CAS 83905-01-5
:Azithromycin
Description:
Azithromycin is a macrolide antibiotic characterized by its broad-spectrum activity against various bacterial infections. It is derived from erythromycin and is known for its unique structure, which includes a large lactone ring and several sugar moieties. Azithromycin is typically administered orally and is notable for its extended half-life, allowing for once-daily dosing and shorter treatment courses compared to other antibiotics. It works by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit, effectively preventing the growth of bacteria. Azithromycin is effective against a range of pathogens, including those responsible for respiratory infections, skin infections, and sexually transmitted diseases. It is generally well-tolerated, with common side effects including gastrointestinal disturbances. Additionally, it has anti-inflammatory properties, which can be beneficial in treating certain conditions beyond bacterial infections. Its pharmacokinetics, including good tissue penetration and accumulation in cells, contribute to its efficacy in treating infections. Azithromycin is also included in treatment regimens for certain atypical infections and is often used in combination therapies.
Formula:C38H72N2O12
InChI:InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
InChI key:InChIKey=MQTOSJVFKKJCRP-BICOPXKESA-N
SMILES:O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3
Synonyms:- (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
- (2R,3S,4R,5S,6R,8R,11S,12R,13R,14S)-5-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-ethyl-6,12,13-trihydroxy-3-[(2S,4R,5S,6R)-5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-2,4,6,8,10,11,13-heptamethyl-15-oxa-10-azacyclopentadecan-1-one
- 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
- 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-
- 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
- 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-
- 1-Oxa-6-azacyclopentadecan-15-one,13-((2,6-dideoxy-3-C-methyl-1-3-O-methyl-alpha-L-ribo-hexopyranosyl)-oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)
- 11-(4-Dimethylamino-3-Hydroxy-6-Methyl-Oxan-2-Yl)Oxy-2-Ethyl-3,4,10-Tr
- 9-Deoxo-9-methyl-9a-aza-9-homoerythromycin A
- 9-Deoxo-9a-methyl-9a-aza-9a-homoetrythromycin A
- 9-deoxo-9a-methyl-9a-aza-homoerythromycin A
- Aruzilina
- Arzomicin
- Auricin
- Auricin (polyketide antibiotic)
- AzaSite
- Azadose
- Azatril
- Azee
- Azenil
- Azimin
- Aziromycin
- Azisara
- Azithral
- Azithrocin
- Azithromycin A
- Azithromycine
- Azitrocin
- Azitromax
- Aziwin
- Aziwok
- Azomycin
- Azomycin (macrolide)
- Aztrin
- Cp 62993
- Durasite
- Hemomycin
- Macromycin
- Macrozit
- N-methyl-11-aza-10-deoxo-10-dihydroerythromycin A
- Sanhe
- Setron
- Shimen
- Sumamed
- Sumazid
- Tobil
- Tridosil
- Tromix
- Trozocina
- Ultreon
- Xithron
- Xithrone
- Xz 405
- Xz 450
- Zeto
- Zi-Factor
- Zifin
- Zistic
- Zithromac
- Zithromax
- Zithromax IV
- Zitrim
- Zitrocin
- Zitromax
- Zythromax
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Azithromycin
CAS:AzithromycinFormula:C38H72N2O12Purity:By hplc: 97.7% by area (Typical Value in Batch COA)Color and Shape:White Solid-PowderMolecular weight:748.98448GB 31660.1-2019 Macrolide Antibiotics Mixture 167 100 µg/mL in Methanol
CAS:Controlled ProductColor and Shape:MixtureAzithromycin-d5
CAS:Controlled ProductApplications Azithromycin-d5, is the labeled analogue Azithromycin (A927000), a semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.
References Langtry, H.D., et al.: Drugs, 56, 273 (1998),Formula:C38H67D5N2O12Color and Shape:NeatMolecular weight:754.02Azithromycin
CAS:Applications Azithromycin is an azalide macrolide antibiotic.
References Hunter, R., et al.: J. Vet. Pharmacol. Ther., 26, 117 (2003);Formula:C38H72N2O12Color and Shape:NeatMolecular weight:748.98Azithromycin-13CD3
CAS:Controlled ProductApplications Labelled Azithromycin, a semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.
References Langtry, H.D., et al.: Drugs, 56, 273 (1998),Formula:C3713CH69D3N2O12Color and Shape:NeatMolecular weight:753Azithromycin
CAS:Azithromycin (CP 62993) is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes. High-Quality, Low-Cost!Formula:C38H72N2O12Purity:99.9% - 99.97%Color and Shape:White To Off-White Solid CrystallineMolecular weight:748.98Azithromycin
CAS:A broad-spectrum antibiotic of macrolide class which targets 50S ribosome subunit and inhibits protein synthesis. Azithromycin is a semi-synthetic acid-stable derivative of erythromycin. In vitro, azithromycin is more efficient than erythromycin in some Gram-negative organisms such as Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Neisseria gonorrhoeae and Borrelia burgdorferi.Formula:C38H72N2O12Purity:945.0 To 1030.0 U/MgColor and Shape:White PowderMolecular weight:748.98 g/molAzithromycin-d5 (major) in Methanol
CAS:MethanolFormula:C38H72N2O12Color and Shape:SolidMolecular weight:749.0Azithromycin Solution Reference Material in Methanol
CAS:Formula:C38H72N2O12Color and Shape:SolidMolecular weight:749.0
