeso molecular:581.53Antibacterial agent 158
CAS:<p>Compound 158 (6c), a Micrococcin analogue, serves as an antibacterial agent effective against impetigo and Clostridium difficile infection (CDI) [1].</p>Fórmula:C54H61N15O8S6Cor e Forma:SolidPeso molecular:1240.55Mpro 61
CAS:<p>Mpro 61 is a potent non-covalent inhibitor of SARS-CoV-2 main protease.</p>Fórmula:C28H19Cl2FN4O4Cor e Forma:SolidPeso molecular:565.38SARS-CoV-2 3CLpro-IN-2
CAS:<p>SARS-CoV-2 3CLpro-IN-2 is a potent inhibitor of the 3CL protease pair and has shown research potential for SARS-CoV-2 disease.</p>Fórmula:C21H18F5N5O4Cor e Forma:SolidPeso molecular:499.39Murabutide
CAS:<p>Murabutide, a safe synthetic immunomodulator, diminishes the expression of CD4 and CCR5 receptors and promotes the secretion of high levels of beta-chemokines,</p>Fórmula:C23H40N4O11Cor e Forma:SolidPeso molecular:548.58Hinokinin
CAS:<p>Hinokinin (Cubebinolide), a bioactive lignan, exhibits a broad spectrum of pharmacological activities.</p>Fórmula:C20H18O6Cor e Forma:SolidPeso molecular:354.35SARS-CoV-2-IN-1
CAS:<p>SARS-CoV-2-IN-1 is a potent inhibitor of Mpro(SARS-CoV-2 Mpro, SARS-CoV Mpro and MERS-CoV Mpro with IC50s of 0.67, 0.90 and 0.58 μM, respectively).</p>Fórmula:C31H39N5O7Pureza:98%Cor e Forma:SolidPeso molecular:593.67L 680833
CAS:<p>L 680833 is an orally active monocyclic beta-lactam human polymorphonuclear leukocyte elastase inhibitor.</p>Fórmula:C27H34N2O5Cor e Forma:SolidPeso molecular:466.57Bio-AMS
CAS:<p>Bio-AMS is a potent inhibitor of bacterial biotin protein ligase, exhibiting selective activity against Mycobacterium tuberculosis (Mtb) and disrupting fatty</p>Fórmula:C20H29N9O7S2Cor e Forma:SolidPeso molecular:571.63BILR-355
CAS:<p>BILR-355 is a reverse transcriptase inhibitor.</p>Fórmula:C25H23N5O3Pureza:98%Cor e Forma:SolidPeso molecular:441.48T145
CAS:<p>T145 halts key bacteria growth at sub μg/ml, deters resistance, and may enhance drug lifespan.</p>Fórmula:C18H16N2O5Pureza:98%Cor e Forma:SolidPeso molecular:340.33Annamycin
CAS:<p>Annamycin, a semi-synthetic doxorubicin derivative, binds DNA, blocks topoisomerase II, and evades MDR, inhibiting DNA/RNA/protein synthesis.</p>Fórmula:C26H25IO11Cor e Forma:SolidPeso molecular:640.37Aranciamycin
CAS:<p>Aranciamycin (Compound 1), an anthracycline antibiotic, exhibits collagenase inhibitory activity (IC50 3.7*10^-7 M) and can inhibit DNA synthesis in tumor cells</p>Fórmula:C27H28O12Cor e Forma:SolidPeso molecular:544.5Tirfipiravir
CAS:<p>Tirapiravir is an antiviral nucleoside analog that exhibits activity against both the novel coronavirus and influenza virus [1].</p>Fórmula:C14H17N3O8Pureza:98%Cor e Forma:SolidPeso molecular:355.3FIKK9.1-IN-1
CAS:<p>FIKK9.1-IN-1 (Compound 1), an antimalarial agent (IC50: 2.68 μg/mL), serves as a FIKK9.1 inhibitor by interacting with the ATP-binding residues within FIKK9.1,</p>Fórmula:C22H22N2SePureza:98%Cor e Forma:SolidPeso molecular:393.38RyRs activator 2
CAS:<p>RyRs activator 2: potent ranibulin receptor stimulant, 30% larvicidal activity, equals chlorfenvinphos, outperforms cyanobenzamide.</p>Fórmula:C23H18Cl2F3N5O2Cor e Forma:SolidPeso molecular:524.32DHFR-IN-10
CAS:<p>DHFR-IN-10 (compound 4c) is a potent inhibitor of dihydrofolate reductase (DHFR), displaying an inhibition concentration half-maximum (IC50) of 4.21 μM against</p>Fórmula:C20H14BrN3S3Cor e Forma:SolidPeso molecular:472.44WQ 2743
CAS:<p>WQ 2743 is a potent agent of antimicrobial.</p>Fórmula:C19H15BrF3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:498.25Fosalvudine tidoxil
