CAS 2447-57-6: Sulfadoxine

Description: Sulfadoxine is a sulfonamide antibiotic that is primarily used in combination with pyrimethamine for the treatment of malaria, particularly in areas where resistance to other antimalarial drugs is prevalent. It functions by inhibiting the bacterial enzyme dihydropteroate synthase, which is crucial for folate synthesis, thereby disrupting nucleic acid synthesis in susceptible organisms. Sulfadoxine is characterized by its relatively long half-life, allowing for once-weekly dosing in some treatment regimens. The compound is typically administered orally and is well-absorbed in the gastrointestinal tract. It is known for its potential side effects, which can include allergic reactions, skin rashes, and hematological disorders. Additionally, sulfadoxine may interact with other medications, necessitating careful consideration in polypharmacy situations. Its use is often monitored due to the risk of developing resistance, and it is contraindicated in individuals with a known hypersensitivity to sulfonamides. Overall, sulfadoxine remains an important agent in the fight against malaria, particularly in combination therapies.

Formula: C₁₂H₁₄N₄O₄S

InChI: InChI=1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)

InChI key: InChIKey=PJSFRIWCGOHTNF-UHFFFAOYSA-N

SMILES: O=S(=O)(NC=1N=CN=C(OC)C1OC)C2=CC=C(N)C=C2

Synonyms:

• 4,5-Dimethoxy-6-sulfanilamidopyrimidine
• 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
• 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzensulfonamide
• 4-Sulfanilamido-5,6-dimethoxypyrimidine
• 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
• 6-(4-Aminobenzenesulfonamide)-4,5-dimethoxypyrimidine
• 6-(4-Aminobenzenesulfonamido)-4,5-dimethoxypyrimidine
• Benzenesulfonamide, 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)-
• Fanasil
• Fanasulf
• Fansidar (suldfadoxine and pyrimethamine)
• Fanzil
• N-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
• N1-(5,6-dimethoxypyrimidin-4-yl)sulphanilamide
• N1-5,6-Dimethoxy-4-pyrimidinylsulfanilamide
• N¹-5,6-Dimethoxy-4-pyrimidinylsulfanilamide
• Orthosulfin
• Ro 4-4393
• Sanasil
• Sulfadimoxine
• Sulfadimoxine Fanasil
• Sulfadoxin
• Sulfadoxina
• Sulfadoxine (Sulformethoxine)
• Sulfanilamide, N1-(5,6-dimethoxy-4-pyrimidinyl)-
• Sulfanilamide, N¹-(5,6-dimethoxy-4-pyrimidinyl)-
• Sulformethoxine
• Sulformetoxin
• Sulformetoxine
• Sulforthodimethoxine
• Sulforthomidine
• Sulphadoxine
• Wr 4073

Sulfadoxin

CAS: 2447-57-6

• Formula: C₁₂H₁₄N₄O₄S
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 310.33

Sulfadoxine, 98%

CAS: 2447-57-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. …

• Formula: C₁₂H₁₄N₄O₄S
• Purity: 98%
• Molecular weight: 310.33

Sulfadoxine CRS

CAS: 2447-57-6

• Formula: C₁₂H₁₄N₄O₄S
• Color and Shape: Crystalline Powder. White. Crystals. Powder.
• Molecular weight: 310.329

Sulfadoxine

CAS: 2447-57-6

Sulfonamides used as drugs

• Formula: C₁₂H₁₄N₄O₄S
• Color and Shape: Off-White White Yellow Powder
• Molecular weight: 310.07358

Benzenesulfonamide, 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)-

CAS: 2447-57-6

• Formula: C₁₂H₁₄N₄O₄S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 310.3289600000001

Sulfadoxine

CAS: 2447-57-6

Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with …

• Formula: C₁₂H₁₄N₄O₄S
• Purity: 99.67%
• Color and Shape: White Or White Crystalline Powder
• Molecular weight: 310.33

Sulfadoxine

CAS: 2447-57-6

• Formula: C₁₂H₁₄N₄O₄S
• Color and Shape: White to off-white powder or crystals
• Molecular weight: 310.33

