CAS 154361-50-9: Capecitabine

Description:Capecitabine is an oral chemotherapeutic agent primarily used in the treatment of various cancers, including colorectal and breast cancer. It is a prodrug, meaning it is metabolized in the body to its active form, 5-fluorouracil (5-FU), which interferes with DNA synthesis and inhibits tumor growth. Capecitabine is characterized by its ability to selectively target cancer cells, which enhances its efficacy while minimizing damage to normal tissues. The compound is typically administered in a tablet form and is known for its favorable pharmacokinetic profile, allowing for convenient dosing schedules. Its mechanism of action involves the inhibition of thymidylate synthase, an enzyme critical for DNA replication. Capecitabine is generally well-tolerated, but it can cause side effects such as gastrointestinal disturbances, hand-foot syndrome, and myelosuppression. The drug's effectiveness can be influenced by genetic factors, particularly variations in enzymes involved in its metabolism, making pharmacogenomic testing relevant in some cases. Overall, capecitabine represents a significant advancement in targeted cancer therapy.

Formula:C₁₅H₂₂FN₃O₆

InChI:InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1

InChI key:InChIKey=GAGWJHPBXLXJQN-UORFTKCHSA-N

SMILES:O=C(OCCCCC)NC1=NC(=O)N(C=C1F)C2OC(C)C(O)C2O

Synonyms:
1-(5-deoxypentofuranosyl)-5-fluoro-4-{[(pentyloxy)carbonyl]amino}pyrimidin-2(1H)-one
5-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine
5′-Deoxy-5-fluoro-N4-(pentyloxycarbonyl)cytidine
Capacetrine
Capecitabine Accord
Capecitabine Medac
Capecitabine SUN
Capecitabine Teva
Capecitibine
Capecytabine
See more synonyms
Capiibine
Captabin
Carbamic acid, [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]-, pentyl ester
Cytidine, 5′-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-
Ecansya
N4-[(pentyloxy)carbonyl]-5'-deoxy-5-fluorocytidine
N4-Pentyloxycarbonyl-5′-deoxy-5-fluorocytidine
Pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate
R-340
Ro 09-1978/000
Ro-09-1978
Xeloda
Xeltabin
Carbamic acid, [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]-, pentyl ester
Capecitabine

Found 18 products.

Product data	Purity	Price range	Estimated delivery
Capecitabine CRS REF: 41-Y0001642CAS: 154361-50-9	- - -	115.00 €	Mon 14 Apr 25
Capecitabine REF: 47-1229CAS: 154361-50-9	99.9%	242.00 €	Mon 14 Apr 25
Capecitabine impurity B CRS REF: 41-Y0001644CAS: 154361-50-9	- - -	115.00 €	Mon 14 Apr 25
Capecitabine REF: 45-1090706CAS: 154361-50-9	- - -	447.00 €	Tue 15 Apr 25
5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine REF: IN-DA00389LCAS: 154361-50-9	98%	27.00 €~560.00 €	Wed 16 Apr 25
Capecitabine REF: TM-T1408CAS: 154361-50-9	100% - 99.89%	50.00 €~160.00 €	Wed 16 Apr 25
Capecitabine REF: 54-BUP18473CAS: 154361-50-9	99.52%	79.00 €~250.00 €	Thu 17 Apr 25
Capecitabine REF: 4Z-C-352CAS: 154361-50-9	- - -	To inquire	Thu 17 Apr 25
Capecitabine REF: 7W-GP6220CAS: 154361-50-9	98.0 - 102.0 % (dried basis)	89.00 €	Thu 17 Apr 25
Capecitabine, EP grade REF: 7W-GP3241CAS: 154361-50-9	98.0 - 102.0 % (anhydrous substance)	To inquire	Thu 17 Apr 25
Capecitabine REF: 54-PC109245CAS: 154361-50-9	- - -	32.00 €~2,214.00 €	Thu 17 Apr 25
Capecitabine, 99% REF: AC-45624CAS: 154361-50-9	99%	239.00 €	Mon 21 Apr 25
Capecitabine REF: 86-MM0992.00CAS: 154361-50-9	- - -	167.00 €	Mon 21 Apr 25
Capecitabine REF: 3B-C2878CAS: 154361-50-9	>98.0%(T)(HPLC)	75.00 €~224.00 €	Mon 21 Apr 25
Capecitabine REF: TR-C175650CAS: 154361-50-9	- - -	101.00 €~145.00 €	Mon 28 Apr 25
Capecitibine REF: 10-F048966CAS: 154361-50-9	99.0%	To inquire	Mon 28 Apr 25
Capecitabine - Bio-X ™ REF: 3D-BC164277CAS: 154361-50-9	Min. 95%	147.00 €	Tue 29 Apr 25
Capecitabine REF: 3D-ND09160CAS: 154361-50-9	Min. 95%	149.00 €~2,198.00 €	Tue 29 Apr 25