CAS:<p>Fosalvudine tidoxil, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C35H64FN2O8PSPureza:98%Cor e Forma:SolidPeso molecular:722.93Propiolactone
CAS:<p>Propiolactone (β-propiolactone; 2-Oxetanone), a chemosterilant, effectively inactivates viruses, rendering them non-infectious.</p>Fórmula:C3H4O2Pureza:98%Cor e Forma:SolidPeso molecular:72.06SA09-Cu
CAS:<p>SA09-Cu is a potent, noncompetitive inhibitor of NDM-1, with an IC50 of 9.6 nM.</p>Fórmula:C8H16CuN2O2S4Cor e Forma:SolidPeso molecular:364.03A 74704
CAS:<p>A 74704 is a pseudo C2-symmetric inhibitor of HIV-1 protease and its diester analog.</p>Fórmula:C43H52N4O7Pureza:98%Cor e Forma:SolidPeso molecular:736.9Myrrhterpenoid O
CAS:<p>Unfortunately, you did not provide the description of the chemical compound that needs to be rewritten.</p>Fórmula:C16H20O3Pureza:98%Cor e Forma:SolidPeso molecular:260.3312R-LOX-IN-1
CAS:<p>12R-LOX-IN-1 (Compound 4a), with an IC50 of 28.25 µM, is an inhibitor of 12R-LOX.</p>Fórmula:C15H11NO2Cor e Forma:SolidPeso molecular:237.25NSC 288387
CAS:<p>NSC 288387, a pan-flavivirus MTase inhibitor, binds to the SAM-binding pocket and effectively inhibits Zika virus (ZIKV) with an IC50 of 0.2 μM, also preventing</p>Fórmula:C19H16N4O3Pureza:98%Cor e Forma:SolidPeso molecular:348.36DAM-IN-1
CAS:<p>DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.</p>Fórmula:C16H17NO4Pureza:98%Cor e Forma:SolidPeso molecular:287.31Vaborbactam
CAS:<p>Vaborbactam (RPX7009) is a β-lactamase inhibitor that is often used in conjunction with meropenem to study pneumonia and CRE infections.</p>Fórmula:C12H16BNO5SPureza:97.29%Cor e Forma:SolidPeso molecular:297.14SDH-IN-3
CAS:<p>SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor, demonstrating potent antifungal activity with an inhibition concentration (IC50) of 7.2 μg/mL and an</p>Fórmula:C15H11F2N3OSPureza:98%Cor e Forma:SolidPeso molecular:319.33hDHODH-IN-1
CAS:<p>hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.</p>Fórmula:C17H14N2O2Pureza:99.97%Cor e Forma:SolidPeso molecular:278.31XSJ2-46
CAS:<p>XSJ2-46, a 5'-amino NI analog, is an antiviral agent possessing anti-Zika virus properties and demonstrates reasonable inhibition of RNA-dependent RNA</p>Fórmula:C25H24ClF3N6O3Pureza:98%Cor e Forma:SolidPeso molecular:548.95SPR38
<p>SPR38: SARS-CoV-2 protease inhibitor with Ki 0.260 μM; also blocks hCatL (Ki 1.92 μM) and hCatB (Ki 11.1 μM).</p>Fórmula:C24H33N3O5Cor e Forma:SolidPeso molecular:443.54Antimalarial agent 10
CAS:<p>Compound 17b, an amino alcohol-quinoline, targets Pf3D7 (IC50: 14.9 nM) and PfW2 (IC50: 11 nM) with selectivity index >770.</p>Fórmula:C23H22F6N2O2Cor e Forma:SolidPeso molecular:472.42RSV L-protein-IN-3
CAS:<p>RSV L-protein-IN-3 is an inhibitor of the wild-type RSV polymerase, exhibiting an IC50 of 10.4 μM and an EC50 of 2.1 μM (against RSV), and possesses lower</p>Fórmula:C31H34N4O4Pureza:98%Cor e Forma:SolidPeso molecular:526.63MC-VC-PAB-Cyclohexanediamine-Thailanstatin A
CAS:<p>MC-VC-PAB-Cyclohexanediamine-Thailanstatin A is a spliceostatin analog and a drug-linker conjugate for antibody-drug conjugates (ADC), comprising the cytotoxic</p>Fórmula:C63H91N9O16Pureza:98%Cor e Forma:SolidPeso molecular:1230.45RSV L-protein-IN-2
CAS:<p>RSV L-protein-IN-2 (Compound A), a noncompetitive inhibitor of the RSV polymerase (IC50: 4.5 μM), exhibits antiviral activity against long RSV strains (EC50: 1.</p>Fórmula:C32H36N4O5Pureza:98%Cor e Forma:SolidPeso molecular:556.65Antituberculosis agent-6
