CAS 106463-17-6

Tamsulosin Hydrochloride

Description:

Tamsulosin Hydrochloride is a selective alpha-1 adrenergic antagonist primarily used in the treatment of benign prostatic hyperplasia (BPH) to alleviate urinary symptoms. It works by relaxing the smooth muscles in the prostate and bladder neck, facilitating easier urination. The substance is typically administered orally and is known for its relatively high bioavailability and moderate protein binding. Tamsulosin is characterized by its chemical formula, which includes a sulfonamide group, contributing to its pharmacological activity. The compound exhibits a half-life that allows for once-daily dosing, making it convenient for patients. Common side effects may include dizziness, headache, and orthostatic hypotension, particularly upon initiation of therapy. Tamsulosin Hydrochloride is classified as a prescription medication and should be used under medical supervision, especially in patients with a history of cardiovascular issues. Its safety profile and efficacy have been established through various clinical trials, making it a widely prescribed option for managing urinary symptoms associated with prostate enlargement.

Formula: C₂₀H₂₈N₂O₅S·ClH

InChI: InChI=1S/C20H28N2O5S.ClH/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24;/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24);1H/t15-;/m1./s1

InChI key: InChIKey=ZZIZZTHXZRDOFM-XFULWGLBSA-N

SMILES: S(N)(=O)(=O)C1=C(OC)C=CC(C[C@H](NCCOC2=C(OCC)C=CC=C2)C)=C1.Cl

Synonyms:

• (-)-(R)-5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide hydrochloride
• (-)-Ly 253352
• (-)-Ym 12617
• (R)-(-)-Ym 12617
• 5-(2-{[2-(2-Ethoxyphenoxy)Ethyl]Amino}Propyl)-2-Methoxybenzenesulfonamide Hydrochloride
• 5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride
• Benzenesulfonamide, 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, hydrochloride (1:1)
• Benzenesulfonamide, 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, monohydrochloride
• Benzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, monohydrochloride, (R)-
• Dynapress
• Flomax
• Harnal
• Ly 253351
• Omnic
• Tamsulosin HCL
• Tamuzosin hydrochloride
• Urimax
• Uripro
• Ym 12617-1
• Ym 617
• Yutanal
• idehydrochloride
• r-(-)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonam
• (r)-onohydrochlorid
• PRADIF
• 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxy-,monohydrochloride,(r)-benzenesulfonamid
• TAMSULOSIN, HYDROCHLORIDE 99.5%
• (-)-ym12617
• TAMSULOSIN HYDROCHLORIDE
• TAMSOLUSIN HYDROCHLORIDE
• (-)-ly253352
• 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxy-benzenesulfonamidm

Tamsulosin Hydrochloride

CAS: 106463-17-6

Formula: C₂₀H₂₉ClN₂O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 444.9727

Ref: IN-DA00HATB

Tamsulosin Hydrochloride

CAS: 106133-20-4, 106463-17-6

Formula: C₂₀H₂₈N₂O₅S·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 444.97

Ref: 3B-T2749

Tamsulosin hydrochloride, 98+%

CAS: 106463-17-6

An alpha-1 adrenoceptor antagonist

Formula: C₂₀H₂₉ClN₂O₅S

Purity: 98+%

Color and Shape: Powder, White to pale cream, Powder, White to pale cream

Molecular weight: 444.97

Ref: 02-J61999

TAMSULOSIN RACEMATE CRS

CAS: 106463-17-6

TAMSULOSIN RACEMATE CRS

Ref: 41-Y0000653

Tamsulosin hydrochloride

CAS: 106463-17-6

Tamsulosin hydrochloride

Formula: C₂₀H₂₈N₂O₅SHCl

Purity: 99.9%

Color and Shape: White To Off-White

Molecular weight: 444.14857

Ref: 47-876

Tamsulosin hydrochloride impurity standard

CAS: 106463-17-6, 112101-75-4, 116091-63-5, 116091-64-6, 80223-96-7

Tamsulosin hydrochloride impurity standard

Color and Shape: White To Off-White

Ref: 47-877

TAMSULOSIN HYDROCHLORIDE CRS

CAS: 106463-17-6

TAMSULOSIN HYDROCHLORIDE CRS

Formula: C₂₀H₂₉ClN₂O₅S

Color and Shape: White. Powder.

Molecular weight: 444.9727

Ref: 41-Y0000650

Tamsulosin Hydrochloride

CAS: 106463-17-6

Sulfonamides used as drugs

Formula: C₂₀H₂₈N₂O₅S·HCl

Color and Shape: White Off-White Powder

Molecular weight: 408.17189

Ref: 45-1643260

Tamsulosin hydrochloride

CAS: 106463-17-6

Tamsulosin hydrochloride (Flomax hydrochloride) is the hydrochloride salt of tamsulosin, a sulfonamide derivative with α1 adrenergic antagonist activity.

