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Células - tronco e Derivados

Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 695 produtos de "Células - tronco e Derivados"

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  • WZ-2-033
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    WZ-2-033

    CAS:
    <p>WZ-2-033 is a potent STAT3 inhibitor. It inhibits proliferation, colony survival, migration, and invasion of MDA-MB-231, HCC70, and MDA-MB231-4175 cells, with IC50 values of 0.7, 1.3, and 1.3 μM respectively.</p>
    Fórmula:C25H18F3N3O4S
    Cor e Forma:Solid
    Peso molecular:513.49

    Ref: TM-T200925

  • STAT3-IN-8
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    STAT3-IN-8

    CAS:
    <p>"STAT3-IN-8 (compound H172) is a potent inhibitor of STAT3 with potential applications in cancer research [1]."</p>
    Fórmula:C19H7F7N2O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:444.26

    Ref: TM-T71550

  • PF-06263276
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    PF-06263276

    CAS:
    <p>PF-06263276 selectively inhibits pan-JAK with IC50: JAK1 (2.2 nM), JAK2 (23.1 nM), JAK3 (59.9 nM), TYK2 (29.7 nM).</p>
    Fórmula:C31H31FN8O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:566.63

    Ref: TM-T16488

  • PF-06648671
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    PF-06648671

    CAS:
    <p>PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.</p>
    Fórmula:C25H23ClF4N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:538.92

    Ref: TM-T24621

  • TGFβ1-IN-1
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    TGFβ1-IN-1

    CAS:
    <p>TGFβ1-IN-1 is a TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in cancer research.</p>
    Fórmula:C22H24N2O3
    Pureza:99.89% - 99.89%
    Cor e Forma:Solid
    Peso molecular:364.438

    Ref: TM-T61389

  • GSK-3β inhibitor 20
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    GSK-3β inhibitor 20

    CAS:
    <p>GSK-3β inhibitor20 (compound 3A) is an effective inhibitor of GSK-3β, exhibiting an IC50 value of 74.4 nM.</p>
    Fórmula:C22H21N5O2S
    Cor e Forma:Solid
    Peso molecular:419.50

    Ref: TM-T200457

  • HDAC6-IN-9
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    HDAC6-IN-9

    CAS:
    <p>HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.</p>
    Fórmula:C19H16N2O3
    Pureza:98.84%
    Cor e Forma:Solid
    Peso molecular:320.34

    Ref: TM-T60856

  • DAPM
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    DAPM

    CAS:
    <p>DAPM (gamma-Secretase Inhibitor XVI) is a Notch pathway inhibitor with anticancer activity and antiproliferative effects.</p>
    Fórmula:C20H20F2N2O4
    Pureza:99.76%
    Cor e Forma:Solid
    Peso molecular:390.38

    Ref: TM-T86161

  • Aβ42-IN-1
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    Aβ42-IN-1

    CAS:
    <p>Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).</p>
    Fórmula:C29H27ClN4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:499

    Ref: TM-T10211

  • Tyk2-IN-20
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    Tyk2-IN-20

    CAS:
    <p>Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 nM. Additionally, it inhibits JAK1, JAK2, and JAK3 with IC50 values under 100 nM. This compound is utilized for the research of inflammatory diseases.</p>
    Fórmula:C24H25N7O2
    Cor e Forma:Solid
    Peso molecular:443.50

    Ref: TM-T201155

  • TYK2 ligand 2
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    TYK2 ligand 2

    CAS:
    <p>TYK2ligand 2 is the TYK2 ligand of PROTACTYD-68. TYD-68 is a highly potent and selective CRBN-recruiting TYK2 PROTAC degrader with a DC50 value of 0.42 nM.</p>
    Fórmula:C24H20FN7O4
    Cor e Forma:Solid
    Peso molecular:489.458

    Ref: TM-T206678

  • TEAD-IN-20
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    TEAD-IN-20

    CAS:
    <p>TEAD-IN-20 is a TEAD inhibitor with IC50 values of 0.021 μM in TEAD4 FRET and 0.044 μM in TEAD4 MCF7-Tead cell lines. It has potential applications in cancer research.</p>
    Fórmula:C20H19F3N4O3
    Cor e Forma:Solid
    Peso molecular:420.39

    Ref: TM-T207373

  • Logotipo do CymitQuimica
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    JAK-IN-19

    <p>JAK-IN-19 inhibits JAK (pIC50: 7.2, 7.7), less so for VEGFR2 (7.0) and Aurora B (5.8).</p>
    Fórmula:C26H36FN5O2
    Cor e Forma:Solid
    Peso molecular:469.59

    Ref: TM-T63026

  • iBFAR2
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    iBFAR2

    CAS:
    <p>iBFAR2, an inhibitor of BFAR, restores the CD8+ tumor-resident memory T cell subset against solid tumors. It promotes the binding of JAK2-STAT1 and enhances the phosphorylation of STAT1.</p>
    Fórmula:C19H15F3N2O2
    Cor e Forma:Solid
    Peso molecular:360.33

    Ref: TM-T204531

  • CEE321
    Targetmol
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    CEE321

    CAS:
    <p>CEE321 is an effective pan-JAK inhibitor with an IC50 of 54 nM. It effectively inhibits biomarkers associated with atopic dermatitis.</p>
    Fórmula:C18H16ClN5O
    Cor e Forma:Solid
    Peso molecular:353.806

    Ref: TM-T204824

  • Cenacitinib
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    Cenacitinib

    CAS:
    <p>Cenacitinib is an effective inhibitor of Janus kinase (Janus kinase) and possesses anti-inflammatory activity.</p>
    Fórmula:C19H19F2N7O3
    Cor e Forma:Solid
    Peso molecular:431.40

    Ref: TM-T201149

  • (R)-9b
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    (R)-9b

    CAS:
    <p>(R)-9b is an effective inhibitor of the ACK1 tyrosine kinase (IC50=56 nM) and exhibits anticancer activity. It selectively targets ACK1 but also inhibits kinases in the JAK family, specifically JAK2 and Tyk2. (R)-9b is used in research related to hormone-regulated cancers, such as prostate cancer and breast cancer.</p>
    Fórmula:C20H27ClN6O
    Cor e Forma:Solid
    Peso molecular:402.92

    Ref: TM-T201776

  • Carboxylesterase-IN-3
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    Carboxylesterase-IN-3

    CAS:
    <p>Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.</p>
    Fórmula:C11H6Cl2N4OS
    Pureza:97.49% - 98.47%
    Cor e Forma:Solid
    Peso molecular:313.16

    Ref: TM-T60788

  • STAT3-IN-35
    Targetmol
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    STAT3-IN-35

    CAS:
    <p>STAT3-IN-35 is a STAT3 inhibitor that binds to the SH2 domain. This compound inhibits the phosphorylation of STAT3 and exhibits antiproliferative activity in triple-negative breast cancer (TNBC) cell lines. Additionally, STAT3-IN-35 has demonstrated toxicity and potent antitumor activity in TNBC xenograft models.</p>
    Fórmula:C21H23NO4
    Cor e Forma:Solid
    Peso molecular:353.41

    Ref: TM-T200468

  • YLIU-4-105-1
    Targetmol
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    YLIU-4-105-1

    CAS:
    <p>YLIU-4-105-1 is a type II JAK2 inhibitor. Demonstrating in vivo pharmacological activity, YLIU-4-105-1 reduces splenic weight, decreases blood reticulocyte counts in a dose-dependent manner, and inhibits pSTAT5.</p>
    Fórmula:C32H34F3N7O2
    Cor e Forma:Solid
    Peso molecular:605.65

    Ref: TM-T201176