Células - tronco e Derivados
Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.
Subcategorias de "Células - tronco e Derivados"
- Gama-secretase(68 produtos)
- Hedgehog/Smoothened(49 produtos)
- Via Hippo(7 produtos)
- JAK(246 produtos)
- Porcupine(8 produtos)
- ROCK(61 produtos)
- STAT(104 produtos)
- Células - tronco(129 produtos)
- TGF-beta/Smad(70 produtos)
- Wnt/beta-catenina(65 produtos)
Exibir 2 mais subcategorias
Foram encontrados 437 produtos para "Células - tronco e Derivados".
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GDC-0214
CAS:GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Fórmula:C28H28ClF2N9O3Pureza:99.75%Cor e Forma:White SolidPeso molecular:612.03Ref: TM-T9826
1mg93,00€5mg182,00€1mL*10mM (DMSO)245,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.099,00€FM-381
CAS:FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.Fórmula:C24H24N6O2Pureza:98.44%Cor e Forma:SolidPeso molecular:428.49Ref: TM-T5091
1mg47,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)107,00€10mg128,00€25mg212,00€50mg319,00€100mg485,00€JANEX-1
CAS:JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Fórmula:C16H15N3O3Pureza:98% - 99.81%Cor e Forma:SolidPeso molecular:297.31WHI-P97
CAS:WHI-P97 is a rationally designed potent inhibitor of JAK-3.Fórmula:C16H13Br2N3O3Pureza:99.93%Cor e Forma:SolidPeso molecular:455.1Pacritinib hydrochloride
CAS:Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.Fórmula:C28H32N4O3·xClHCor e Forma:SolidPeficitinib
CAS:Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.Fórmula:C18H22N4O2Pureza:98.67% - 99.89%Cor e Forma:SolidPeso molecular:326.39Ref: TM-T6933
2mg38,00€5mg63,00€1mL*10mM (DMSO)70,00€10mg99,00€25mg172,00€50mg268,00€100mg416,00€200mg610,00€Cucurbitacin I
CAS:Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.Fórmula:C30H42O7Pureza:96.69% - 99.8%Cor e Forma:SolidPeso molecular:514.65Pyridone 6
CAS:Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).Fórmula:C18H16FN3OPureza:97.1% - 98.74%Cor e Forma:SolidPeso molecular:309.34Ref: TM-T3080
1mg50,00€2mg71,00€5mg105,00€1mL*10mM (DMSO)110,00€10mg173,00€25mg358,00€50mg587,00€100mg888,00€200mg1.198,00€Lumiflavine
CAS:Lumiflavine (Lumilactoflavin) inhibits riboflavin uptake. It is produced by the photolysis of vitamin B2.Fórmula:C13H12N4O2Pureza:97.09% - 98.01%Cor e Forma:Yellow SolidPeso molecular:256.26XMU-MP-1
CAS:XMU-MP-1 is a reversible and selective MST1/2 kinase inhibitor, IC50 values for MST1 and MST2 are 71.1 nM and 38.1 nM, respectively. High-Quality, Low-Cost!Fórmula:C17H16N6O3S2Pureza:99.68% - 99.97%Cor e Forma:SolidPeso molecular:416.48Ref: TM-T4212
1mg50,00€2mg74,00€1mL*10mM (DMSO)89,00€5mg92,00€10mg144,00€25mg289,00€50mg485,00€100mg628,00€ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Fórmula:C23H25NO·HClPureza:98.05% - 99.48%Cor e Forma:White SolidPeso molecular:367.91SRI-011381 hydrochloride
CAS:SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.Fórmula:C20H32ClN3OPureza:99.32% - 99.41%Cor e Forma:SolidPeso molecular:365.94Ref: TM-T5129
1mg34,00€2mg44,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg105,00€25mg215,00€50mg334,00€100mg497,00€200mg755,00€2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.Fórmula:C16H13Cl2N3O2Pureza:98.77%Cor e Forma:White SolidPeso molecular:350.2LY900009
CAS:LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.Fórmula:C23H27N3O4Pureza:97.07%Cor e Forma:SolidPeso molecular:409.48Ref: TM-T9015
1mg35,00€5mg80,00€1mL*10mM (DMSO)87,00€10mg112,00€25mg197,00€50mg290,00€100mg420,00€200mg590,00€Deucravacitinib
CAS:Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Fórmula:C20H19D3N8O3Pureza:98.52% - >99.99%Cor e Forma:SolidPeso molecular:425.46Ref: TM-T14687
1mg56,00€5mg137,00€1mL*10mM (DMSO)149,00€10mg248,00€25mg389,00€50mg575,00€100mg817,00€BMS-911543
CAS:BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.Fórmula:C23H28N8OPureza:97.69% - 99.97%Cor e Forma:SolidPeso molecular:432.52MK-0752 Sodium
CAS:Sodium MK-0752 is a novel and potent gamma-secretase inhibitor that has been evaluated in clinical trials for the treatment of various types of cancer.Fórmula:C21H21ClF2NaO4SCor e Forma:SolidPeso molecular:465.89BIO-013077-01
CAS:BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.Fórmula:C17H13N5Pureza:99.87%Cor e Forma:SolidPeso molecular:287.32Ref: TM-T8330
1mg48,00€5mg96,00€1mL*10mM (DMSO)131,00€10mg133,00€25mg259,00€50mg371,00€100mg527,00€200mg713,00€FLLL32
CAS:FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).Fórmula:C28H32O6Pureza:97.90% - 99.10%Cor e Forma:SolidPeso molecular:464.55Ref: TM-T6838
2mg43,00€5mg63,00€1mL*10mM (DMSO)69,00€10mg88,00€25mg117,00€50mg187,00€100mg333,00€500mg797,00€Gusacitinib HCl
CAS:Gusacitinib (ASN-002/EN-3351), a potent SYK/JAK inhibitor, has strong antitumor activity in various cancers.Fórmula:C24H29ClN8O2Cor e Forma:SolidPeso molecular:497
