GluR
Inibidores do Receptor de Glutamato são compostos que bloqueiam a atividade dos receptores de glutamato, os principais receptores de neurotransmissores excitatórios no cérebro. Esses receptores desempenham um papel crucial na transmissão sináptica, plasticidade, aprendizado e memória. A desregulação da sinalização do glutamato está associada a vários distúrbios neurológicos, como epilepsia, AVC e doenças neurodegenerativas. Os inibidores dos receptores de glutamato são essenciais para investigar os mecanismos de excitotoxicidade e desenvolver estratégias neuroprotetoras. Na CymitQuimica, oferecemos uma gama de inibidores de receptores de glutamato para apoiar sua pesquisa em função sináptica, neuroproteção e distúrbios cognitivos.
Foram encontrados 255 produtos de "GluR"
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Basimglurant
CAS:<p>Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).</p>Fórmula:C18H13ClFN3Pureza:98.35%Cor e Forma:SolidPeso molecular:325.77Decoglurant
CAS:<p>Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.</p>Fórmula:C21H11F6N5Pureza:99.77%Cor e Forma:SolidPeso molecular:447.34VU0650786
CAS:<p>VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.</p>Fórmula:C18H15ClFN5O2Pureza:99.09%Cor e Forma:SolidPeso molecular:387.8DHPG
CAS:<p>DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.</p>Fórmula:C8H9NO4Pureza:99.55%Cor e Forma:SolidPeso molecular:183.16Org-26576
CAS:<p>Org-26576 is a positive allosteric modulator of the AMPA receptor.</p>Fórmula:C11H12N2O2Pureza:99.67%Cor e Forma:SolidPeso molecular:204.23LY339434 HCl
<p>LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)</p>Fórmula:C18H20ClNO4Pureza:97.96% - 99.68%Cor e Forma:SoildPeso molecular:349.81Piracetam
CAS:<p>Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.</p>Fórmula:C6H10N2O2Pureza:97.16%Cor e Forma:Crystals From Isopropanol SolidPeso molecular:142.16γ-DGG acetate(6729-55-1 free base)
CAS:<p>gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.</p>Fórmula:C9H16N2O7Pureza:99.81%Cor e Forma:SolidPeso molecular:264.23(R)-ADX-47273
CAS:<p>(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).</p>Fórmula:C20H17F2N3O2Pureza:99.87%Cor e Forma:SolidPeso molecular:369.36(R)-3,4-DCPG HCl
<p>(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal</p>Fórmula:C10H10ClNO6Pureza:98.80% - 99.89%Cor e Forma:SoildPeso molecular:275.64AZD-8529 mesylate
CAS:<p>AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).</p>Fórmula:C25H28F3N5O6SPureza:99.19%Cor e Forma:SolidPeso molecular:583.58KM02894
CAS:<p>KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.</p>Fórmula:C7H9N3OS2Pureza:99.98%Cor e Forma:SolidPeso molecular:215.3NBQX disodium
CAS:<p>NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.</p>Fórmula:C12H6N4Na2O6SPureza:97.6% - 98.22%Cor e Forma:SolidPeso molecular:380.2415LY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Fórmula:C25H31F2NO11SCor e Forma:SolidPeso molecular:591.58LY3027788 hydrochloride
CAS:<p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>Fórmula:C25H32ClF2NO11SCor e Forma:SolidPeso molecular:628.03LY2812223
CAS:<p>LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).</p>Fórmula:C10H12N4O4SPureza:98%Cor e Forma:SolidPeso molecular:284.29ML353
<p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>Fórmula:C19H15FN2OPureza:99.98% - 99.98%Cor e Forma:SoildPeso molecular:306.33GYKI-47261 dihydrochloride
CAS:<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Fórmula:C18H17Cl3N4Pureza:98.32% - 99.14%Cor e Forma:SolidPeso molecular:395.71mGluR5 modulator 1
CAS:<p>mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.</p>Fórmula:C18H19ClFN3O2Cor e Forma:SolidPeso molecular:363.82JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Cor e Forma:Solid
