Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 693 produtos de "Células - tronco e Derivados"

Pureza (%)

100

produtos por página.

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Tarlatamab
CAS:
- 2307488-83-9
"Tarlatamab (AMG-757), a BiTE antibody, targets DLL3, prevalent in SCLC tumors with scant normal tissue expression, and shows promise for SCLC research."
Cor e Forma:Liquid
Ref: TM-T76986
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Solrikitug
CAS:
- 2768721-24-8
Solrikitug,Anti-CRLF2 humanized IgG1κ monoclonal antibody.
Pureza:95%
Cor e Forma:Liquid
Ref: TM-T9901A-527
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Trevogrumab
CAS:
- 1429201-24-0
Trevogrumab is a human monoclonal antibody that inhibits myostatin (GDF8) to promote muscle growth, and is under research for treating age-related muscle loss (sarcopenia).
Pureza:95% - 95%
Cor e Forma:Liquid
Ref: TM-T80951
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Nisevokitug
CAS:
- 2649854-92-0
Nisevokitug (anti-TGF-β mAb) neutralizes TGF-β and is being studied for its ability to modulate the immunosuppressive tumor microenvironment.
Pureza:95%
Cor e Forma:Liquid
Ref: TM-T80562
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Tarextumab
CAS:
- 1359940-55-8
Tarextumab is an anti-Notch2/3 mAb, a promising candidate for breast, lung, ovarian, and pancreatic cancers.
Pureza:95%
Cor e Forma:Liquid
Ref: TM-T76829
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ZM39923
CAS:
- 273727-89-2
ZM39923 is a JAK3 inhibitor (pIC50: 7.1). ZM39923 also effectively inhibits tissue transglutaminase (IC50: 10 nM).
Fórmula:C₂₃H₂₅NO
Pureza:98%
Cor e Forma:Solid
Peso molecular:331.45
Ref: TM-T17295
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1-Azakenpaullone
CAS:
- 676596-65-9
1-Azakenpaullone (azakenpaullone) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.
Fórmula:C₁₅H₁₀BrN₃O
Pureza:99.73%
Cor e Forma:Tan Solid
Peso molecular:328.16
Ref: TM-T6358
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(3S,4S)-Tofacitinib
CAS:
- 1092578-47-6
(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.
Fórmula:C₁₆H₂₀N₆O
Pureza:98%
Cor e Forma:Solid
Peso molecular:312.37
Ref: TM-T13426L
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γ-secretase modulator 1
CAS:
- 1172637-87-4
gamma-secretase modulator 1 is a modulator of γ secretase and can be used in studies about the treatment of Alzheimer's disease.
Fórmula:C₂₄H₂₄N₄OS
Pureza:99.75% - 99.96%
Cor e Forma:Solid
Peso molecular:416.54
Ref: TM-T11358
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β-catenin/CBP-IN-1
CAS:
- 1198780-38-9
β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-catenin
Fórmula:C₃₃H₃₅N₆O₇P
Pureza:98%
Cor e Forma:Solid
Peso molecular:658.64
Ref: TM-T12537
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JAK3-IN-9
CAS:
- 1430095-30-9
JAK3-IN-9, potent JAK3 inhibitor, IC50 of 1.7 nM, highly selective, low toxicity, orally bioavailable, shows anti-arthritis activity.
Fórmula:C₁₇H₂₃N₅O₄S
Cor e Forma:Solid
Peso molecular:393.46
Ref: TM-T61814
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INCB16562
CAS:
- 933768-63-9
INCB16562: oral JAK1/2 inhibitor, halts IL-6/STAT3 in myeloma cells, boosts drug efficacy, stunts myeloma in mice.
Fórmula:C₁₉H₁₁Cl₂N₅
Cor e Forma:Solid
Peso molecular:380.23
Ref: TM-T68306
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1,2,3,4,5,6-Hexabromocyclohexane
CAS:
- 1837-91-8
Inhibits JAK2 autophosphorylation; non-cytotoxic at 100μM; 1μM reduces activity by 50%, 50μM nearly abolishes it.
Fórmula:C₆H₆Br₆
Pureza:98%
Cor e Forma:Solid
Peso molecular:557.54
Ref: TM-T22462
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SD-1029
CAS:
- 118372-34-2
SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling.
Fórmula:C₂₅H₃₂Br₂Cl₂N₂O₃
Cor e Forma:Solid
Peso molecular:639.25
Ref: TM-T24774
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MS-1020
CAS:
- 1255516-86-9
MS-1020 inhibits JAK3/STAT3, blocks active JAK3, suppresses JAK3/STAT5 signaling, and targets STAT3 in certain cells.
Fórmula:C₂₁H₁₈N₂O₃
Pureza:98%
Cor e Forma:Solid
Peso molecular:346.38
Ref: TM-T28113
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3F8
CAS:
- 159109-11-2
3F8 is a selective GSK-3β inhibitor that can be used as a new tool and potential therapeutic candidate compound for GSK3-related diseases, and can be used in
Fórmula:C₁₅H₁₄N₂O₄
Pureza:98.14% - 98.25%
Cor e Forma:Solid
Peso molecular:286.28
Ref: TM-T22180
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Jaspamycin
CAS:
- 22242-96-2
Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.
Fórmula:C₁₂H₁₂N₄O₅
Cor e Forma:Solid
Peso molecular:292.25
Ref: TM-T11711
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(Rac)-SIS3 free base
CAS:
- 1009104-85-1
SIS3 free base is a potent and selective Smad3 phosphorylation inhibitor. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1.
Fórmula:C₂₈H₂₇N₃O₃
Pureza:98%
Cor e Forma:Solid
Peso molecular:453.53
Ref: TM-T12923
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Tyk2-IN-7
CAS:
- 1609391-90-3
Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM).
Fórmula:C₁₈H₁₅D₃N₆O₃S
Pureza:98%
Cor e Forma:Solid
Peso molecular:401.46
Ref: TM-T13235
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JAK-IN-10
CAS:
- 916741-98-5
JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.
Fórmula:C₂₀H₁₈FN₅O₃S
Pureza:99.53%
Cor e Forma:Solid
Peso molecular:427.45
Ref: TM-T13571