Células - tronco e Derivados
Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.
Subcategorias de "Células - tronco e Derivados"
- Gama-secretase(67 produtos)
- Hedgehog/Smoothened(49 produtos)
- Via Hippo(7 produtos)
- JAK(246 produtos)
- Porcupine(8 produtos)
- ROCK(61 produtos)
- STAT(104 produtos)
- Células - tronco(129 produtos)
- TGF-beta/Smad(70 produtos)
- Wnt/beta-catenina(65 produtos)
Exibir 2 mais subcategorias
Foram encontrados 436 produtos para "Células - tronco e Derivados".
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JAK1/STAT3-IN-1
JAK1/STAT3-IN-1 (compound 4f) functions as an anti-atopic dermatitis (AD) agent by inhibiting the JAK1/STAT3 signaling pathway. It has an IC50 value of 2.17 μM for inhibiting NO production. Additionally, JAK1/STAT3-IN-1 improves skin conditions in AD-like mice by reducing inflammatory infiltration, suppressing the expression of p-JAK1/JAK1 and p-STAT3/STAT3, and alleviating the hyperimmune response induced by MC903 (Calcipotriol).Fórmula:C30H33FN4O3SCor e Forma:SolidPeso molecular:548.67JAK1/TYK2-IN-1
CAS:JAK1/TYK2-IN-1 is a dual inhibitor of TYK2 and JAK1 ( IC 50 = 29 and 41 nM respectively).Fórmula:C18H20F3N7OCor e Forma:SolidPeso molecular:407.401FRM-024
CAS:FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment ofFórmula:C22H22ClN5O2Cor e Forma:SolidPeso molecular:423.9SJ10542
CAS:SJ10542: potent JAK2/3-targeting PG-PROTAC; DC50s: JAK2 - 14 nM, JAK3 - 11 nM, JAK2-fusion ALL - 24 nM; CRBN recruiter.Fórmula:C41H46N12O5SCor e Forma:SolidPeso molecular:818.95Itacitinib adipate
CAS:Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.Fórmula:C32H33F4N9O5Cor e Forma:SolidPeso molecular:699.66Anti-5T4/TPBG Antibody (9P872)
Anti-5T4/TPBG Antibody (9P872) is an antibody targeting 5T4/TPBG. Anti-5T4/TPBG Antibody (9P872) can be used in ELISA, FCM.Cor e Forma:Odour LiquidAnti-NANOG Antibody (1M448)
Anti-NANOG Antibody (1M448) is a Mouse antibody targeting NANOG. Anti-NANOG Antibody (1M448) can be used in ELISA, WB, ICC, IF, FCM.Pureza:>95%Cor e Forma:Odour LiquidAnti-SOST Antibody (3R170)
Anti-SOST Antibody (3R170) is an antibody targeting SOST. Anti-SOST Antibody (3R170) can be used in ELISA, IHC.Cor e Forma:Transparent LiquidIBS008738
CAS:IBS008738 is a TAZ activator that stabilises TAZ and increases unphosphorylated TAZ levels in C2C12 cells, upregulates MyoD-dependent gene transcription.Fórmula:C22H22N4O2Pureza:99.44%Cor e Forma:Yellow SolidPeso molecular:374.44Legumain inhibitor 1
CAS:Legumain inhibitor 1 is a highly potent and specific Legumain inhibitor with potential anticancer activity for cancer research.Fórmula:C23H25N5O4SPureza:98.14%Cor e Forma:Yellow SolidPeso molecular:467.54YAP/TAZ inhibitor-1
CAS:YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor (IC50 <0.100 μΜ) for the study of abnormal immune function and cancer.Fórmula:C33H39N3O5S2Pureza:99.72%Cor e Forma:White SolidPeso molecular:621.81DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Fórmula:C26H35N7O5Cor e Forma:SolidPeso molecular:525.6CHZ868
CAS:CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.Fórmula:C22H19F2N5O2Pureza:99.38%Cor e Forma:SolidPeso molecular:423.42γ-secretase modulator 3
CAS:Gamma-secretase modulator 3 (γ-secretase modulator 3) is a γ-secretase modulator that reduces Aβ production.Fórmula:C24H23FN4OSPureza:98%Cor e Forma:SolidPeso molecular:434.53Enoticumab
CAS:Enoticumab (REGN421) is a fully human IgG1 monoclonal antibody with anticancer activity that inhibits cancer cell growth.Pureza:98.2% (SDS-PAGE); 98.9% (SEC-HPLC) - 98.2% (SDS-PAGE); 98.9% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.22 kDaAtinvicitinib
CAS:Atinvicitinib, a selective JAK1 inhibitor, blocks cytokine signaling, modulating itch, allergy, and inflammatory responses, immune and therapeutic studies.Fórmula:C16H17FN6O3Pureza:99.36%Cor e Forma:White SolidPeso molecular:360.35Ref: TM-T39646
1mg138,00€1mL*10mM (DMSO)264,00€5mg334,00€10mg550,00€25mg1.063,00€50mg1.738,00€100mg2.547,00€Ilunocitinib
CAS:Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.Fórmula:C17H17N7O2SPureza:99.88%Cor e Forma:SolidPeso molecular:383.43Ref: TM-T38571
1mg92,00€5mg230,00€1mL*10mM (DMSO)251,00€10mg356,00€25mg713,00€50mg1.189,00€100mg1.791,00€200mg2.412,00€Ifidancitinib
CAS:Ifidancitinib (ATI-50002) is a JAK kinase 1/3 inhibitor used to study autoimmune diseases.Fórmula:C20H18FN5O3Pureza:98.05%Cor e Forma:SolidPeso molecular:395.39Anti-GPC3 Antibody (4L576)
Anti-GPC3 Antibody (4L576) is an antibody targeting GPC3. Anti-GPC3 Antibody (4L576) can be used in ELISA, WB, IF.Cor e Forma:Odour LiquidBaricitinib
CAS:Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. Cost-effective and quality-assured.Fórmula:C16H17N7O2SPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:371.42Ref: TM-T2485
5mg48,00€1mL*10mM (DMSO)65,00€10mg70,00€25mg95,00€50mg109,00€100mg137,00€200mg178,00€500mg295,00€