CAS:<p>Antituberculosis agent-6: potent against M. tuberculosis (MIC 3.49 μM), antifungal (MIC 62.5 μM), high GI absorption.</p>Fórmula:C27H20F2N2O3Cor e Forma:SolidPeso molecular:458.46Targeting the bacterial sliding clamp peptide 46
CAS:<p>Peptide 46 is a short peptide that inhibits SC-dependent DNA synthesis by targeting the bacterial sliding clamp (SC).</p>Fórmula:C47H64N8O11Cor e Forma:SolidPeso molecular:917.06Lagociclovir valactate
CAS:<p>Lagociclovir valactate is a prodrug of Lagociclovir . Lagociclovir valactate is an orally active anti- HBV agent [1] .</p>Fórmula:C18H25FN6O6Cor e Forma:SolidPeso molecular:440.43Votoplam
CAS:<p>Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].</p>Fórmula:C21H25N9OPureza:98%Cor e Forma:SolidPeso molecular:419.48NSC309401 dihydrochloride
CAS:<p>NSC309401 is an E. coli dihydrofolate reductase inhibitor with an IC50 value of 189 nM and a dissociation constant (Kd) of 14.57 nM [1].</p>Fórmula:C17H18Cl2N6Cor e Forma:SolidPeso molecular:377.27EHNA hydrochloride
CAS:<p>EHNA hydrochloride is a PDE2 and ADA inhibitor with anticancer activity, increasing intracellular adenosine concentration in a treatment time-dependent manner.</p>Fórmula:C14H24ClN5OPureza:98%Cor e Forma:SolidPeso molecular:313.83HCV-IN-44
CAS:<p>HCV-IN-44 (compound 28) is an inhibitor of the HCV NS5B protein, efficacious in suppressing HCV virus replication and useful for researching HCV infection [1].</p>Fórmula:C24H26FN3O5SCor e Forma:SolidPeso molecular:487.54SARS-CoV-2/MERS Mpro-IN-1
<p>SARS-CoV-2/MERS Mpro-IN-1 is a potent inhibitor of the main proteases in SARS-CoV-2 and MERS, exhibiting IC50 values of 0.10 and 0.06 µM, respectively.</p>Fórmula:C30H36N4O7Cor e Forma:SolidPeso molecular:564.63Quorum Sensing-IN-2
CAS:<p>Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor that curtails bacterial pathogenicity without impeding growth.</p>Fórmula:C19H13F2NO3Cor e Forma:SolidPeso molecular:341.31WRN inhibitor 1
CAS:<p>WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.</p>Fórmula:C16H13FN2O4SPureza:98%Cor e Forma:SolidPeso molecular:348.35NCI-B16
CAS:<p>NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].</p>Fórmula:C27H26N8O4Cor e Forma:SolidPeso molecular:526.55RNA polymerase II-IN-1
CAS:<p>RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.</p>Fórmula:C38H53N11O12SPureza:98%Cor e Forma:SolidPeso molecular:887.964-Hydroxy-2-methylbenzenesulfonic acid ammonium
CAS:<p>4-Hydroxy-2-methylbenzene ammonium: Policresulen impurity, inhibits NS2B/NS3 protease (IC50: 0.48 μg/mL), hinders DENV2 in BHK-21 cells (IC50: 4.99 μg/mL).</p>Fórmula:C7H11NO4SPureza:98%Cor e Forma:SolidPeso molecular:205.23IpOHA
CAS:<p>IpOHA is a potent inhibitor of plant KARI and functions as an antimycobacterial agent, demonstrating a K_i value of 97.7 nM against Mycobacterium tuberculosis (</p>Fórmula:C5H9NO4Cor e Forma:SolidPeso molecular:147.13NS5A-IN-3
CAS:<p>NS5A-IN-3 is a potent NS5A inhibitor with high efficacy against HCV 1b, good activity on 3a, and strong metabolic stability; superior to daclatasvir.</p>Fórmula:C44H44N6O8Pureza:98%Cor e Forma:SolidPeso molecular:784.86DDD85646
CAS:<p>DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.</p>Fórmula:C21H24Cl2N6O2SPureza:97.8% - 99.76%Cor e Forma:SolidPeso molecular:495.43BLI-489 Hydrate
CAS:<p>BLI-489 hydrate is a penicillin β-lactamase inhibitor that acts on classes A and C and some class D β-lactamases.</p>Fórmula:C13H10N3NaO4SCor e Forma:SolidPeso molecular:327.29Mansonone F
