CAS 23327-57-3
:(±)-Nefopam hydrochloride
Description:
(±)-Nefopam hydrochloride is a synthetic compound primarily recognized for its analgesic properties. It is classified as a non-opioid analgesic and is often used to manage pain, particularly in cases where traditional opioids may not be suitable. The substance exhibits a unique mechanism of action, primarily through the inhibition of the reuptake of neurotransmitters such as serotonin, norepinephrine, and dopamine, which contributes to its pain-relieving effects. Chemically, it is a racemic mixture, meaning it contains equal parts of two enantiomers, which can exhibit different pharmacological activities. Nefopam hydrochloride is typically administered in its hydrochloride salt form, enhancing its solubility and stability. The compound is known for its relatively low incidence of side effects compared to opioids, making it a valuable alternative in pain management. However, it may still cause some adverse effects, including nausea and dizziness. As with any medication, its use should be guided by a healthcare professional, considering individual patient needs and potential interactions with other medications.
Formula:C17H19NO·ClH
InChI:InChI=1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H
InChI key:InChIKey=CNNVSINJDJNHQK-UHFFFAOYSA-N
SMILES:CN1CC=2C(C(OCC1)C3=CC=CC=C3)=CC=CC2.Cl
Synonyms:- 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride
- 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (1:1)
- 3,4,5,6-Tetrahydro-5-Methyl-1-Phenyl-1H-2,5-Benzoxazocine Hydrochloride
- 3-Methyl-7-Phenyl-6-Oxa-3-Azabicyclo[6.4.0]Dodeca-8,10,12-Triene Hydrochloride
- 5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocin-5-ium chloride
- Acupan
- Fenazoxine
- Fenazoxine hydrochloride
- Nefopam HCl
- R 738
- Nefopam hydrochloride
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Found 16 products.
Nefopam Hydrochloride
CAS:Formula:C17H19NO·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:289.805-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:289.79998779296875(±)-Nefopam (hydrochloride)
CAS:Formula:C17H20ClNOPurity:98%Color and Shape:SolidMolecular weight:289.7998Nefopam hydrochloride
CAS:<p>Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.</p>Formula:C17H20ClNOPurity:99.32% - 99.85%Color and Shape:SolidMolecular weight:289.8Nefopam hydrochloride
CAS:Formula:C17H19NO·HClPurity:≥ 98.0%Color and Shape:White to off-white or beige powderMolecular weight:289.80Nefopam HCl
CAS:Formula:C17H19NO·HClColor and Shape:White To Off-White SolidMolecular weight:253.35 36.46Nefopam-d4 HCl
CAS:Formula:C17H15D4NO·HClColor and Shape:White To Off-White SolidMolecular weight:257.37 36.46Nefopam Hydrochloride
CAS:Controlled ProductFormula:C17H19NO·ClHColor and Shape:NeatMolecular weight:289.80Nefopam Hydrochloride
CAS:Controlled Product<p>Applications A cyclized analog of orphenadrine and diphenhydramine; representative of a new class of centrally acting skeletal muscle relaxants, the benzoxazocines. Analgesic; antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bassett, et al.: Br. J. Pharmacol., 37, 69 (1969), Klohs, et al.: Arzneim.-Forsch., 22, 132 (1972), Hell, et al.: Drugs, 19, 249 (1980),<br></p>Formula:C17H19NO·ClHColor and Shape:White To Off-WhiteMolecular weight:289.80Nefopam HCl - Bio-X ™
CAS:<p>Nefopam is a non-narcotic analgesic drug that has been used in the treatment of chronic pain. It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). Nefopam is also a nasal drug that relieves pain by blocking neurokinin 1 receptor, which reduces the production of prostaglandins. Nefopam acts in the brain and spinal cord to relieve pain through different mechanisms such as antinociceptive effects from triple monoamine reuptake inhibition, and antihyperalgesic activity through modulation of glutamatergic transmission.</p>Formula:C17H19NO·HClPurity:Min. 95%Color and Shape:PowderMolecular weight:289.8 g/molNefopam hydrochloride
CAS:<p>3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride (THPP) is a drug that is used as an analgesic and anti-inflammatory agent. THPP interacts with nonsteroidal anti-inflammatory drugs (NSAIDs) to cause neuronal death. It has been shown to inhibit the plate test for prostaglandin synthesis in human erythrocytes. The disulfide bond between cysteine residues on the protein molecule is susceptible to oxidative cleavage by reactive oxygen species from reactive oxygen species such as hydrogen peroxide and lipid peroxidation products. This can lead to the formation of a thiolate ion and a sulfenic acid intermediate. THPP is also known to produce chronic oral toxicity in rats at doses of 837 mg/kg/day for two months. A chemiluminescence method was used to measure the reaction</p>Formula:C17H20ClNOPurity:Min. 95%Color and Shape:PowderMolecular weight:289.8 g/molN-Hydroxymethyl Nefopam N-Oxide
CAS:Formula:C17H19NO3Color and Shape:White To Off-White SolidMolecular weight:285.35Ref: 4Z-N-3710
Discontinued product
![5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF241971.jpg&w=3840&q=75)