Sulfadoxin

CAS: 2447-57-6

• Molecular weight: 310.33g/mol

Sulfadoxine-d4 (benzene-d4)(

CAS: 1330266-05-1 2447-57-6

• Purity: 98 atom % D
• Molecular weight: 314.35

Sulfadoxine

CAS: 2447-57-6

• Formula: C₁₂H₁₄N₄O₄S
• Color and Shape: Neat
• Molecular weight: 310.33

Ministry of Agriculture Veterinary Drug Mixture 348 10 µg/mL in Acetonitrile:Water

CAS: 102-65-8 112398-08-0 115550-35-1 122-11-2 1220-83-3 127-69-5 127-71-9 127-79-7 144-80-9 144-83-2 23282-55-5 2447-57-62462-17-1 526-08-9 57-67-0 59-40-5 63-74-1 68-35-9 70458-92-3 723-46-6 738-70-5 82419-36-1 91296-86-5 93106-60-6 98079-51-7

• Color and Shape: Mixture

Sulfadoxin 1000 µg/mL in Acetonitrile

CAS: 2447-57-6

• Formula: C₁₂H₁₄N₄O₄S
• Color and Shape: Single Solution
• Molecular weight: 310.33

Sulfonamides Mixture for GB/T 21316-2007 100 µg/mL in Acetonitrile

CAS: 122-11-2 122-16-7 1220-83-3 127-69-5 127-71-9 127-79-7 144-80-9 144-82-1 144-83-2 2447-57-6515-64-0 526-08-9 57-67-0 57-68-1 59-40-5 651-06-9 68-35-9 72-14-0 723-46-6 729-99-7 738-70-5 80-32-0 80-35-3

• Color and Shape: Mixture

PharmaVetResiMix 4 Sulfonamides-v21 10 µg/mL in Methanol

CAS: 100-90-3 122-11-2 1220-83-3 127-71-9 127-79-7 144-82-1 144-83-2 2447-57-6515-64-0 57-67-0 57-68-1 59-40-5 63-74-1 651-06-9 68-35-9 72-14-0 723-46-6 729-99-7 80-08-0 80-32-0 80-35-3

• Color and Shape: Mixture

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3 113507-06-5 115550-35-1 117704-25-3 119478-55-6 122-11-2 1220-83-3 123997-26-2 127-71-9 127-79-7 144-82-1 144-83-2 14698-29-4 148-79-8 149676-40-4 155569-91-8 19562-30-2 20559-55-1 2447-57-628657-80-9 31430-15-6 31431-39-7 389-08-2 42835-25-6 43210-67-9 515-64-0 51940-44-4 53716-50-0 54029-12-8 54965-21-8 57-67-0 57-68-1 58306-30-2 59-40-5 63-74-1 651-06-9 68-35-9 68786-66-3 70288-86-7 70458-96-7 71751-41-2 72-14-0 723-46-6 729-99-7 74011-58-8 75184-71-3 79660-72-3 80-08-0 80-32-0 80-35-3 80983-34-2 82419-36-1 85721-33-1 88254-99-3 91296-86-5 91296-87-6 93106-60-6 948-71-0 98079-52-8

• Color and Shape: Mixture

Sulfadoxine

CAS: 2447-57-6

• Formula: C₁₂H₁₄N₄O₄S
• Color and Shape: Neat
• Molecular weight: 310.33

GB/T 20759-2006 Sulfonamides Mixture 583 100 µg/mL in Methanol

CAS: 122-11-2 1220-83-3 127-69-5 127-79-7 144-80-9 144-82-1 144-83-2 2447-57-6526-08-9 57-68-1 651-06-9 68-35-9 72-14-0 723-46-6 80-32-0 80-35-3

• Color and Shape: Mixture

Sulfadoxine

CAS: 2447-57-6

• Formula: C₁₂H₁₄N₄O₄S
• Molecular weight: 310.33

Sulfadoxine

CAS: 2447-57-6

Applications Used as an antibacterial. References Kapoor, V.K., et al.: Anal. Profiles Drug Subs., 17, …

• Formula: C₁₂H₁₄N₄O₄S
• Color and Shape: White
• Molecular weight: 310.33

Sulfadoxine

CAS: 2447-57-6

Please enquire for more information about Sulfadoxine including the price, delivery time and more detailed …

• Formula: C₁₂H₁₄N₄O₄S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 310.33 g/mol