CAS 16676-29-2: Naltrexone hydrochloride
Description:Naltrexone hydrochloride is an opioid antagonist primarily used in the management of opioid dependence and alcohol use disorder. It functions by blocking the effects of opioids at the receptor sites in the brain, thereby reducing cravings and the euphoric effects associated with opioid use. This compound is a white to off-white crystalline powder that is soluble in water and has a molecular formula that reflects its complex structure. Naltrexone hydrochloride is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. The substance is well-tolerated in most patients, although it may cause side effects such as nausea, headache, and dizziness. It is important to note that naltrexone should not be used in individuals currently dependent on opioids, as it can precipitate withdrawal symptoms. Overall, naltrexone hydrochloride plays a significant role in addiction treatment protocols, contributing to recovery and relapse prevention strategies.
Formula:C20H23NO4·ClH
InChI:InChI=1S/C20H23NO4.ClH/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,15,18,22,24H,1-2,5-10H2;1H/t15-,18+,19+,20-;/m1./s1
InChI key:InChIKey=RHBRMCOKKKZVRY-ITLPAZOVSA-N
SMILES:Cl.O=C1CCC2(O)C3N(CCC42C5=C(OC14)C(O)=CC=C5C3)CC6CC6
- Synonyms:
- (5Alpha)-17-(Cyclopropylmethyl)-3,14-Dihydroxy-4,5-Epoxymorphinan-6-One Hydrochloride
- (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
- Antaxone
- Depade
- En 1639A
- Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride (1:1), (5α)-
- Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride, (5α)-
- Morphinan-6-one, 17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-, hydrochloride
- Nalorex
- Naltrexone hcl
- See more synonyms
- Nih 8503
- ReVia
- Trexan
