CAS 50-28-2: Estradiol

Description: Estradiol, with the CAS number 50-28-2, is a potent estrogen steroid hormone primarily produced in the ovaries, although it is also synthesized in smaller amounts in the adrenal glands and testes. It plays a crucial role in the regulation of the menstrual cycle and reproductive system in females, as well as influencing various physiological processes in both sexes, including bone density, fat distribution, and cardiovascular health. Chemically, estradiol is characterized by its structure as a phenolic compound with a steroid backbone, featuring a hydroxyl group at the C-3 position and an aromatic A-ring. It is lipophilic, allowing it to easily cross cell membranes and bind to estrogen receptors, initiating a range of biological responses. Estradiol is also involved in various therapeutic applications, including hormone replacement therapy and treatment of certain hormone-sensitive cancers. Its synthesis and metabolism are tightly regulated, and imbalances can lead to various health issues, including reproductive disorders and osteoporosis.

Formula: C₁₈H₂₄O₂

InChI: InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

InChI key: InChIKey=VOXZDWNPVJITMN-ZBRFXRBCSA-N

SMILES: OC1=CC=C2C(=C1)CCC3C2CCC4(C)C(O)CCC34

Synonyms:

• (+)-3,17β-Estradiol
• (17β)-Estra-1,3,5(10)-triene-3,17-diol
• (8Alpha,9Beta,13Alpha,14Beta,17Alpha)-Estra-1,3,5(10)-Triene-3,17-Diol
• (8R,9S,13S,14S,17S)-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
• 1,3,5-Estratriene-3,17Beta-Diol
• 13β-Methyl-1,3,5(10)-gonatriene-3,17β-ol
• 17Beta-Estradiol
• 17β-Estradiol
• 17β-Oestradiol
• 3,17-Epidihydroxyestratriene
• 3,17Beta-Dihydroxy-1,3,5(10)-Estratriene
• 3,17β-Dihydroxyestra-1,3,5(10)-triene
• Aerodiol
• Alora
• Altrad
• Aquadiol
• Bardiol
• Benzogynestry
• Beta-Estradiol
• Climaderm
• Climara
• Compudose
• Corpagen
• Dermestril
• Destradiol
• Dihydrofolliculin
• Dihydromenformon
• Dihydrotheelin
• Dihydroxyestrin
• Dimenformon
• Diogyn
• Diogynets
• Divigel
• Elestrim
• Encore
• Estasorb
• Estra-1,3,5(10)-triene-3,17-diol
• Estra-1,3,5(10)-triene-3,17β-diol
• Estrace
• Estraderm
• Estradiol
• Estradiol-17β
• Estradot
• Estraldine
• Estrapatch
• Estredox
• Estreva
• Estring
• Estroclim
• Estrogel
• Estropause
• Estrovite
• Evamist
• Evorel
• FemSeven
• Femanest
• Femestral
• Femogen
• Fempatch
• Follicyclin
• Gelestra
• Ginosedol
• Gynergon
• Gynodiol
• Gynoestryl
• Imvexxy
• Innofem
• Lamdiol
• Macrodiol
• Menorest
• Menostar
• Nordicol
• Oesclim
• Oestergon
• Oestra-1,3,5(10)-triene-3,17β-diol
• Oestradiol
• Oestrogel
• Oestroglandol
• Ovahormon
• Ovasterol
• Ovastevol
• Ovocyclin
• Ovocylin
• Perlatanol
• Primofol
• Profoliol
• Progynon
• Sprediol
• Syndiol
• Systen
• Vagifem
• Vivelle
• Vivelle-Dot
• Zesteem
• Zumenon
• Estra-1,3,5(10)-triene-3,17-diol (17β)-

β-Estradiol

CAS: 50-28-2

• Formula: C₁₈H₂₄O₂
• Purity: >97.0%(GC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 272.39

β-Estradiol, 99% (dry wt.), ca 3% water

CAS: 50-28-2

β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic …

• Formula: C₁₈H₂₄O₂
• Purity: 99%
• Color and Shape: Powder, White
• Molecular weight: 272.39

Estradiol

CAS: 50-28-2

Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility …

• Formula: C₁₈H₂₄O₂
• Purity: 98.25% - 99.58%
• Color and Shape: White Crystalline Powder Prisms From 80% Alcohol Solid
• Molecular weight: 272.38

(17β)-Estra-1,3,5(10)-triene-3,17-diol

CAS: 50-28-2

• Formula: C₁₈H₂₄O₂
• Purity: %
• Color and Shape: Solid
• Molecular weight: 272.382

Estradiol-13C2-d2 (Estradiol Valerate EP Impurity A-13C2-d2, Estriol EP Impurity D-13C2-d2, Ethinylestradiol EP Impurity D-13C2-d2)

CAS: 50-28-2

• Formula: C₁₆₁₃C₂H₂₂D₂O₂
• Molecular weight: 276.38

Estradiol (Estradiol Valerate EP Impurity A, Estriol EP Impurity D, Ethinylestradiol EP Impurity D)

CAS: 50-28-2

• Formula: C₁₈H₂₄O₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 272.39

Estradiol

CAS: 50-28-2

• Formula: C₁₈H₂₄O₂
• Purity: ≥ 97.0% (dried basis)
• Color and Shape: White or off-white powder
• Molecular weight: 272.39

17-β-Estradiol 100 µg/mL in Acetonitrile

CAS: 50-28-2

• Formula: C₁₈H₂₄O₂
• Color and Shape: Single Solution
• Molecular weight: 272.38

Estradiol

CAS: 50-28-2

• Formula: C₁₈H₂₄O₂
• Purity: 95%~99%
• Color and Shape: Powder
• Molecular weight: 272.388

17-β-Estradiol

CAS: 50-28-2

• Formula: C₁₈H₂₄O₂
• Color and Shape: Neat
• Molecular weight: 272.38

GB 31660.2-2019 Antibiotics Mixture 168 30-100 µg/mL in Methanol

CAS: 140-66-9 25154-52-3 50-27-1 50-28-253-16-7 56-53-1 57-63-6 80-05-7

• Color and Shape: Mixture

β-Estradiol, 98%

CAS: 50-28-2

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₈H₂₄O₂
• Purity: 98%
• Color and Shape: White to off-white, Powder
• Molecular weight: 272.39

(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol

CAS: 50-28-2

• Purity: 97.0%
• Color and Shape: Solid, White powder
• Molecular weight: 272.38800048828125

17β-Estradiol

CAS: 50-28-2

Impurity Ethinylestradiol EP Impurity D Applications 17b-Estradiol is the major estrogen (1) secreted by the …

• Formula: C₁₈H₂₄O₂
• Color and Shape: White
• Molecular weight: 272.38

b-Estradiol

CAS: 50-28-2

Please enquire for more information about b-Estradiol including the price, delivery time and more detailed …

• Formula: C₁₈H₂₄O₂
• Purity: Min. 97 Area-%
• Color and Shape: Powder
• Molecular weight: 272.38 g/mol

Estradiol-(13,14,15,16,17,18-13C6)

CAS: 50-28-2

• Formula: C₁₂C₆H₂₄O₂
• Color and Shape: Neat
• Molecular weight: 278.34