CAS 133550-30-8: (2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide

Description: (2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide, with the CAS number 133550-30-8, is an organic compound characterized by its unique structural features. It contains a cyano group (-CN), which contributes to its reactivity and potential applications in organic synthesis. The presence of a propenamide functional group indicates that it can participate in various chemical reactions, including nucleophilic additions and polymerization. The compound also features a 3,4-dihydroxyphenyl moiety, which may impart antioxidant properties and influence its biological activity. The phenylmethyl group suggests that it may exhibit lipophilic characteristics, potentially affecting its solubility and interaction with biological membranes. Overall, this compound's structural complexity and functional groups suggest it may have applications in pharmaceuticals or as a biochemical probe, although specific biological activities would require further investigation. Its synthesis and reactivity can be explored in the context of medicinal chemistry and material science.

Formula: C₁₇H₁₄N₂O₃

InChI: InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+

InChI key: InChIKey=TUCIOBMMDDOEMM-RIYZIHGNSA-N

SMILES: N#CC(=CC1=CC=C(O)C(O)=C1)C(=O)NCC=2C=CC=CC2

Synonyms:

• (2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide
• (2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
• (E)-2-Cyano-3-(3,4-Dihydrophenyl)-N-(Phenylmethyl)-2-Propenamide
• 2-Cyano-3-[3,4-Dihydroxyphenyl]-N-[Phenylmethyl]-2-Propenamide
• 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-, (2E)-
• 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-, (E)-
• A-Cyano-(3,4-Dihydroxy)-N-Benzylcinnamamide
• A-Cyano-(3,4-Dihydroxy)-N-Benzylcinnamide
• Ag490
• N-Benzyl-3,4-Dihydroxy-Alpha-Cyanocinnamide
• Tyrphostin AG-490
• Tyrphostin B42
• AG-490
• AG 490

(E)-N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide；AG 490

CAS: 133550-30-8

• Formula: C₁₇H₁₄N₂O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 294.3047

Tyrphostin AG 490

CAS: 133550-30-8

• Formula: C₁₇H₁₄N₂O₃
• Molecular weight: 294.30

Tyrphostin AG 490

CAS: 133550-30-8

• Formula: C₁₇H₁₄N₂O₃
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 294.31

AG490

CAS: 133550-30-8

AG490 inhibits EGFR (0.1 μM IC50), 135x >selective than ErbB2, blocks JAK2, spares Lyn, Lck, …

• Formula: C₁₇H₁₄N₂O₃
• Purity: 98.6% - 99.7%
• Color and Shape: Yellow Solid
• Molecular weight: 294.3

N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide

CAS: 133550-30-8

• Purity: 99.0%
• Molecular weight: 294.30999755859375

Tyrphostin B42

CAS: 133550-30-8

• Formula: C₁₇H₁₄N₂O₃
• Color and Shape: Neat
• Molecular weight: 294.305

(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide

CAS: 133550-30-8

(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide (TPCA) is a tyrphostin and inhibitor of protein kinases. TPCA targets the proteins that …

• Formula: C₁₇H₁₄N₂O₃
• Purity: Min. 95%
• Molecular weight: 294.3 g/mol