Células - tronco e Derivados
Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.
Subcategorias de "Células - tronco e Derivados"
- Gama-secretase(67 produtos)
- Hedgehog/Smoothened(49 produtos)
- Via Hippo(7 produtos)
- JAK(246 produtos)
- Porcupine(8 produtos)
- ROCK(61 produtos)
- STAT(104 produtos)
- Células - tronco(129 produtos)
- TGF-beta/Smad(70 produtos)
- Wnt/beta-catenina(65 produtos)
Exibir 2 mais subcategorias
Foram encontrados 436 produtos para "Células - tronco e Derivados".
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ALK5-IN-83
ALK5-IN-83 (compound 13b) is an ALK5 inhibitor with an IC50 of 0.13 μM. It suppresses TGF-β1-induced Smad2 phosphorylation and cell motility in A549 cells.Fórmula:C20H23N7O2SCor e Forma:SolidPeso molecular:425.51Axltide
CAS:Axltide mimics mouse Insulin receptor substrate 1, amino acids 979-989 with sequence KKSRGDYMTMQIG.Fórmula:C63H107N19O20S2Pureza:98%Cor e Forma:SolidPeso molecular:1514.77Tyrosine Kinase Inhibitor Library
A unique collection of xnum HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;Cor e Forma:Odour SolidRef: TM-L2200
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarKinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Cor e Forma:Odour SolidRef: TM-L1600
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarBaricitinib-D3
CAS:Baricitinib-D3 is the deuterated form of Baricitinib. Baricitinib (T2485) (LY3009104; INCB028050) acts as a selective and orally administered inhibitor of JAK1 and JAK2, with IC50 values of 5.9 nM and 5.7 nM, respectively.Fórmula:C16H17N7O2SCor e Forma:SolidPeso molecular:374.44PSEN1-IN-2
PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.Fórmula:C20H18ClFN2O3SCor e Forma:SolidPeso molecular:420.885β-Cholanic acid
CAS:5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.Fórmula:C24H40O2Pureza:98.91% - 99.89%Cor e Forma:White SolidPeso molecular:360.57Epigenetics Compound Library
A collection of xnum wine components, suitable for high-throughput and high-content screening.Cor e Forma:Odour SolidRef: TM-L1200
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarYAP-TEAD-IN-1 acetate
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.Fórmula:C95H148ClN23O23S2Pureza:98.11% - 99.98%Cor e Forma:SoildPeso molecular:2079.92SAHM1
CAS:Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.Fórmula:C94H162N36O23SPureza:98%Cor e Forma:SolidPeso molecular:2196.58FDA-Approved Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.Cor e Forma:LiquidRef: TM-L1610
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarNIBR-LTSi
NIBR-LTSi is a selective LATS kinase inhibitor that also activates YAP signaling, promotes tissue stem cell expansion and tissue regeneration in vitro/vivo.Fórmula:C18H20N4OPureza:99.87%Cor e Forma:Brown SolidPeso molecular:308.38SJ988497
CAS:SJ988497: PROTAC JAK2 degrader, inhibits CRLF2r cell growth, degrades GSPT1, combines Ruxolitinib, linker, Pomalidomide; researched for ALL.Fórmula:C36H36N10O5Cor e Forma:SolidPeso molecular:688.74TGF-β1/Smad3-IN-1
CAS:TGF-β1/Smad3-IN-1 is an orally administrable dual inhibitor of TGF-β1/Smad3 with anti-fibrotic activity, idiopathic pulmonary fibrosis (IPF).Fórmula:C30H34N4O6SPureza:99.83%Peso molecular:578.68LH168
LH168 is a potent and selective probe for WDR5, with a SPR Kd value of 13 nM.Fórmula:C29H31F3N6O2SCor e Forma:SolidPeso molecular:584.66JAK-2/3-IN-1
CAS:JAK-2/3-IN-1 inhibits JAK-2/3 isoforms with sub-250 nM Ki; from US patent US8163732B2.Fórmula:C20H12ClN3OCor e Forma:SolidPeso molecular:345.79WDR5 ligand 2
CAS:WDR5ligand 2 is a ligand for WDR5 and can be utilized in the synthesis of PROTAC WDR5degrader 1.Fórmula:C29H31F3N4O4Cor e Forma:SolidPeso molecular:556.576Povorcitinib phosphate
CAS:Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the treatment of cutaneous lupus erythematosus and Lichen planus.Fórmula:C23H25F5N7O5PPureza:99.57%Cor e Forma:SolidPeso molecular:605.45Ref: TM-T39113L
1mg46,00€5mg96,00€1mL*10mM (DMSO)128,00€10mg145,00€25mg236,00€50mg339,00€100mg460,00€200mg622,00€JAK-IN-33
JAK-IN-33 (Compound 3 (R)) is a selective inhibitor of the Janus kinase (JAK) family [1].Pureza:98%Cor e Forma:Odour SolidJAK2-IN-17
JAK2-IN-17 (compound 20) is a potent allosteric inhibitor of JAK2. It has IC50 values of 160 nM for the full-length JAK2 and 130 nM for JAK2V617F. JAK2-IN-17 covalently modifies Lys677 in the pseudokinase domain.