Formula: C₂₀H₂₉ClN₂O₅S

Purity: 95.45% - 99.95%

Color and Shape: White To Off-White Solid

Molecular weight: 444.97

Ref: TM-T0210

Tamsulosin hydrochloride

CAS: 106463-17-6

Tamsulosin hydrochloride

Purity: ≥95%

Molecular weight: 444.97g/mol

Ref: 54-BUP16222

Tamsulosin HCl

CAS: 106463-17-6

Formula: C₂₀H₂₈N₂O₅S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 408.51 36.46

Ref: 4Z-T-122

Tamsulosin hydrochloride

CAS: 106463-17-6

Formula: C₂₀H₂₈N₂O₅S·HCl

Purity: 98.0 - 101.5 % (dried basis)

Color and Shape: White or almost white crystalline powder

Molecular weight: 444.97

Ref: 7W-GP0811

Tamsulosin-d4 HCl

CAS: 106463-17-6

Formula: C₂₀H₂₄D₄N₂O₅S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 412.54 36.46

Ref: 4Z-T-121

Tamsulosin Hydrochloride

CAS: 106463-17-6

Tamsulosin Hydrochloride

Purity: 98%

Molecular weight: 444.97g/mol

Ref: 54-OR1026371

Tamsulosin hydrochloride, EP grade

CAS: 106463-17-6

Formula: C₂₀H₂₈N₂O₅S·HCl

Purity: ≤ 0.1% (Impurity G)

Color and Shape: White or almost white powder

Molecular weight: 444.97

Ref: 7W-GP8711

(R)-(-)-Tamsulosin-d5 HCl(ethoxy-d5)

CAS: 106463-17-6

Purity: 99 atom % D

Molecular weight: 450.00

Ref: 3U-D7543

Tamsulosin Hydrochloride

CAS: 106463-17-6

Color and Shape: Neat

Ref: 86-MM0938.00

(R)-Tamsulosin-d4 Hydrochloride

Controlled Product

CAS: 106463-17-6

Applications (R)-Tamsulosin-d4 Hydrochloride is the labeled analogue of (R)-Tamsulosin Hydrochloride (T006350), a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.
References Kawabe, K., et al.: J. Urol., 144, 908 (1990); Abrams, P., et al.: Br. J. Urol., 76, 325 (1995); Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004)

Formula: C₂₀H₂₅D₄ClN₂O₅S

Color and Shape: Neat

Molecular weight: 449.0

Ref: TR-T006354

(R)-Tamsulosin Hydrochloride

CAS: 106463-17-6

Applications (R)-Tamsulosin is a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.
References Kawabe, K., et al.: J. Urol., 144, 908 (1990), Abrams, P., et al.: Br. J. Urol., 76, 325 (1995), Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004),

Formula: C₂₀H₂₈N₂O₅S·ClH

Color and Shape: White To Off-White

Molecular weight: 444.97

Ref: TR-T006350

Tamsulosin Hydrochloride

CAS: 106463-17-6

Formula: C₂₀H₂₈N₂O₅SHCl

Molecular weight: 408.51 : 36.5

Ref: ST-EA-CP-T7011

(R)-Tamsulosin HCl - Bio-X ™

CAS: 106463-17-6

(R)-Tamsulosin is an antagonist of adrenergic activity through blocking the activity of alpha-1 adrenoreceptors. This property makes Tamsulosin useful to be used as a drug in combination therapy for the treatment of benign prostatic hyperplasia (BPH) and urinary symptoms associated with an enlarged prostate. Tamsulosin has been shown to have a significant effect on BPH symptoms and urinary flow rates, as well as improved quality of life.

Formula: C₂₀H₂₈N₂O₅S•HCl

Purity: Min. 99 Area-%

Color and Shape: Powder

Molecular weight: 444.97 g/mol

Ref: 3D-BT164440

(R)-Tamsulosin hydrochloride

CAS: 106463-17-6

Tamsulosin HCL is an antagonist of adrenergic activity through blocking the activity of alpha-1 adrenoreceptors. This property makes Tamsulosin HCL useful to be used as a drug in combination therapy for the treatment of benign prostatic hyperplasia (BPH) and urinary symptoms associated with an enlarged prostate. Tamsulosin has been shown to have a significant effect on BPH symptoms and urinary flow rates, as well as improved quality of life. The combination therapy group showed significant improvements in both of these areas when compared with the control group, which consisted of men who were given placebo pills instead of tamsulosin.

Formula: C₂₀H₂₈N₂O₅S•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 444.97 g/mol

Ref: 3D-FT27998

(R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide hydrochloride

CAS: 106463-17-6

Formula: C₂₀H₂₉ClN₂O₅S

Purity: 98%

Molecular weight: 444.97

Ref: 10-F361905

(R)-Tamsulosin-d5 Hydrochloride

Controlled Product

CAS: 106463-17-6

Applications (R)-Tamsulosin-d5 hydrochloride is deuterium labelled (R)-Tamsulosin hydrochloride, which is a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.
References Kawabe, K., et al.: J. Urol., 144, 908 (1990); Abrams, P., et al.: Br. J. Urol., 76, 325 (1995); Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004)

Formula: C₂₀D₅H₂₃N₂O₅S·ClH

Color and Shape: Neat

Molecular weight: 450.0

Ref: TR-T006349