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Tris(hydroxymethyl)aminomethane hydrochloride

CAS 1185-53-1: Tris(hydroxymethyl)aminomethane hydrochloride

Description:Tris(hydroxymethyl)aminomethane hydrochloride, commonly known as Tris hydrochloride, is a white crystalline powder that is highly soluble in water. It is a buffering agent widely used in biochemistry and molecular biology to maintain a stable pH in various biological and chemical reactions. The compound features three hydroxymethyl groups attached to an amino group, which contributes to its buffering capacity, particularly in the physiological pH range. Tris hydrochloride is often utilized in the preparation of buffers for electrophoresis, cell culture, and enzyme assays. Its pKa value is around 8.1, making it effective for buffering solutions near neutral pH. Additionally, Tris hydrochloride is relatively non-toxic and has low reactivity, which makes it suitable for use in sensitive biological applications. However, it is important to note that Tris can interfere with certain assays, particularly those involving phenolic compounds. Proper handling and storage conditions should be observed to maintain its stability and effectiveness.

Formula:C4H11NO3·ClH

InChI:InChI=1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

InChI key:InChIKey=QKNYBSVHEMOAJP-UHFFFAOYSA-N

SMILES:Cl.OCC(N)(CO)CO

  • Synonyms:
  • 1,3-Propanediol, 2-Amino-2-(Hydroxymethyl)-, Chloride
  • 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1:1)
  • 1,3-Propanediol,2-amino-2-(hydroxymethyl)-,hydrochloride
  • 2-Amino-2-(Hidroximetil)Propano-1,3-Diol, Clorhidrato
  • 2-Amino-2-(Hydroxymethyl)-1,3-Propanediol, Hydrochloride
  • 2-Amino-2-(Hydroxymethyl)Propane-1,3-Diol Hydrochloride
  • 2-Amino-2-(Hydroxymethyl)Propane-1,3-Diol Hydrochloride (1:1)
  • 2-Amino-2-(hydroxymethyl)propan-1,3-diolhydrochlorid
  • 2-Amino-2-(hydroxymethyl)propane-1,3-diol, chlorhydrate
  • 3-Propanediol,2-Amino-2-(Hydroxymethyl)-Hydrochloride
  • See more synonyms
  • Mole-Ready-Tris
  • Propane-1,3-Diol, 2-Amino-2-(Hydroxymethyl)-, Hydrochloride
  • Spectris(R) Hydrochloride
  • Spectris(Tm) Hydrochloride
  • T 6666
  • TRIZMA Hydrochloride
  • Tri(hydroxymethyl)aminomethane hydrochloride
  • Tris Hydrochloride
  • Tris chloride
  • Tris(hydroxymethyl)amino methane Hydrochloride
  • Tris(hydroxymethyl)aminoethane hydrochloride
  • Tris(hydroxymethyl)aminomethane hydrochloride
  • Tris-hydrochloric acid
  • Tris.HCl
  • Tris・Hcl
  • Trizmahydrochloride(Trishydrochloride)
  • Tromethamine hydrochloride
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BrandProduct dataPurityPrice rangeEstimated delivery
Cygnus logo
Block/Wash 20x Concentrate
REF: 5M-F062
CAS:
- - -235.00 €~860.00 €Tue 22 Apr 25
Cygnus logo
Anti-CAP® Cell: HRP Conjugate
REF: 5M-F821-12
CAS:
- - -981.00 €Tue 22 Apr 25
Cygnus logo
BSA Standards Set, A-E
REF: 5M-F031
CAS:
- - -711.00 €Tue 22 Apr 25
Acros logo
Tris(hydroxymethyl)aminomethane hydrochloride, 99+%, extra pure
REF: AC-22803
CAS: 1185-53-1
99+%To inquireTue 22 Apr 25
TRC logo
Tris Hydrochloride
REF: TR-T887988
CAS: 1185-53-1
- - -114.00 €~181.00 €Tue 29 Apr 25
Fluorochem logo
Tris(hydroxymethyl)aminomethane hydrochloride
REF: 10-M02622
CAS: 1185-53-1
>98%To inquireTue 29 Apr 25
Biosynth logo
TRIS hydrochloride
REF: 3D-FT45361
CAS: 1185-53-1
- - -143.00 €~4,521.00 €Mon 12 May 25
Sisco Research Laboratories logo
Tris Hydrochloride (Tris HCl) extrapure AR, 99%
REF: SR-99438
CAS: 1185-53-1
min. 99.0%26.00 €~590.00 €Mon 19 May 25
Sisco Research Laboratories logo
Tris Hydrochloride (Tris HCl) for molecular biology, 99%
REF: SR-89781
CAS: 1185-53-1
mim. 99.0%32.00 €~119.00 €Mon 19 May 25
Targetmol logo
Trometamol hydrochloride
REF: TM-T23478
CAS: 1185-53-1
99.39%34.00 €~47.00 €Tue 10 Jun 25
Cygnus logo
Anti-P. pastoris:HRP Conjugate
REF: 5M-F147-50
CAS:
- - -- - -Discontinued product
Cygnus logo
Anti-SP2/0:HRP Conjugate
REF: 5M-F187
CAS:
- - -- - -Discontinued product
Cygnus logo
Anti-S. cerevisiae:Biotinylated Conjugate
REF: 5M-F134-50
CAS:
- - -- - -Discontinued product
Cygnus logo
Anti-PER.C6®:HRP Conjugate
REF: 5M-F531-12
CAS:
- - -- - -Discontinued product
Cygnus logo
Anti-CHO:HRP Conjugate Concentrate, 3G
REF: 5M-F551C
CAS:
- - -- - -Discontinued product
Cygnus logo
Anti-NS/0:HRP Conjugate
REF: 5M-F226-50
CAS:
- - -- - -Discontinued product
Cygnus logo
Anti-SF9:HRP Conjugate
REF: 5M-F841-12
CAS:
- - -- - -Discontinued product
Cygnus logo
Anti-CHO:HRP Conjugate, 3G
REF: 5M-F551-12
CAS:
- - -- - -Discontinued product
Cygnus logo
Anti-Vero Cell:HRP Conjugate
REF: 5M-F501-12
CAS:
- - -- - -Discontinued product
Cygnus logo
Anti-A549:HRP Conjugate
REF: 5M-F236-50
CAS:
- - -- - -Discontinued product
discount label