CAS:<p>Mansonone F is a topoisomerase II inhibitor with cytotoxic and topo inhibitory potencies.</p>Fórmula:C15H12O3Cor e Forma:SolidPeso molecular:240.25Dihydroaltenuene B
CAS:<p>Dihydroaltenuene B inhibits mushroom tyrosinase (IC50: 38.33µM) and binds His244, Met280, Gly281 via hydrogen bonds.</p>Fórmula:C15H18O6Cor e Forma:SolidPeso molecular:294.3UCB7362
CAS:<p>UCB7362 (GLXC-26743) is an orally available and potent plasmepsin X (PMX) inhibitor with anti-malarial activity.UCB7362 inhibits parasite reproduction.</p>Fórmula:C25H26ClN5O3Pureza:97.67%Cor e Forma:SolidPeso molecular:479.96Antileishmanial agent-17
CAS:<p>Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells.</p>Fórmula:C27H37N5O5Pureza:98%Cor e Forma:SolidPeso molecular:511.61G4/HDAC-IN-1
<p>G4/HDAC-IN-1, a G4/HDAC dual inhibitor, IC50 1.1 µM, blocks TNBC growth, useful in cancer research.</p>Fórmula:C36H49ClFN7O4Cor e Forma:SolidPeso molecular:698.27MsbA-IN-6
CAS:<p>MsbA-IN-6: potent antibiotic, hinders MsbA in gram-negative bacteria, kills E. coli, effective on drug-resistant strains.</p>Fórmula:C24H20Cl2N4OPureza:98%Cor e Forma:SolidPeso molecular:451.35HOE961
CAS:<p>HOE961, a diacetate ester prodrug of S2242, is an oral anti-orthopoxvirus agent effective against cowpox.</p>Fórmula:C13H17N5O5Cor e Forma:SolidPeso molecular:323.3RAD51-IN-4
CAS:<p>RAD51-IN-4, a potent RAD51 inhibitor, may be useful in researching mitochondrial defect-related conditions.</p>Fórmula:C31H34FN5O5S2Cor e Forma:SolidPeso molecular:639.765,6,7,8-Tetrahydro-8-deazahomofolic acid
CAS:<p>5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.</p>Fórmula:C21H26N6O6Cor e Forma:SolidPeso molecular:458.47Flurofamide
CAS:<p>Flurofamide is an effective bacterial urease inhibitor and has potential in the treatment of infected urinary calculi.</p>Fórmula:C7H9FN3O2PPureza:96.01% - 98%Cor e Forma:SolidPeso molecular:217.14GSK3532795
CAS:<p>GSK3532795: potent oral HIV-1 maturation inhibitor; EC50: 1.9-13 nM for various strains.</p>Fórmula:C42H62N2O4SPureza:98%Cor e Forma:SolidPeso molecular:691.021,8-Dichloroanthraquinone
CAS:<p>1,8-Dichloroanthraquinone, a derivative of anthraquinone, effectively inhibits sulfide production in sulfate-reducing bacteria [1].</p>Fórmula:C14H6Cl2O2Cor e Forma:SolidPeso molecular:277.1Antiviral agent 43
CAS:<p>Antiviral agent 43 (compound 16) serves as a potent, orally active inhibitor of influenza A virus entry, demonstrating efficacy by inhibiting the replication of the influenza A strains VH04-H5N1 and PR8-H1N1 with EC50 values of 240 nM and 72 nM, respectively [1].</p>Fórmula:C17H22ClF3N2OCor e Forma:SolidPeso molecular:362.82HIV-1 inhibitor-10
CAS:<p>HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor.</p>Fórmula:C39H54O6Cor e Forma:SolidPeso molecular:618.84Antibacterial agent 154
CAS:<p>Antibacterial Agent 154 (Compound 7), a Fluoroquinolone derivative, exhibits broad-spectrum efficacy against both Gram-positive and Gram-negative bacteria when</p>Fórmula:C25H28ClFN4O5Cor e Forma:SolidPeso molecular:518.97BMY-43748
CAS:<p>BMY-43748 is an antibacterial compound with great in vitro and in vivo antibacterial activity.</p>Fórmula:C20H17F3N4O3Pureza:98%Cor e Forma:SolidPeso molecular:418.37Azaconazole
CAS:<p>Azaconazole, an agricultural fungicide, is used for controlling powdery mildew on crops and bean rust.</p>Fórmula:C12H11Cl2N3O2Cor e Forma:SolidPeso molecular:300.14TAS-114
