![2-[2-(hydroxymethyl)-5-nitro-1H-imidazol-1-yl]ethanol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F57907-1-2-hydroxyethyl-2-hydroxymethyl-5-nitroimidazole.webp&w=3840&q=75)
CAS 4812-40-2
:2-[2-(hydroxymethyl)-5-nitro-1H-imidazol-1-yl]ethanol
Description:
2-[2-(Hydroxymethyl)-5-nitro-1H-imidazol-1-yl]ethanol, with the CAS number 4812-40-2, is a chemical compound characterized by its imidazole ring, which is a five-membered heterocyclic structure containing nitrogen atoms. This compound features a hydroxymethyl group and a nitro group, contributing to its unique chemical properties and potential biological activity. It is typically a solid at room temperature and is soluble in polar solvents due to the presence of hydroxyl groups. The nitro group can impart significant reactivity, making it a candidate for various chemical reactions, including reduction and nucleophilic substitution. Its structure suggests potential applications in pharmaceuticals, particularly in the development of antimicrobial agents or other therapeutic compounds. The presence of both hydroxymethyl and nitro functionalities may influence its interaction with biological systems, potentially affecting its pharmacokinetics and pharmacodynamics. As with many chemical substances, safety data should be consulted to understand its handling and toxicity profiles.
Formula:C6H9N3O4
InChI:InChI=1/C6H9N3O4/c10-2-1-8-5(4-11)7-3-6(8)9(12)13/h3,10-11H,1-2,4H2
InChI key:InChIKey=AEHPOYAOLCAMIU-UHFFFAOYSA-N
SMILES:C(CO)N1C(N(=O)=O)=CN=C1CO
Synonyms:- 1-(2-Hydroxyethyl)-2-(hydroxymethyl)-5-nitroimidazole
- 1H-imidazole-1-ethanol, 2-(hydroxymethyl)-5-nitro-
- 2-(Hydroxymethyl)-5-nitro-1H-imidazole-1-ethanol
- 2-[2-(Hydroxymethyl)-5-nitro-1H-imidazol-1-yl]ethan-1-ol
- Hydroxymetronidazole
- Imidazole-1-ethanol, 2-(hydroxymethyl)-5-nitro-
- 2-[2-(Hydroxymethyl)-5-nitro-1H-imidazol-1-yl]ethanol
- Metronidazole-OH,1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole, Hydroxymetronidazole, MNZOH
- 1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole (Hydroxy
- Metronidazole-hydroxy solution,1000ppm solution,100ppm
- Hydroxy MetronidazoleQ: What is
- Hydroxy Metronidazole D2Q: What is
- 2-hydroxymethyl-5-nitro-imidazole-1-ethano
- Hydroxy Metronidazo
- Hydroxy Metronidazole
- Hydroxy Metronidazole D2 Q: What are the applications of
- 4-Hydroxy-2-methyl-5-nitro-1H-imidazole-1-ethanol
- Metronidazole-hydroxy solution,100ppm
- Hydroxy Metronidazole Q: What are the applications of
- ROXYMETHYL-5-NITROIMIDAZOLE
- MNZOH, Hydroxy metronidazole Solution, 100ppm
- Hydroxy Metronidazole D2
- 1-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole, Hydroxymetronidazole, MNZOH
- 2-(HydroxyMethyl)-5-nitro-
- Metronidazole EP Impurity H
- Hydroxy Metronidazole D2 Q: What is the storage condition of
- Hydroxy Metronidazole Q: What is the storage condition of
- 1-(2-Hydroxyethyl)-2-hydroxymethyl-
- HYDROXY METRONIDAZOLE
- MNZOH
- Hydroxy Metronidazole D2 Q: What is the CAS Number of
- Hydroxy Metronidazole Q: What is the CAS Number of
- Metronidazole-hydroxy
- Metronidazole Impurity H
- Metronidazole-OH
- See more synonyms
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Found 16 products.
1-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-5-NITROIMIDAZOLE
CAS:Formula:C6H9N3O4Purity:95%Color and Shape:SolidMolecular weight:187.1534Hydroxymetronidazole
CAS:Hydroxymetronidazole (Metronidazole-OH) is a nitroimidazole compound and metabolite of Metronidazole, commonly used in poultry research for bacterial and protozoal diseases, and in studies of swine dysentery and genital trichomoniasis in cattle.Formula:C6H9N3O4Color and Shape:SolidMolecular weight:187.151-(2-Hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole (Hydroxymetronidazole)
CAS:Controlled ProductFormula:C6H9N3O4Color and Shape:NeatMolecular weight:187.15GB/T 21318-2007, SN/T 1928-2007 10 Nitroimidazoles 100 µg/mL in Methanol
CAS:Controlled ProductColor and Shape:ColourlessPharmaVetResiMix 7 Nitroimidazoles-v13 10 µg/mL in Methanol
CAS:Controlled Product- 14885-29-1
- 16773-42-5
- 19387-91-8
- 35175-14-5
- 42116-76-7
- 443-48-1
- 4812-40-2
- 551-92-8
- 59-87-0
- 67-45-8
- 70028-95-4
- 7681-76-7
- 936-05-0
Color and Shape:ColourlessMetronidazole-hydroxy 100 µg/mL in Acetonitrile
CAS:Formula:C6H9N3O4Color and Shape:Single SolutionMolecular weight:187.15Metronidazole-hydroxy 100 µg/mL in Methanol
CAS:Controlled ProductFormula:C6H9N3O4Color and Shape:ColourlessMolecular weight:187.15Hydroxy Metronidazole
CAS:Applications A metabolite of Metronidazole (M338880).
References Haller, I., et al.: Antimicrob. Agents Chemother., 22, 165 (1982), Gibson, R., et al.: Clin. Chem., 30, 784 (1984), Kuti, J., et al.: Pharmacotherapy, 25, 935 (2005),Formula:C6H9N3O4Color and Shape:WhiteMolecular weight:187.15Hydroxy metronidazole
CAS:Hydroxy metronidazole is a nitroimidazole drug that is used as an antibiotic against bacterial infections. It is also used for the treatment of protozoal infections and as a pre- and post-operative medication. Hydroxy metronidazole has synergistic effects with ceftriaxone, which are due to its ability to inhibit DNA synthesis by chemical inhibition of bacterial DNA gyrase. The drug has been shown to be genotoxic in humans, mice, and rats. It can lead to genotoxic effects in the form of chromosomal aberrations in human lymphocytes and micronuclei in the bone marrow cells of mice following acute exposure. Hydroxy metronidazole also inhibits protein synthesis in bacteria by binding to ribosomes at the A site, blocking entry of amino acid into the ribosome. This leads to bacterial cell death by inhibiting protein synthesis.
Formula:C6H9N3O4Purity:Min. 95%Molecular weight:187.15 g/mol