Ref: 5M-F062

50ml235.00 €
100ml420.00 €
1000ml860.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Ref: 5M-F821-12

12ml981.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

BSA Standards Set, A-E


Ref: 5M-F031

1ml711.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Tris(hydroxymethyl)aminomethane hydrochloride, 99+%, extra pure

CAS:1185-53-1

Ref: AC-22803

1kgTo inquire
5kgTo inquire
100gTo inquire
250gTo inquire
Estimated delivery in United States, on Tuesday 22 Apr 2025
discount label

Tris Hydrochloride

Controlled Product
CAS:1185-53-1

Ref: TR-T887988

50g114.00 €
100g181.00 €
Estimated delivery in United States, on Tuesday 29 Apr 2025
discount label

Tris(hydroxymethyl)aminomethane hydrochloride

CAS:1185-53-1

Ref: 10-M02622

1kg102.00 €
25g24.00 €
5kgTo inquire
100g28.00 €
250g51.00 €
500g58.00 €
Estimated delivery in United States, on Tuesday 29 Apr 2025
discount label

TRIS hydrochloride

CAS:1185-53-1

Ref: 3D-FT45361

1kg293.00 €
2kg469.00 €
5kg1,002.00 €
10kg1,912.00 €
25kg4,521.00 €
Estimated delivery in United States, on Monday 12 May 2025
discount label

Tris Hydrochloride (Tris HCl) extrapure AR, 99%

CAS:1185-53-1

Ref: SR-99438

5kg590.00 €
100g26.00 €
500g64.00 €
Estimated delivery in United States, on Monday 19 May 2025
discount label

Tris Hydrochloride (Tris HCl) for molecular biology, 99%

CAS:1185-53-1

Ref: SR-89781

1kg119.00 €
100g32.00 €
500g73.00 €
Estimated delivery in United States, on Monday 19 May 2025
discount label

Trometamol hydrochloride

CAS:1185-53-1

Ref: TM-T23478

500mg34.00 €
1mL*10mM (DMSO)47.00 €
Estimated delivery in United States, on Tuesday 10 Jun 2025
discount label
Discontinued product
discount label

Anti-SP2/0:HRP Conjugate


Discontinued product
discount label

Anti-CHO:HRP Conjugate Concentrate, 3G


Discontinued product
discount label

Anti-NS/0:HRP Conjugate


Discontinued product
discount label

Anti-SF9:HRP Conjugate


Discontinued product
discount label

Anti-CHO:HRP Conjugate, 3G


Discontinued product
discount label

Anti-A549:HRP Conjugate


Discontinued product
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