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Tris(hydroxymethyl)aminomethane hydrochloride

CAS 1185-53-1: Tris(hydroxymethyl)aminomethane hydrochloride

Description:Tris(hydroxymethyl)aminomethane hydrochloride, commonly known as Tris hydrochloride, is a white crystalline powder that is highly soluble in water. It is a buffering agent widely used in biochemistry and molecular biology to maintain a stable pH in various biological and chemical reactions. The compound features three hydroxymethyl groups attached to an amino group, which contributes to its buffering capacity, particularly in the physiological pH range. Tris hydrochloride is often utilized in the preparation of buffers for electrophoresis, cell culture, and enzyme assays. Its pKa value is around 8.1, making it effective for buffering solutions near neutral pH. Additionally, Tris hydrochloride is relatively non-toxic and has low reactivity, which makes it suitable for use in sensitive biological applications. However, it is important to note that Tris can interfere with certain assays, particularly those involving phenolic compounds. Proper handling and storage conditions should be observed to maintain its stability and effectiveness.

Formula:C4H11NO3·ClH

InChI:InChI=1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

InChI key:InChIKey=QKNYBSVHEMOAJP-UHFFFAOYSA-N

SMILES:Cl.OCC(N)(CO)CO

  • Synonyms:
  • 1,3-Propanediol, 2-Amino-2-(Hydroxymethyl)-, Chloride
  • 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1:1)
  • 1,3-Propanediol,2-amino-2-(hydroxymethyl)-,hydrochloride
  • 2-Amino-2-(Hidroximetil)Propano-1,3-Diol, Clorhidrato
  • 2-Amino-2-(Hydroxymethyl)-1,3-Propanediol, Hydrochloride
  • 2-Amino-2-(Hydroxymethyl)Propane-1,3-Diol Hydrochloride
  • 2-Amino-2-(Hydroxymethyl)Propane-1,3-Diol Hydrochloride (1:1)
  • 2-Amino-2-(hydroxymethyl)propan-1,3-diolhydrochlorid
  • 2-Amino-2-(hydroxymethyl)propane-1,3-diol, chlorhydrate
  • 3-Propanediol,2-Amino-2-(Hydroxymethyl)-Hydrochloride
  • See more synonyms
  • Mole-Ready-Tris
  • Propane-1,3-Diol, 2-Amino-2-(Hydroxymethyl)-, Hydrochloride
  • Spectris(R) Hydrochloride
  • Spectris(Tm) Hydrochloride
  • T 6666
  • TRIZMA Hydrochloride
  • Tri(hydroxymethyl)aminomethane hydrochloride
  • Tris Hydrochloride
  • Tris chloride
  • Tris(hydroxymethyl)amino methane Hydrochloride
  • Tris(hydroxymethyl)aminoethane hydrochloride
  • Tris(hydroxymethyl)aminomethane hydrochloride
  • Tris-hydrochloric acid
  • Tris.HCl
  • Tris・Hcl
  • Trizmahydrochloride(Trishydrochloride)
  • Tromethamine hydrochloride
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BrandProduct dataPurityPrice rangeEstimated delivery
Cygnus logo
Anti-BSA:HRP Conjugate
REF: 5M-F033-12
CAS:
- - -819.00 €Tue 22 Apr 25
Cygnus logo
Anti-MRC5:HRP Conjugate
REF: 5M-F301-12
CAS:
- - -1,065.00 €Tue 22 Apr 25
Cygnus logo
Anti-HSA:Biotinylated Conjugate
REF: 5M-F056-12
CAS:
- - -900.00 €Tue 22 Apr 25
Cygnus logo
Anti-MDCK:HRP Conjugate
REF: 5M-F801-12
CAS:
- - -1,065.00 €Tue 22 Apr 25
Cygnus logo
Anti-CHO:HRP Conjugate, 3G
REF: 5M-F551-1-12
CAS:
- - -981.00 €Tue 22 Apr 25
Cygnus logo
Anti-Insulin:Alkaline Phosphatase Conjugate
REF: 5M-F041-12
CAS:
- - -900.00 €Tue 22 Apr 25
Cygnus logo
Anti-HeLa:HRP Conjugate
REF: 5M-F811-12
CAS:
- - -1,065.00 €Tue 22 Apr 25
Cygnus logo
Anti-Bovine IgG:HRP Conjugate
REF: 5M-F071-12
CAS:
- - -981.00 €Tue 22 Apr 25
Cygnus logo
CAP® Cell HCP Standards Set, A-H
REF: 5M-F823
CAS:
- - -887.00 €Tue 22 Apr 25
Cygnus logo
Anti-BHK:HRP Conjugate
REF: 5M-F511-12
CAS:
- - -1,259.00 €Tue 22 Apr 25
Cygnus logo
Bovine IgG Antigen Concentrate
REF: 5M-F073G
CAS:
- - -406.00 €Tue 22 Apr 25
Cygnus logo
Anti-Bovine Transferrin:HRP Conjugate
REF: 5M-F123-12
CAS:
- - -900.00 €Tue 22 Apr 25
Cygnus logo
BSA Antigen Concentrate
REF: 5M-F031G
CAS:
- - -782.00 €Tue 22 Apr 25
Apollo Scientific logo
Tris hydrochloride
REF: 54-BIT1513
CAS: 1185-53-1
>99.5%38.00 €~241.00 €Tue 22 Apr 25
Cygnus logo
Anti-P. fluorescens:HRP Conjugate
REF: 5M-F451-12
CAS:
- - -1,065.00 €Tue 22 Apr 25
Glentham logo
TRIS hydrochloride, 1M solution (pH 8.5)
REF: 7W-GB7844
CAS: 1185-53-1
- - -To inquireTue 22 Apr 25
Cygnus logo
Anti-BHK: HRP Conjugate Concentrate
REF: 5M-F511C
CAS:
- - -To inquireTue 22 Apr 25
Glentham logo
TRIS hydrochloride
REF: 7W-GB4431
CAS: 1185-53-1
(Titration) 99.0 - 101.0 % (dried basis)33.00 €~457.00 €Tue 22 Apr 25
Cygnus logo
BSA Sample Diluent
REF: 5M-F031A
CAS:
- - -241.00 €~1,118.00 €Tue 22 Apr 25
Apollo Scientific logo
Tris Hydrochloride for molecular biology
REF: 54-BIA3452
CAS: 1185-53-1
- - -32.00 €~1,421.00 €Tue 22 Apr 25
discount label

