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Methylation of a saccharide with a methyl group is called methylation. The process is used in the synthesis of many important molecules, including biomedically-relevant compounds such as drugs and natural products. Methylation can be achieved by using various methods, such as by using an organometallic (e.g., Grignard reagent) or electrophilic reagent (e.g., dimethyl sulfate).

Synthesized by the action of zinc chloride on tetra-O-acetylmannose and 1-chloro-3,4,6- tri-0-acetylmannose.  Isolated from partial acetolysates of baker's yeast mannan and Saccharomyces rouxii mannan.

2-Formylphenyl b-D-glucopyranoside is a phenolic compound that has been shown to have high resistance to transport. It has been shown to possess surface methodology and this property can be used for the delivery of compounds. 2-Formylphenyl b-D-glucopyranoside has also been shown to inhibit plant enzyme activities such as detoxification enzymes and carbohydrate chemistry, which are important in the uptake of natural compounds. In addition, it is able to bind with amines and hydroxyl groups on cells, which may be due to its receptor cell properties. 2-Formylphenyl b-D-glucopyranoside can be synthesized by reacting trifluoroacetic acid with an amine and a hydroxyl group in the presence of glycol ethers or natural compounds.

2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose (IDFP) is a natural compound that has been shown to have pharmacological properties. It is an inhibitor of the enzyme alpha-glucosidase and may be used as a treatment for diabetes mellitus type II. IDFP binds to the active site of the enzyme α-glucosidase, preventing access of the substrate glucose. This causes a decrease in blood glucose levels and has also been shown to reduce cholesterol levels in mice. IDFP is synthesized by reacting ethylene diamine with 2,3:4,5-di-O-isopropylidene b -D -fructofuranose. This reaction produces a heterocycle that undergoes asymmetric synthesis using sodium hydroxide solution and hydrogen fluoride as catalysts.

N-Methyl-D-glucosamine is a nucleotide that is found in the adenine nucleotide pool. It can be synthesized from glucose, which is converted to glucosamine-6-phosphate by the enzyme glucosamine synthetase. This compound can also be obtained from dietary sources. N-Methyl-D-glucosamine has been shown to have cytotoxic activity against mouse tumor cells and inhibit skin cancer in mice. It binds with DNA and inhibits cell growth through a glycosidic bond with terminal residues of DNA, preventing transcription and replication. N-Methyl-D-glucosamine has also been shown to inhibit the growth of resistant microorganisms such as C. glabrata, including antibiotic resistant strains, and bacteria such as E. coli and P. aeruginosa when used in combination with an experimental model of biocompatible polymers.
NMTG has been shown to

Methyl 3,5-di-O-(p-chlorobenzoyl)-2-deoxy-b-D-ribofuranoside is a synthetic oligosaccharide. It has been synthesized by the modification of the glycosylation site on an existing saccharide with a methyl group and fluorination at the 3’ position. This molecule is a monosaccharide with a p-chlorobenzoyl group attached to its 2’ position.

Lacto-N-triose I is a carbohydrate antigen that is used as an acceptor in the synthesis of trisaccharides. Lacto-N-triose I has been shown to have acidic hydrolysis and gel permeation chromatography. It can be used for the synthesis of oligosaccharides, which are important for glycosylation reactions. Lacto-N-triose I also has a glycosylation reaction that can be activated by desulfurization.

An α-anomer, obtained by crystallization at low temperature, can be dehydrated to stable form above 130°C or an unstable (hygroscopic) form at lower temperatures. An example of the applications for α-Lactose monohydrate is in dry powder inhalers.  These are devices that deliver medication to the lung in the form of a dry powder generating an aerosol directly from the drug powder or mixture, using an excipient such as lactose monohydrate.

