Terpenoides e Derivados

<p>Oxygen-heterocyclic compound</p>

Carboxylic acid with alcohol function

Lactone

Aldehyde phenol

Lactone

Cyclic alcohol

Lactone

Lactone

Oxygen-heterocyclic compound

Oxygen-heterocyclic compound

Alicyclic ketone

Aromatic hydrocarbon

Alicyclic hydrocarbon

Lactone

Oxygen-heterocyclic compound

Lactone

Oxygen-heterocyclic compound

Alicyclic ketone

Epoxide

Carboxylic acid with alcohol function

Alicyclic monobasic carboxylic acid

<p>Lactone</p>

Unsaturated acyclic monobasic carboxylic acid

Aromatic ketone

Ketone alcohol

Alicyclic hydrocarbon

Lactone

Oxygen-heterocyclic compound

Lactone

Lactone

Lactone

Oxygen-heterocyclic compound

Aromatic hydrocarbon

Lactone

Lactone

Lactone

Alicyclic ketone

Cyclic alcohol

<p>Applications Triterpenoid which can inhibit the proliferation of leukemia HL-60 cells.<br>References Cho, J., et al.: Pulmon. Pharmacol. Ther., 23, 190 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Saha, S., et al.: J. Agric. Food Chem., 58, 434 (2010),<br></p>

<p>Applications Octocrylene-13C3 is the labelled form of Octocrylene (O239755). Octocrylene is a UV-A and UV-B filter used in sunscreen and topical drug formulations.<br>References Lacatusu, I. et al.: Chem. Eng. J., 246, 311 (2014); Allen, J. et al.: Chem. Res. Tox., 9, 605 (1996)<br></p>

<p>Applications Piperitone is a monoterpene compound that has a fresh minty camphor-like odour, and naturally occurs in extracts of commercial oil of peppermint. Piperitone is also used as a starting material in the synthesis of Thymol (T413000), a phenolic compound that is used for its antibacterial properties.<br>References Abdolpour, F., et al.: Pharm. Bio., 45, 230 (2007); Burbott, A., et al.: Phytochemistry, 22, 2227 (1983); Evans, J. &amp; Martin, S.: Curr. Micro., 41, 336 (2000); Ravid, U., et al.: Flav. Frag. J., 9, 85 (1994)<br></p>

<p>Stability Hygroscopic<br>Applications Ginsenoside Rc displays anti-proliferative effects in human breast cancer cell lines.<br>References Lee, Y. et al.: Arch. Pharm. Res., 26, 53 (2003);<br></p>

<p>Applications Labelled Paclitaxel (P132500). An antineoplastic. Used in the study of structure and function of microtubles into tubulin.<br>References Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984), Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984), Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995), Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002), Stone, G.W., et al.: N. Engl. J. Med., 350, 221 (2004),<br></p>

<p>Abietic Acid (Sylvic acid) is a diterpene extracted from Pimenta racemosavar. Cost-effective and quality-assured.</p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Intermediate in the biosynthesis of carotenoids.<br>References Umeno, D. &amp; Arnold, F.; J. Bacteriol. 186, 1531 (2004).<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 15-cis-Phytoene is an intermediate in the biosynthesis of carotenoids.<br>References Davidovich-Rikanati, R., et al.: Plant J., 56, 228 (2008), Puri, A., et al.: Weed Sci., 57, 482 (2009), Serino, S., et al.: J. Agric. Food Chem., 57, 8753 (2009),<br></p>

<p>Applications Tetradecane is a biomarker in dog hair for visceral leishmaniasis.<br>References Magalhaes-Junior, J.T., et. al.: Anal. Bioanal. Chem., 406, 6691 (2014)<br></p>

<p>Applications Labelled Paclitaxel (P132500). An antineoplastic. Used in the study of structure and function of microtubles into tubulin.<br>References Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984), Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984), Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995), Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002), Stone, G.W., et al.: N. Engl. J. Med., 350, 221 (2004),<br></p>

<p>Applications Cyclopentyl chloride (cas# 930-28-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Labelled Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Artursson., et al.: J. Pharma. Sci., 73, 1507 (1984), Fu., et al.: Pharma. Res., 17, 100 (2000),<br></p>

<p>Stability Hygroscopic<br>Applications Midostaurin was shown to possess antiproliferative characteristics via inhibition of protein kinase C, kinase insert domain receptor, and c-kit.<br>References Tahtouh, T., et al.: J. Med. Chem., 55, 9312 (2012); Pedeboscq, S., et al.: PLoS. One., 7, 36811 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications Ginsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia.<br>References Zhang, X. et al.: Neurochem. Res., 39, 1363 (2014); Zhu, D. et al.: J. Neurosci. Res., 92, 1217 (2014);<br></p>

<p>Stability Light Sensitive<br>Applications An aroma compound commonly found in essential oils such as rose oil. It is an important fragrance chemical used in perfumery. β-Ionone is effective in the chemoprevention of rat mammary carcinogenesis.<br>References Bondar, C. et al.: Cosm. Toil., 122, 73 (2007); Yu, S. et al.: J. Agric. Food Chem., 43, 2144 (1995); Zhou, R. et al.: Jing. Huag., 28, 253 (2011);<br></p>

