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CAS 8025-81-8

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Spiramycin

Description:
Spiramycin is a macrolide antibiotic produced by the fermentation of the bacterium Streptomyces ambofaciens. It is primarily used in veterinary medicine and occasionally in human medicine for its antibacterial properties, particularly against Gram-positive bacteria and some protozoa. Spiramycin exhibits a broad spectrum of activity, making it effective in treating various infections, including respiratory and dental infections. The compound is characterized by its large lactone ring structure, which is typical of macrolides, and it contains multiple sugar moieties that contribute to its solubility and bioactivity. Spiramycin is known for its ability to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and reproduction of bacteria. It is generally well-tolerated, but like other antibiotics, it may cause side effects such as gastrointestinal disturbances. Due to its unique properties, Spiramycin is often used in cases where other antibiotics may be less effective or when a specific bacterial resistance is present.
Formula:Unspecified
InChI:InChI=1/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1
Synonyms:
  • Antibiotic 799
  • Espiramicin
  • Espiramicina
  • Foromacidin
  • Il 5902
  • Nsc 55926
  • Provamycin
  • Rovamicina
  • Rovamycin
  • Rovamycine
  • See more synonyms
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