CAS:<p>TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.</p>Fórmula:C21H29N3O6SPureza:99.76%Cor e Forma:SolidPeso molecular:451.54L-696229
CAS:<p>L-696229: specific HIV-1 RT inhibitor, blocks viral spread in various cells.</p>Fórmula:C17H18N2O2Pureza:98%Cor e Forma:SolidPeso molecular:282.34BDM91270
CAS:<p>BDM91270 (compound 29) serves as an inhibitor of the E.</p>Fórmula:C17H21Cl3N4O2Cor e Forma:SolidPeso molecular:419.73AU1235
CAS:<p>AU1235 is a Mycobacterium tuberculosis inhibitor.</p>Fórmula:C17H19F3N2OPureza:99.54% - 99.87%Cor e Forma:SolidPeso molecular:324.347-Deaza-2',3'-dideoxyguanosine
CAS:<p>7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2′,3′-dideoxynucleoside 5′-triphosphate that inhibits HIV-1 reverse transcriptase with a Ki of 25 nM [1].</p>Fórmula:C11H14N4O3Cor e Forma:SolidPeso molecular:250.258-Azahypoxanthine
CAS:<p>8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.</p>Fórmula:C4H3N5OPureza:99.66%Cor e Forma:Light Yellow To Light Beige Fine CrystallinePeso molecular:137.1Elastase LasB-IN-1
CAS:<p>Elastase LasB-IN-1 (Compound 4b), a potent and selective inhibitor of elastase LasB, exhibits antibacterial activity and has been determined to possess an IC50</p>Fórmula:C13H17F3NO4PCor e Forma:SolidPeso molecular:339.25β-Lactamase-IN-8
CAS:<p>β-Lactamase-IN-8 (compound 20) is a potent and oral bioavailable broad-spectrum cyclic boronate β-lactamase inhibitor that can be used for researching</p>Fórmula:C10H14BNO4SCor e Forma:SolidPeso molecular:255.1MF 5137
CAS:<p>MF 5137 is an effective antimicrobial agent.</p>Fórmula:C23H23N3O3Pureza:98%Cor e Forma:SolidPeso molecular:389.45Mirincamycin HCl
CAS:<p>Mirincamycin HCl is a close analog of the drug clindamycin used for the treatment of Plasmodium falciparum blood stages.</p>Fórmula:C19H36Cl2N2O5SPureza:98%Cor e Forma:SolidPeso molecular:475.47Methyl 2-amino-5-bromobenzoate
CAS:<p>Methyl 2-amino-5-bromobenzoate (Methyl 5-Bromoanthranilate) is an HCV NS5b RNA polymerase inhibitor with antimicrobial activity.</p>Fórmula:C8H8BrNO2Pureza:98.05%Cor e Forma:SolidPeso molecular:230.06Δ2-trans Eicosenoic Acid
CAS:<p>Δ2-transEicosenoic acid, an α,β-unsaturated fatty acid, emerges as a by-product during the synthesis of Δ2-ciseicosenoic acid, which along with its salts, shows promise in diabetes treatment and lipid metabolism enhancement. Additionally, the compound 2-octadecenoic acid is recognized for its ability to enhance liver function and reduce blood sugar levels in streptozocin-induced diabetic rats.</p>Fórmula:C20H38O2Cor e Forma:SolidPeso molecular:310.5TH-Z145
CAS:<p>TH-Z145 is a potent FPPS inhibitor for the study of myeloma and lung cancer.</p>Fórmula:C16H28O7P2Pureza:98.29%Cor e Forma:SolidPeso molecular:394.34ELQ-596
CAS:<p>ELQ-596, a quinolone derivative, exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-596 attenuates babesiosis in immunosuppressed mice [1].</p>Fórmula:C24H17ClF3NO3Cor e Forma:SolidPeso molecular:459.84(S)-Mosnodenvir
CAS:<p>(S)-Mosnodenvir, a pan-serotype dengue antiviral agent, exhibits picomolar to low nanomolar in vitro activity with a high barrier to resistance and is</p>Fórmula:C26H22ClF3N2O6SPureza:98%Cor e Forma:SolidPeso molecular:582.98SARS-CoV-2-IN-63
CAS:<p>SARS-CoV-2-IN-63 (Compound R3e) serves as an inhibitor of SARS-CoV-2 replication, demonstrating low cytotoxicity.</p>Fórmula:C20H21N3O3SePureza:98%Cor e Forma:SolidPeso molecular:430.36CDD-1733
