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Células - tronco e Derivados

Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 695 produtos de "Células - tronco e Derivados"

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  • TCS 21311
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    TCS 21311

    CAS:
    <p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ &amp; GSK3β; &gt;100x selective over JAK1, JAK2, TYK2.</p>
    Fórmula:C27H25F3N4O4
    Pureza:99.39% - ≥98%
    Cor e Forma:Solid
    Peso molecular:526.51

    Ref: TM-T17019

  • Lepzacitinib
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    Lepzacitinib

    CAS:
    <p>Lepzacitinib is a selective, inflammatory, small molecule JAK1/3(Janus kinase) inhibitor primarily used for the treatment of atopic dermatitis.</p>
    Fórmula:C18H21N5O3
    Pureza:99.85%
    Cor e Forma:Solid
    Peso molecular:355.39

    Ref: TM-T78207

  • ROCK2-IN-6 hydrochloride
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    ROCK2-IN-6 hydrochloride

    CAS:
    <p>ROCK2-IN-6 hydrochloride (Comp A)为一种选择性ROCK2抑制剂，适用于研究ROCK介导的疾病、自身免疫性病症与炎症。</p>
    Fórmula:C26H22ClF2N7O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:521.95

    Ref: TM-T78205

  • TGFβ-IN-5
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    TGFβ-IN-5

    CAS:
    <p>TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.</p>
    Fórmula:C20H16N4
    Pureza:99.29% - 99.5%
    Cor e Forma:Solid
    Peso molecular:312.37

    Ref: TM-T77786

  • ROCK-IN-8
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    ROCK-IN-8

    CAS:
    <p>ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research,</p>
    Fórmula:C30H25FN4O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:556.61

    Ref: TM-T79809

  • Nezulcitinib
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    Nezulcitinib

    CAS:
    <p>Nezulcitinib (TD-0903) is an inhaled pan-JAK inhibitor targeting COVID-19-related acute lung injury.</p>
    Fórmula:C30H37N7O2
    Cor e Forma:Solid
    Peso molecular:527.66

    Ref: TM-T63709

  • Chroman 1
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    Chroman 1

    CAS:
    <p>Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM).</p>
    Fórmula:C24H28N4O4
    Pureza:99.67% - 99.84%
    Cor e Forma:Solid
    Peso molecular:436.5

    Ref: TM-T14960

  • BMS-932481
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    BMS-932481

    CAS:
    <p>BMS-932481 is a γ-secretase modulator.</p>
    Fórmula:C24H24FN7O
    Cor e Forma:Solid
    Peso molecular:445.49

    Ref: TM-T26864

  • GSK-3β inhibitor 8
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    GSK-3β inhibitor 8

    CAS:
    <p>GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidine</p>
    Fórmula:C20H20ClN5OS
    Pureza:98.46%
    Cor e Forma:Solid
    Peso molecular:413.92

    Ref: TM-T35556

  • JAK-IN-4
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    JAK-IN-4

    CAS:
    <p>JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model.</p>
    Fórmula:C18H21N4Na2O6P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:466.341

    Ref: TM-T11705

  • ROCK2-IN-2
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    ROCK2-IN-2

    CAS:
    <p>ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of &lt;1 μM).</p>
    Fórmula:C18H12N6OS
    Pureza:99.65%
    Cor e Forma:Solid
    Peso molecular:360.39

    Ref: TM-T12747

  • Casein kinase 1δ-IN-10
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    Casein kinase 1δ-IN-10

    CAS:
    <p>Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).</p>
    Fórmula:C21H17N3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:359.38

    Ref: TM-T79697

  • FM-479
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    FM-479

    CAS:
    <p>FM-479, a structural analog of FM-381, lacks inhibition of JAK3/kinases within 100-300 nM, serving as FM-381's negative control.</p>
    Fórmula:C25H26N6O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:442.523

    Ref: TM-T22333

  • STAT3-IN-B9
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    STAT3-IN-B9

    CAS:
    <p>STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.</p>
    Fórmula:C20H13NO5S
    Pureza:98.19%
    Cor e Forma:Solid
    Peso molecular:379.39

    Ref: TM-T28865

  • TP0427736
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    TP0427736

    CAS:
    <p>TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x &gt; ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.</p>
    Fórmula:C14H10N4S2
    Pureza:97.26%
    Cor e Forma:Solid
    Peso molecular:298.39

    Ref: TM-T24897

  • ML115
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    ML115

    CAS:
    <p>ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.</p>
    Fórmula:C15H15ClN2O4
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:322.74

    Ref: TM-T35544

  • MRK-560
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    MRK-560

    CAS:
    <p>MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.</p>
    Fórmula:C19H17ClF5NO4S2
    Pureza:98.87%
    Cor e Forma:Solid
    Peso molecular:517.92

    Ref: TM-T16133

  • LX7101
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    LX7101

    CAS:
    <p>LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 &lt;1 nM).</p>
    Fórmula:C23H29N7O3
    Pureza:99.08%
    Cor e Forma:Solid
    Peso molecular:451.52

    Ref: TM-T15798

  • Itacnosertib (hydrocholide)
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    Itacnosertib (hydrocholide)

    CAS:
    <p>Itacnosertib hydrochloride acts as an inhibitor targeting JAK2, ACVR1 (ALK2), and ALK5 [1].</p>
    Fórmula:C26H29ClN8O
    Cor e Forma:Solid
    Peso molecular:505.01

    Ref: TM-T84696

  • BMS-983970
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    BMS-983970

    CAS:
    <p>BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.</p>
    Fórmula:C26H26F4N4O3
    Cor e Forma:Solid
    Peso molecular:518.5

    Ref: TM-T14683