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Células - tronco e Derivados

Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 695 produtos de "Células - tronco e Derivados"

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  • Stafib-2
    Targetmol
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    Stafib-2

    CAS:
    <p>Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 μM,</p>
    Fórmula:C28H26N2O12P2
    Pureza:98.48%
    Cor e Forma:Solid
    Peso molecular:644.46

    Ref: TM-T9646

  • GSM-1
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    GSM-1

    CAS:
    <p>GSM-1 is a modulator of γ-Secretase.</p>
    Fórmula:C26H31ClF3NO2
    Cor e Forma:Solid
    Peso molecular:481.98

    Ref: TM-T24116

  • ABBV-712
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    ABBV-712

    CAS:
    <p>ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 μM, and is implicated in the regulation of autoimmune diseases</p>
    Fórmula:C24H28N4O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:452.5

    Ref: TM-T83218

  • SWTX-143
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    SWTX-143

    CAS:
    <p>SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional</p>
    Fórmula:C19H18F3N3O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:361.36

    Ref: TM-T81056

  • DT-6
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    DT-6

    CAS:
    <p>DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing</p>
    Fórmula:C89H130N20O29S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2008.23

    Ref: TM-T79789

  • QL-1200186
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    QL-1200186

    CAS:
    <p>QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ (IFNγ) production following</p>
    Fórmula:C26H27N7O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:485.54

    Ref: TM-T81331

  • JAK kinase-IN-1
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    JAK kinase-IN-1

    CAS:
    <p>JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32</p>
    Fórmula:C17H19F2N7OS
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:407.44

    Ref: TM-T79807

  • Casein kinase 1δ-IN-4
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    Casein kinase 1δ-IN-4

    CAS:
    <p>"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."</p>
    Fórmula:C16H12N6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:320.37

    Ref: TM-T79127

  • Myristoyl tetrapeptide-12
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    Myristoyl tetrapeptide-12

    CAS:
    <p>Myristoyl Tetrapeptide-12 activates SMAD2 and facilitates the association of SMAD3 with DNA, promoting eyelash hair growth [1] [2].</p>
    Fórmula:C32H63N7O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:625.89

    Ref: TM-T80628

  • ROCK-IN-7
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    ROCK-IN-7

    CAS:
    <p>ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].</p>
    Fórmula:C17H17N3O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:327.4

    Ref: TM-T79080

  • Brepocitinib
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    Brepocitinib

    CAS:
    <p>Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).</p>
    Fórmula:C18H21F2N7O
    Pureza:99.82%
    Cor e Forma:Solid
    Peso molecular:389.4

    Ref: TM-TQ0010

  • JAK-IN-26
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    JAK-IN-26

    CAS:
    <p>JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with favorable pharmacokinetic properties, exhibiting potency in</p>
    Fórmula:C22H24N6O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:420.46

    Ref: TM-T78189

  • JAK-IN-5
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    JAK-IN-5

    CAS:
    <p>JAK-IN-5 is a JAK inhibitor.</p>
    Fórmula:C27H31FN6O
    Pureza:98.1% - 99.37%
    Cor e Forma:Solid
    Peso molecular:474.57

    Ref: TM-T11710

  • Casein Kinase II Inhibitor IV
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    Casein Kinase II Inhibitor IV

    CAS:
    <p>Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.</p>
    Fórmula:C24H23N5O3
    Pureza:99.65% - 99.75%
    Cor e Forma:Solid
    Peso molecular:429.47

    Ref: TM-T10687

  • JAK2-IN-4
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    JAK2-IN-4

    CAS:
    <p>JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.</p>
    Fórmula:C23H27N5O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:469.56

    Ref: TM-T11708

  • STAT3-IN-20
    Targetmol
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    STAT3-IN-20

    CAS:
    <p>STAT3-IN-20 (Compound 40), with an IC50 of 0.65 μM, is a selective inhibitor targeting the SH2 domain of STAT3, thereby impeding its phosphorylation, nuclear</p>
    Fórmula:C30H27F4N7S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:593.64

    Ref: TM-T79662

  • STAT6-IN-2
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    STAT6-IN-2

    CAS:
    <p>STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.</p>
    Fórmula:C28H31N5O2
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:469.58

    Ref: TM-T79185

  • H-1152 dihydrochloride
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    H-1152 dihydrochloride

    CAS:
    <p>H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.</p>
    Fórmula:C16H23Cl2N3O2S
    Pureza:99.85%
    Cor e Forma:Solid
    Peso molecular:392.34

    Ref: TM-T35328

  • GNE-7883
    Targetmol
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    GNE-7883

    CAS:
    <p>GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.</p>
    Fórmula:C28H29FN6O2
    Pureza:97.61%
    Cor e Forma:Solid
    Peso molecular:500.57

    Ref: TM-T78558

  • Gossypolone
    Targetmol
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    Gossypolone

    CAS:
    <p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>
    Fórmula:C30H26O10
    Pureza:96.66%
    Cor e Forma:Solid
    Peso molecular:546.52

    Ref: TM-T31987