CAS:<p>CDD-1733 is a potent, non-covalent, and non-peptide inhibitor of the SARS-CoV-2 main protease (Mpro) with an inhibition constant (K i) of 12 nM.</p>Fórmula:C34H32F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:599.65WRN inhibitor 2
CAS:<p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>Fórmula:C15H11F3N2O5S2Pureza:98%Cor e Forma:SolidPeso molecular:420.38Antifungal agent 49
CAS:<p>Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].</p>Fórmula:C15H12O4Cor e Forma:SolidPeso molecular:256.25Laxifloran
CAS:<p>Laxifloran possesses antibacterial and antifungal properties.</p>Fórmula:C17H18O5Cor e Forma:SolidPeso molecular:302.32Dehydroemetine
CAS:<p>Dehydroemetine, a synthetic emetine, treats amoebic infections and leishmaniasis, and resists metronidazole amoebiosis.</p>Fórmula:C29H38N2O4Pureza:98.68% - 99.68%Cor e Forma:SolidPeso molecular:478.62DHX9-IN-2
CAS:<p>DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.</p>Fórmula:C18H16ClN3O3S2Pureza:98%Cor e Forma:SolidPeso molecular:421.92MMV688533
CAS:<p>MMV688533 has antimalarial activity.</p>Fórmula:C24H15F6N5O2Pureza:99.12%Cor e Forma:SoildPeso molecular:519.4GSK3186899
CAS:<p>GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.</p>Fórmula:C19H28F3N7O3SPureza:98.35% - 99.61%Cor e Forma:SolidPeso molecular:491.53Nesbuvir
CAS:<p>Nesbuvir: HCV NS5B polymerase inhibitor, IC50 9 nM against HCV 1b replicon in liver cancer cells.</p>Fórmula:C22H23FN2O5SPureza:99.99%Cor e Forma:SolidPeso molecular:446.49Ziresovir
CAS:<p>Ziresovir (RO-0529) is a respiratory syncytial virus fusion protein (RSV F) inhibitor that inhibits RSV and can be used to study syncytial virus sense.</p>Fórmula:C22H25N5O3SPureza:95.51% - >99.99%Cor e Forma:SolidPeso molecular:439.53Thymectacin
CAS:<p>Thymectacin (NB 1011) is a selective thymidine synthase (TS) inhibitor with anticancer activity for the study of colon cancer and solid tumors.</p>Fórmula:C21H25BrN3O9PPureza:97.05% - 99.49%Cor e Forma:SolidPeso molecular:574.32Valomaciclovir stearate
CAS:<p>S-Allylmercapturic Acid (N-Acetyl-S-allyl-L-cysteine) is a metabolite of S-allyl-L-cysteine present in black garlic, with potential anti-gout effects.</p>Fórmula:C33H58N6O5Pureza:99.18% - >99.99%Cor e Forma:SolidPeso molecular:618.852,4′-Dichloroacetanilide
CAS:<p>2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.</p>Fórmula:C8H7Cl2NOPureza:99.36%Cor e Forma:SolidPeso molecular:204.05A7132
CAS:<p>A7132 is an antibacterial agent and possesses broad and potent antibacterial activity.</p>Fórmula:C19H16F2N4O3Pureza:95.49%Cor e Forma:SolidPeso molecular:386.35Linvencorvir
CAS:<p>Linvencorvir is a hepatitis B virus (HBV) core protein variant modifier used to treat chronic HBV infection.</p>Fórmula:C29H35FN6O5SPureza:99.9% - 99.9%Cor e Forma:SolidPeso molecular:598.69Tenofovir amibufenamide
CAS:<p>Tenofovir amibufenamide (HS-10234) 是一种 Tenofovir 前药，是一种具有口服活性的抗病毒化合物。Tenofovir amibufenamide 对乙型肝炎病毒 (HBV)具有抑制作用，可用于慢性乙型肝炎 (CHB) 研究。</p>Fórmula:C22H31N6O5PPureza:99.19% - 99.87%Cor e Forma:SolidPeso molecular:490.49Contezolid
CAS:<p>Contezolid (MRX-I) is an antibiotic with bactericidal activity and can be used to study tuberculosis.</p>Fórmula:C18H15F3N4O4Pureza:99.41%Cor e Forma:SolidPeso molecular:408.33CWHM-1552
CAS:<p>CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.</p>Fórmula:C22H27F2N3OPureza:99.56%Cor e Forma:SolidPeso molecular:387.47ZY-19489
CAS:<p>ZY-19489: Antimalarial, potential single-dose cure, FDA orphan drug status.</p>Fórmula:C24H32FN9Pureza:>99.99%Cor e Forma:SoildPeso molecular:465.57LNA-Adenosine