2,5-Di-O-acetyl-3-C-methyl-D-lyxono-1,4-lactone is a hydrogen bonded lactone. The crystal structure of the compound has been determined by X-ray crystallography and found to be a hydrogen bonded dimer with two molecules of water located between the two monomers. This compound is also known as 3,6,9,12,15,18,21 hexaoxahexacontane 1,4-lactone or DAL.

a-​glucosidase inhibitor

Losartan N2-glucuronide is a custom synthesis that has been modified by fluorination, methylation, and monosaccharide modification. It is synthesized with click chemistry to create an oligosaccharide. This product is synthesized from saccharides (carbohydrates) and polysaccharides. Losartan glucuronide is a complex carbohydrate that has been glycosylated and sugar modified for high purity.

Curdlan is a microbial polysaccharide produced by a mutant strain of Alcaligenes faecalis var. myxogenes which was first shown to produce succinoglucan prior to mutation. Curdlan is a β-1,3 glucan forming clear solutions at about 55 °C which then gels (“low-set”) when cooled. Suspensions of curdlan at higher temperatures form firm resilient gels (“high set”) that melt at 140 - 160 °C.
The image was kindly provided by Dr. Chris Lawson.

3,5-Dimethyl-D-fructose is a glycosylation product of 3,5-dimethoxy-4-hydroxybenzoic acid and D-glucose. It can be synthesized by the reaction of 3,5-dimethoxy-4-hydroxybenzoic acid with D-glucose in the presence of sodium cyanoborohydride. This product has been used as a reactant in click chemistry and as a fluorinating agent for saccharides. 3,5-Dimethyl-D-fructose is a custom synthesis that can be ordered in high purity at CAS No. 52674-57-6.br>br>
3,5 - Dimethyl - D - fructose
is an oligosaccharide that is used as an intermediate in the synthesis of other sugars. This product has been shown to have antiinflammatory properties due to its inhibition of prostaglandin synthesis.br

6-Azido-6-deoxy-1,2:3,5-bisisopropylidene-D-glycero-L-guloheptitol is a synthetic monosaccharide that can be used for the synthesis of oligosaccharides and complex carbohydrates. It is prepared by the fluorination of 6,6'-azido-1,2:3,5 bisisopropylidene D-glycero L guloheptitol. The chemical name of 6,6'-azido 1,2:3,5 bisisopropylidene D glycero L guloheptitol is 2-(6'-Amino)-2-(6'-deoxy)-1-(isopropylidene)ethanol. This compound has been shown to react with carbonyl groups in sugar molecules to form new compounds called glycosides. 6,6'-Amino 1,

Cellobionic acid is produced by oxidative enzymes working on cellulose.  These compounds have found application in cosmetic antiaging formulations, moisturizers, and peels, and in treatment products to improve hyperpigmentation and acne. The bionic acids such as cellobionic acid offer the benefits of α-hydroxyacids without irritation. They also provide additional antioxidant/chelation, barrier strengthening, and moisturizing effects.

A2F N-Glycan is an oligosaccharide that is found in the human body. It is a glycan that has been shown to be involved in a number of biological processes, including effector functions, site specific recognition, diagnosis, and biopharmaceutical production. A2F N-glycan has also been shown to have potential as a biomarker for autoimmune diseases and cancer. The A2F N-glycan profile may differ between patients with different cancers or autoimmune disorders. This difference in the A2F N-glycan profile may contribute to the development of personalized medicine by helping to diagnose these conditions and predict their prognosis.

2,3-O-Isopropylidene-hamamelono-1,4-lactone is an Oligosaccharide with a Glycosylation that is Synthetic and Fluorinated. It has a Custom synthesis and Methylation. This product is Monosaccharide and Polysaccharide. It has a Click modification, a complex carbohydrate, and is High purity. The CAS number for this product is 62968-07-1.

Competitive inhibitor of glucosylceramidase (GlcCer), which catalyses the first step in glycosphingolipid (GSL) synthesis. This compound is a promising candidate for substrate reduction therapy in Sandhoff disease, where it decreases the rate of GSL biosynthesis and counterbalances the impaired rate of ganglioside catabolism.