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CAS 123997-26-2

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Eprinomectin

Description:
Eprinomectin is a macrocyclic lactone compound primarily used as an antiparasitic agent in veterinary medicine. It is derived from the fermentation of the soil bacterium Streptomyces avermitilis and is known for its efficacy against a broad spectrum of internal and external parasites, including nematodes and arthropods. Eprinomectin works by binding to glutamate-gated chloride channels and other ligand-gated ion channels in the nervous system of parasites, leading to paralysis and death. This compound is characterized by its high lipophilicity, which allows for effective absorption and distribution in animal tissues. Eprinomectin is unique among its class as it is approved for use in lactating dairy cattle, as it has a low residue profile, making it safe for milk production. Its formulation is typically available as a pour-on solution or injectable, providing flexibility in administration. Safety profiles indicate that it has a low toxicity to mammals, including humans, when used as directed. Overall, eprinomectin is a valuable tool in managing parasitic infections in livestock.
Formula:Unspecified
InChI:InChI=1/C50H75NO14/c1-12-26(2)45-29(5)18-19-49(65-45)24-36-21-35(64-49)17-16-28(4)44(27(3)14-13-15-34-25-58-47-43(53)30(6)20-37(48(54)61-36)50(34,47)55)62-41-23-39(57-11)46(32(8)60-41)63-40-22-38(56-10)42(31(7)59-40)51-33(9)52/h13-16,18-20,26-27,29,31-32,35-47,53,55H,12,17,21-25H2,1-11H3,(H,51,52)/b14-13+,28-16+,34-15+/t26-,27-,29-,31-,32-,35+,36-,37-,38-,39-,40-,41-,42+,43+,44-,45+,46-,47+,49+,50+/m0/s1
Synonyms:
  • (2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-(1-methylethyl)-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 4-O-[4-(acetylamino)-2,4,6-trideoxy-3-O-methyl-α-L-xylo-hexopyranosyl]-2,6-dideoxy-3-O-methyl-α-L-lyxo-hexopyranoside
  • (4''R)-4''-(Acetylamino)-4''-Deoxy-Avermectin B1
  • (4''R)-4''-(Acetylamino)-4''-Deoxy-Avermectin B1Solution
  • Avermectin B1, 4-(acetylamino)-4-deoxy-, (4R)-
  • Avermectin B<sub>1</sub>, 4′′-(acetylamino)-4′′-deoxy-, (4′′R)-
  • Emamectin B1 Benzoate
  • Eprinex
  • Eprinomectin Vetranal
  • Eprinomectin, 100 ng/�l in Acetonitril , Vetranal
  • EprinomectinB1
  • See more synonyms
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