CAS:<p>LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.</p>Fórmula:C11H13N5O4Pureza:99.15%Cor e Forma:SolidPeso molecular:279.25SMN-C3
CAS:<p>SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).</p>Fórmula:C24H28N6OPureza:99.01% - 99.05%Cor e Forma:SolidPeso molecular:416.52Salicyl-AMS
CAS:<p>Salicyl-AMS is an inhibitor of mycobacterium auxin biosynthesis that inhibits the growth of mycobacterium in the presence of iron deficiency in vitro.</p>Fórmula:C17H18N6O8SPureza:98.19%Cor e Forma:SolidPeso molecular:466.43Filibuvir
CAS:<p>Filibuvir (PF-00868554) inhibits HCV polymerase genotypes 1a/1b, EC50s 59 nM.</p>Fórmula:C29H37N5O3Pureza:99.28% - >99.99%Cor e Forma:SolidPeso molecular:503.64TCMDC-135051
CAS:<p>TCMDC-135051: Selective PfCLK3 inhibitor, low toxicity, halts parasite growth & transmission; EC50=320 nM.</p>Fórmula:C29H33N3O3Pureza:99.05%Cor e Forma:SolidPeso molecular:471.59Leritrelvir
CAS:<p>Dermatan sulphate sodium (Chondroitin sulfate B sodium salt) is a linear sulfated polysaccharide, a glycosaminoglycan component of important proteoglycans.</p>Fórmula:C31H44F3N5O6Pureza:97.42%Cor e Forma:SolidPeso molecular:639.71Sorivudine
CAS:<p>Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.</p>Fórmula:C11H13BrN2O6Pureza:99.74%Cor e Forma:SolidPeso molecular:349.13Lomibuvir
CAS:<p>Lomibuvir (VCH-222, VX-222) is an allosteric inhibitor of HCV NS5B with Kd 17 nM, blocks RNA elongation, EC50 5.2 nM for 1b/Con1.</p>Fórmula:C25H35NO4SPureza:99.83%Cor e Forma:SolidPeso molecular:445.61CeMMEC1
CAS:<p>CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).</p>Fórmula:C19H16N2O4Pureza:98.9% - 99.92%Cor e Forma:SolidPeso molecular:336.34Polθ-IN-6
CAS:<p>Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.</p>Fórmula:C25H23N3O3SCor e Forma:SolidPeso molecular:445.53Zorubicin
CAS:<p>Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.</p>Fórmula:C34H35N3O10Cor e Forma:SolidPeso molecular:645.66Beclabuvir
CAS:<p>Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.</p>Fórmula:C36H45N5O5SPureza:99.87% - 99.93%Cor e Forma:SolidPeso molecular:659.84Valopicitabine
CAS:<p>Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic</p>Fórmula:C15H24N4O6Pureza:98%Cor e Forma:SolidPeso molecular:356.37Enantiomer of Sofosbuvir
<p>Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.</p>Fórmula:C22H29FN3O9PPureza:98%Cor e Forma:SolidPeso molecular:529.45JPL
CAS:<p>JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].</p>Fórmula:C19H20Cl2O2Cor e Forma:SolidPeso molecular:351.27Antimicrobial agent-38
CAS:<p>Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.</p>Fórmula:C14H11N3O4SCor e Forma:SolidPeso molecular:317.32NDM-1 inhibitor-5
CAS:<p>NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].</p>Fórmula:C24H23NO4Cor e Forma:SolidPeso molecular:389.44ZK-316
CAS:<p>ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.</p>Fórmula:C27H22D6N6O3S2Cor e Forma:SolidPeso molecular:554.72MPro N3
CAS:<p>Mpro inhibitor blocks MHV-A29, HCoV-229E, FOPV (IC50: 2.7–8.8 μM), and SARS-CoV-2 (IC50: 16.8 μM) in plaque assays.</p>Fórmula:C35H48N6O8Cor e Forma:SolidPeso molecular:680.79ABT-072
CAS:<p>ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.</p>Fórmula:C24H27N3O5SPureza:98%Cor e Forma:SolidPeso molecular:469.55AK-968-11563024
CAS:<p>AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.</p>Fórmula:C18H13I2N9O5Cor e Forma:SolidPeso molecular:689.162Piperacillin hydrate
CAS:<p>Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.</p>Fórmula:C23H29N5O8SCor e Forma:SolidPeso molecular:535.57BRD-4592