<p>Applications cis-Nerolidol is one of the main component in the essential oils from fresh aerial parts of Thymus ciliatus (Lamiaceae). Also, it is a terpene that displays high potency on the contractility of cardiac muscle in guinea pig left atrium. A potential and effective treatment for malaria.<br>References Cherchar, H., et al.: Mor. J. Chem., 2, 85-89 (2014); Vasconcelos, C. M. L., et al.: Nat. Prod. Res., (2017); Saito, A. Y., et al.: Int. J. Antimicrob. Agents, 48, 641-646 (2016)<br></p>

<p>Applications 9-cis-Retinyl Linoleate is a fatty acid ester of Retinol isomer.<br></p>

<p>Applications Nerolidol (cas# 40716-66-3) is a terpene standard found in cannabis.<br></p>

<p>Applications Retinoic Acid 3,3-Dimethyl-2-oxobutyl Ester, is a Retinoic Acid derivative that has shown to be used for treatment of dermatological disorders.<br>References Mealy, N. E., et al.: Drugs of the Future, Vol.29, P:393-436 (2004);<br></p>

<p>Stability Light Sensitive<br>Applications One of the naturally occurring forms of Vitamin E. Most abundant Tocopherol in soybean and corn oils.<br>References Emerson, et al.: Science, 83, 421 (1936), Bieri, J.G., et al.: J. Nutr., 104, 850 (1974), Jiang, Q., et al.: Am. J. Clin. Nutr., 74, 714 (2001),<br></p>

<p>Applications 4-Methylbenzylidene camphor (4-MBC) is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, specifically UV B radiation. 4-MBC a UV-B ray filter, is an endocrine disruptors (ED).<br>References Schlumpf, M., et al.: Toxicology, 199, 109 (2004), Durrer, S., et al.: Endocrinology, 146, 2130 (2005), Seidlova-Wuttke, D., et al.: Toxicol. Appl. Pharmacol., 214, 1 (2006), Maerkel, K., et al.: Toxicol. Appl. Pharmacol., 218, 152 (2007),<br></p>

<p>Applications A precursor to Paclitaxel.<br></p>

<p>Applications (3R,4R,4aS,7R,8S,8aR)-Hexahydro-3-hydroxy-4,7-dimethyl-8-(3-oxobutyl)-1,2-benzodioxin-8a(3H)-carboxaldehyde is an impurity of Artesunate (A777800).<br>References Baker, J.K., et al.: Pharmaceut. Res., 10, 662 (1993),<br></p>

<p>Applications Gibberellenic Acid is a derivative of Gibberellic Acid (G377450) and is used for plant-growth stimulation.<br>References Pryce, R.J., et al.: Phytochemistry, 12, 507 (1973); Brian, P.W., et al.: Phytochemistry, 6, 1475 (1967)<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 9 is a form of vitamin K2 which acts as a prothrombogenic agent and is also a functional electron transfer component in nitrate reductase.<br>References Hugenholtz, P., et al.: J. Bacteriol., 180, 4765 (1998), Ginet, N., et al.: Biochemistry, 40, 1812 (2001), Cape, J., et al.: J. Biol. Chem., 280, 34654 (2005),<br></p>

<p>Applications Spirotetramat Metabolite BYI08330-​cis-​enol is a metabolite and can be used as analyte in analytical and biological studies for multi-residue method for determination of pesticides and pesticide metabolites in honeybees by liquid and gas chromatography coupled with tandem mass spectrometry, used to investigate honeybee poisoning incidents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kiljanek, T., et al.: J Chromatgr A, 1435, 100 (2016)<br></p>

<p>Applications Labelled Campesterol (C155360). A phytosterol, which may inhibit the intestinal absorption of cholesterol.<br>References Fransen, H., et al.: J. Nut., 140, 1062 (2010), Kojoma, M., et al.: Plant Biotechnol., 27, 59 (2010), Orozco-Solano, M., et al.: J. Agric. Food Chem., 58, 7539 (2010),<br></p>

<p>Applications The natural isomer of the abscission-accelerating plant hormone.<br>References Krochko, J.E., et al.: Plant Physiol., 118, 849 (1998), Jacobsen, J.V., et al.: Psysiol. Plant., 115, 428 (2002),<br></p>

<p>Impurity Paclitaxel - Impurity K<br>Applications Protected Paclitaxel. Paclitaxel - Impurity K.<br>References Kerns, E., et al.: J. Nat. Products, 57, 1391 (1994), Golik, J., et al.: Bioorg. Med. Chem. Lett., 6, 1837 (1996),<br></p>

<p>Applications Gamma Oryzanol is a mixture of 6 substances derived from rice bran oil, including sterols and ferulic acid, called Cycloartanyl Ferulate or Triterpene alcohol ferulate. It has been approved in Japan for several conditions, including menopausal symptoms, mild anxiety, stomach upset, and high cholesterol. In the US, it is widely used as a sports supplement, as well as for reducing cholesterol.Gamma Oryzanol is widely used as a food additive, pharmaceutical material. In cosmetic area, the application to creams and sunscreens exploiting its skin age resistor function and ultraviolet absorbing effect.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Somogyi, M., et al.: J. Biol. Chem., 195, 19 (1952), Wiseman, H., et al.: Biochemical. J., 313, 17 (1996), Banchuen, J., et al.: J. Agricul. Sci., 2009, 42, 191 (2009),<br></p>