Anti-BSA:HRP Conjugate


Ref: 5M-F033-12

12ml819.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Ref: 5M-F301-12

12ml1,065.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Anti-HSA:Biotinylated Conjugate


Ref: 5M-F056-12

12ml900.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Ref: 5M-F801-12

12ml1,065.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Anti-CHO:HRP Conjugate, 3G


Ref: 5M-F551-1-12

12ml981.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Anti-Insulin:Alkaline Phosphatase Conjugate


Ref: 5M-F041-12

12ml900.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Anti-HeLa:HRP Conjugate


Ref: 5M-F811-12

12ml1,065.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Anti-Bovine IgG:HRP Conjugate


Ref: 5M-F071-12

12ml981.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

CAP® Cell HCP Standards Set, A-H


Ref: 5M-F823

1ml887.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Ref: 5M-F511-12

12ml1,259.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Bovine IgG Antigen Concentrate


Ref: 5M-F073G

200µl406.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Anti-Bovine Transferrin:HRP Conjugate


Ref: 5M-F123-12

12ml900.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

BSA Antigen Concentrate


Ref: 5M-F031G

1ml782.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Tris hydrochloride

CAS:1185-53-1

Ref: 54-BIT1513

1kg102.00 €
5kg241.00 €
100g38.00 €
250g52.00 €
500g82.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Ref: 5M-F451-12

12ml1,065.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

TRIS hydrochloride, 1M solution (pH 8.5)

CAS:1185-53-1

Ref: 7W-GB7844

Undefined sizeTo inquire
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Anti-BHK: HRP Conjugate Concentrate


Ref: 5M-F511C

1mgTo inquire
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

TRIS hydrochloride

CAS:1185-53-1

Ref: 7W-GB4431

1kg128.00 €
5kg457.00 €
100g33.00 €
250g46.00 €
500g74.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

BSA Sample Diluent


Ref: 5M-F031A

100ml241.00 €
500ml800.00 €
1000ml1,118.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Tris Hydrochloride for molecular biology

CAS:1185-53-1

Ref: 54-BIA3452

100g32.00 €
25kg1,421.00 €
500g53.00 €
2.5kg181.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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