CAS:<p>BRD-4592 is an allosteric inhibitor targeting tryptophan synthase (TrpAB) of Mycobacterium tuberculosis. It binds at the α-β subunit interface of TrpAB, with an IC50 of 70.9 nM for the α subunit and 22.6 nM for the β subunit.</p>Fórmula:C17H15FN2OCor e Forma:SolidPeso molecular:282.312MDL-860
CAS:<p>MDL-860 is a broad-spectrum antiviral compound targeting small RNA viruses and exhibits low cytotoxicity to human cells. MDL-860 is useful for research into viral infections.</p>Fórmula:C13H6Cl2N2O3Cor e Forma:SolidPeso molecular:309.104DL-2-Aminopimelic Acid
CAS:<p>DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.</p>Fórmula:C7H13NO4Cor e Forma:SolidPeso molecular:175.18BPR3P0128
CAS:<p>BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].</p>Fórmula:C22H18BrN3O2Cor e Forma:SolidPeso molecular:436.30InhA-IN-7
CAS:<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Fórmula:C17H18Cl2O2Cor e Forma:SolidPeso molecular:325.23Pol I-IN-1
<p>Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition</p>Fórmula:C23H22N4O2Cor e Forma:SolidPeso molecular:386.45GRL-190-21
CAS:<p>GRL-190-21 (compound 5e), an inhibitor of SARS-Cov-2-Mpro, shows potent antiviral activity, with a K_i of 0.04 nM and an EC_50 of 0.26 μM in VeroE6 cells. It significantly reduces the infectivity, replication, and cytopathic effect of SARS-CoV-2 without notable toxicity [1].</p>Fórmula:C24H34F3N5O4Cor e Forma:SolidPeso molecular:513.55NBTIs-IN-5
CAS:<p>NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.</p>Fórmula:C24H25F3N4O2Cor e Forma:SolidPeso molecular:458.483HKT-IN-1
CAS:<p>3HKT-IN-1 (Compound 17122279) is an inhibitor of Anopheles gambiae 3-hydroxykynurenine transaminase (3HKT) and is utilized in malaria research.</p>Fórmula:C12H11BrN2O3Cor e Forma:SolidPeso molecular:311.131NITD-688
CAS:<p>NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.</p>Fórmula:C25H32N4O3S2Cor e Forma:SolidPeso molecular:500.68Quorum sensing-IN-9
CAS:<p>Quorum sensing-IN-9 (Compound 7d) inhibits quorum sensing in Pseudomonas aeruginosa by binding to the PqsR protein. It suppresses the expression of quorum sensing system-related genes lasB, rhlA, and pqsA, thereby preventing the production of virulence factors elastase, pyocyanin, and rhamnolipid. Quorum sensing-IN-9 disrupts the motility of P. aeruginosa, inhibits biofilm formation, and reduces the bacterium's virulence and pathogenicity. Additionally, it exhibits anti-infective activity in the Galleria mellonella larval model.</p>Fórmula:C9H10OS2Cor e Forma:SolidPeso molecular:198.305Pibrozelesin
CAS:<p>Pibrozelesin, a water-soluble duocarmycin B2 derivative, binds AT-rich DNA, blocking replication and inducing cell death.</p>Fórmula:C32H36BrN5O8Cor e Forma:SolidPeso molecular:698.56AB25583
CAS:<p>AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.</p>Fórmula:C22H17ClN4O3SCor e Forma:SolidPeso molecular:452.91Antibacterial agent 63
CAS:<p>Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to a</p>Fórmula:C35H43N9O14S2Cor e Forma:SolidPeso molecular:877.9Lavendomycin
CAS:<p>Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.</p>Fórmula:C29H50N10O8Cor e Forma:SolidPeso molecular:666.77G247
<p>G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.</p>Fórmula:C24H19Cl2FO3Cor e Forma:SolidPeso molecular:445.31TCMDC-136230
<p>TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.</p>Fórmula:C24H34N4O2SCor e Forma:SolidPeso molecular:442.62
