CAS 16676-29-2

Naltrexone hydrochloride

Description:

Naltrexone hydrochloride is an opioid antagonist primarily used in the management of opioid dependence and alcohol use disorder. It functions by blocking the effects of opioids at the receptor sites in the brain, thereby reducing cravings and the euphoric effects associated with opioid use. This compound is a white to off-white crystalline powder that is soluble in water and has a molecular formula that reflects its complex structure. Naltrexone hydrochloride is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. The substance is well-tolerated in most patients, although it may cause side effects such as nausea, headache, and dizziness. It is important to note that naltrexone should not be used in individuals currently dependent on opioids, as it can precipitate withdrawal symptoms. Overall, naltrexone hydrochloride plays a significant role in addiction treatment protocols, contributing to recovery and relapse prevention strategies.

Formula: C₂₀H₂₃NO₄·ClH

InChI: InChI=1S/C20H23NO4.ClH/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,15,18,22,24H,1-2,5-10H2;1H/t15-,18+,19+,20-;/m1./s1

InChI key: InChIKey=RHBRMCOKKKZVRY-ITLPAZOVSA-N

SMILES: O[C@]12[C@@]34C=5C(O[C@]3(C(=O)CC1)[H])=C(O)C=CC5C[C@]2(N(CC6CC6)CC4)[H].Cl

Synonyms:

• (5Alpha)-17-(Cyclopropylmethyl)-3,14-Dihydroxy-4,5-Epoxymorphinan-6-One Hydrochloride
• (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
• Antaxone
• Depade
• En 1639A
• Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride (1:1), (5α)-
• Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride, (5α)-
• Morphinan-6-one, 17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-, hydrochloride
• Nalorex
• Naltrexone hcl
• Nih 8503
• ReVia

Naltrexone Hydrochloride

CAS: 16676-29-2

Formula: C₂₀H₂₃NO₄·HCl

Purity: >98.0%(GC)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 377.87

Ref: 3B-N1176

Naltrexone hydrochloride

CAS: 16676-29-2

A congener of naloxone and also an opioid antagonist

Formula: C₂₀H₂₄ClNO₄

Color and Shape: Off-white to pale brown, Powder

Molecular weight: 377.87

Ref: 02-J60590

Naltrexone.HCl

CAS: 16676-29-2

Color and Shape: Neat

Ref: LP-M-819-HC-10

Naltrexone Hydrochloride

CAS: 16676-29-2

Color and Shape: Neat

Ref: 61-FOR0233.00

Naltrexone.HCl, 1mg/ml in Methanol (as free base)

CAS: 16676-29-2

Color and Shape: Single Solution

Ref: LP-M-819-HC-1LM

Naltrexone Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 16676-29-2

Color and Shape: Single Solution

Ref: 61-AMP0233.00-01

NALTREXONE HYDROCHLORIDE CRS

CAS: 16676-29-2

NALTREXONE HYDROCHLORIDE CRS

Formula: C₂₀H₂₄ClNO₄

Color and Shape: Powder

Molecular weight: 377.8619

Ref: 41-Y0000400

Naltrexone hydrochloride

CAS: 16676-29-2

Naltrexone hydrochloride (Naltrexone HCl) is a synthetic opioid antagonist used in the prevention of relapse of opiate addiction and alcoholism.

Formula: C₂₀H₂₄ClNO₄

Purity: 98.72% - 99.65%

Color and Shape: White Crystalline Powder

Molecular weight: 377.862

Ref: TM-T0963

Naltrexone HCl

CAS: 16676-29-2

Formula: C₂₀H₂₃NO₄·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 341.41 36.46

Ref: 4Z-N-0131

Naltrexone Hydrochloride

Controlled Product

CAS: 16676-29-2

Formula: C₂₀H₂₃NO₄·ClH

Color and Shape: Neat

Molecular weight: 377.86

Ref: 86-MM0233.00

Naltrexone hydrochloride, Ph. Eur. grade

CAS: 16676-29-2

Formula: C₁₉H₂₁NO₄·HCl·xH₂O

Purity: 98.0 - 102.0 %

Color and Shape: White or almost white powder

Molecular weight: 377.86

Ref: 7W-GP1217

Naltrexone hydrochloride, 98%

CAS: 16676-29-2

Formula: C₁₉H₂₁NO₄·HCl·xH₂O

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 377.86

Ref: 7W-GP1243

Naltrexone Hydrochloride

CAS: 16676-29-2

Applications Nonselective opioid receptor antagonist; congener of Naloxone.
References Maickel, R.P., et al.: Ann. N.Y. Acad. Sci., 281, 321 (1976), Gritz, E.R., et al.: Clin. Pharmacol. Ther. 19, 773 (1976), Gonzales, J.P., et al.: Drugs, 35, 192 (1988), Berg, B.J., et al.: Drug Saf., 15, 274 (1996),

Formula: C₂₀H₂₃NO₄·ClH

Color and Shape: White

Molecular weight: 377.86

Ref: TR-N285750

Naltrexone hydrochloride

Controlled Product

CAS: 16676-29-2

μ-opioid receptor antagonist; management of alcohol dependence, opioid addiction

Formula: C₂₀H₂₃NO₄•HCl

Purity: (%) Min. 98%

Color and Shape: Powder

Molecular weight: 377.86 g/mol

Ref: 3D-FN26133

Naltrexone HCl - Bio-X ™

Controlled Product

CAS: 16676-29-2

Naltrexone is a derivate of noroxymorphone and is a narcotic antagonist used for the treatment of opioid overdose. This drug is a pure opioid antagonist and blocks the effects of endogenous opioids.

Formula: C₂₀H₂₄ClNO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 377.86 g/mol

Ref: 3D-BN164635