CAS 1401-69-0

Tylosin

Description:

Tylosin is a macrolide antibiotic primarily used in veterinary medicine, particularly for livestock and poultry, to treat bacterial infections and promote growth. It is derived from the bacterium *Streptomyces fradiae* and exhibits a broad spectrum of activity against Gram-positive bacteria and some Gram-negative bacteria. Tylosin functions by inhibiting protein synthesis in bacteria, thereby preventing their growth and reproduction. The substance is typically administered in the form of its tartrate salt, which enhances its solubility. Tylosin is known for its relatively low toxicity in animals, but its use is regulated in food-producing animals to prevent antibiotic residues in meat products. Additionally, it has been studied for its potential applications in aquaculture and as a feed additive. Its chemical structure features a large lactone ring, characteristic of macrolides, which contributes to its antibacterial properties. As with many antibiotics, the emergence of resistance is a concern, necessitating careful management of its use in agricultural practices.

Formula: C₄₆H₇₇NO₁₇

InChI: InChI=1S/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/b15-14+,23-18+/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-/m1/s1

InChI key: InChIKey=WBPYTXDJUQJLPQ-VMXQISHHSA-N

SMILES: O([C@H]1[C@H](N(C)C)[C@@H](O)[C@H](O[C@H]2[C@@H](CC=O)C[C@@H](C)C(=O)/C=C/C(/C)=C/[C@H](CO[C@H]3[C@H](OC)[C@H](OC)[C@H](O)[C@@H](C)O3)[C@@H](CC)OC(=O)C[C@@H](O)[C@@H]2C)O[C@@H]1C)[C@H]4C[C@@](C)(O)[C@@H](O)[C@H](C)O4

Synonyms:

• Fradizine
• Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 15-[[(6-deoxy-2,3-di-O-methyl-β-<span class="text-smallcaps">D</smallcap>-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-<smallcap>L</smallcap>-ribo-hexopyranosyl)-3-(dimethylamino)-β-<smallcap>D</span>-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxo-, [4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15R*,16R*)]-
• Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 15-[[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxo-, [4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15R*,16R*)]-
• Oxacyclohexadecane, tylosin deriv.
• Tilan
• Tilosina
• Tylocine
• Tylosin A
• Tylosin base
• Tylosine
• Vubityl 200
• [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-(dimethylamino)-beta-D-glucopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside
• [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-galactopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-D-allopyranoside
• [(2R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-(dimethylamino)-beta-D-glucopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside
• [(2R,4E,6E,9R,11R,12S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-D-allopyranoside
• [4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15R*,16R*)]-15-[[(6-Deoxy-2,3-di-O-methyl-β-<span class="text-smallcaps">D</smallcap>-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-<smallcap>L</smallcap>-ribo-hexopyranosyl)-3-(dimethylamino)-β-<smallcap>D</span>-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxooxacyclohexadeca-11,13-diene-7-acetaldehyde
• [4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15R*,16R*)]-15-[[(6-Deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxooxacyclohexadeca-11,13-diene-7-acetaldehyde

Tylosin

CAS: 1401-69-0

Tylosin

Color and Shape: Off-White

Ref: 47-349

TYLOSIN CRS

CAS: 1401-69-0

TYLOSIN CRS

Formula: C₄₆H₇₇NO₁₇

Molecular weight: 916.1001

Ref: 41-T2880000

FIRST INTERNATIONAL STANDARD FOR TYLOSIN

CAS: 1401-69-0

FIRST INTERNATIONAL STANDARD FOR TYLOSIN

Formula: C₄₆H₇₇NO₁₇

Molecular weight: 916.1001

Ref: 41-ISA_TYN

Tylosin

CAS: 1401-69-0

Antibiotics nesoi

Formula: C₄₆H₇₇NO₁₇

Color and Shape: White Off-White Yellow Powder

Molecular weight: 916.1 g/mol

Ref: 45-1703805

Tylosin

CAS: 1401-69-0

Formula: C₄₆H₇₇NO₁₇

Purity: 80%

Color and Shape: Solid

Molecular weight: 916.1001

Ref: IN-DA00HVQN

Tylosin

CAS: 1401-69-0

Tylosin

Purity: mixture

Molecular weight: 916.1g/mol

Ref: 54-BUP14011

Tylosin

CAS: 1401-69-0

Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae.

Formula: C₄₆H₇₇NO₁₇

Purity: mixture - mixture

Color and Shape: Coa

Molecular weight: 916.10

Ref: TM-T1003

Tylosin

CAS: 1401-69-0

Tylosin

Purity: 93%

Molecular weight: 916.1g/mol

Ref: 54-OR1029875

Tylosin

CAS: 1401-69-0

Formula: C₄₆H₇₇NO₁₇

Purity: ≥ 900IU/mg

Color and Shape: White, almost white or pale yellow powder

Molecular weight: 916.10

Ref: 7W-GA0812

Tylosin-d3

CAS: 1401-69-0

Formula: C₄₆H₇₄D₃NO₁₇

Molecular weight: 919.14

Ref: 4Z-T-175002

Tylosin

CAS: 1401-69-0, 8026-48-0

Formula: C₄₆H₇₇NO₁₇

Color and Shape: White To Off-White Solid

Molecular weight: 916.12

Ref: 4Z-T-175001

Tylosin A 100 µg/mL in Acetonitrile

CAS: 1401-69-0

Formula: C₄₆H₇₇NO₁₇

Color and Shape: Single Solution

Molecular weight: 916.10

Ref: 04-A17895615AL-100

GB 31660.1-2019 Macrolide Antibiotics Mixture 167 100 µg/mL in Methanol

Controlled Product

CAS: 114-07-8, 1401-69-0, 16846-24-5, 2751-09-9, 69-23-8, 8025-81-8, 81103-11-9, 83905-01-5, 93952-07-9

Color and Shape: Mixture

Ref: 04-A50000167ME

Tylosin-d3 (100 Mug/mL in Methanol)

CAS: 1401-69-0

Formula: C₄₆H₇₄D₃NO₁₇

Color and Shape: Colourless

Molecular weight: 916.10

Ref: TR-KIT9112

Tylosin-d3

Controlled Product

CAS: 1401-69-0

Applications Labelled Tylosin (T947650). Tylosin is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hamill, et al.: Antibiot. Chemother., 11, 328 (1961), Corcoran, J.W., et al.: J. Antibiot., 30, 1012 (1977), Seno, E.T., et al.: Antimicrob. Agents. Chemother., 11, 455 (1977),

Formula: C₄₆H₇₄D₃NO₁₇

Color and Shape: Neat

Molecular weight: 916.10

Ref: TR-T947652

Tylosin

CAS: 1401-69-0

Stability Light Sensitive
Applications Tylosin is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial. This compound is a contaminant of emerging concern (CECs).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hamill, et al.: Antibiot. Chemother., 11, 328 (1961), Corcoran, J.W., et al.: J. Antibiot., 30, 1012 (1977), Seno, E.T., et al.: Antimicrob. Agents. Chemother., 11, 455 (1977),

Formula: C₄₆H₇₇NO₁₇

Color and Shape: Off-White

Molecular weight: 916.10

Ref: TR-T947650

Tylosin

CAS: 1401-69-0

Purity: 93%+;RG

Molecular weight: 916.1119995

Ref: 10-F951543