CAS 57-63-6

Ethinylestradiol

Description:

Ethinylestradiol is a synthetic estrogen, primarily used in hormonal contraceptives and hormone replacement therapy. It is characterized by its potent estrogenic activity, which is significantly stronger than that of natural estradiol. Ethinylestradiol is a white to off-white crystalline powder that is poorly soluble in water but soluble in organic solvents such as ethanol and acetone. Its chemical formula is C20H24O2, and it has a molecular weight of approximately 296.4 g/mol. The compound features an ethynyl group at the C17 position, which enhances its oral bioavailability and metabolic stability compared to natural estrogens. Ethinylestradiol acts by binding to estrogen receptors, influencing various physiological processes, including the regulation of the menstrual cycle and the development of secondary sexual characteristics. Due to its estrogenic effects, it can also have side effects, including an increased risk of thromboembolic events. As a widely used pharmaceutical agent, it is essential to consider its pharmacokinetics, potential interactions, and contraindications in clinical applications.

Formula: C₂₀H₂₄O₂

InChI: InChI=1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m1/s1

InChI key: InChIKey=BFPYWIDHMRZLRN-SLHNCBLASA-N

SMILES: C[C@@]12[C@]([C@]3([C@](CC1)(C=4C(CC3)=CC(O)=CC4)[H])[H])(CC[C@]2(C#C)O)[H]

Synonyms:

• (17Alpha)-17-Ethynylestra-1,3,5(10)-Triene-3,17-Diol
• (17Beta)-17-Ethynylestra-1,3,5(10)-Triene-3,17-Diol
• (17α)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol
• (8Alpha,13Alpha,17Beta)-17-Ethynylestra-1,3,5(10)-Triene-3,17-Diol
• (8Xi,9Xi,14Xi,17Beta)-17-Ethynylestra-1,3,5(10)-Triene-3,17-Diol
• 17-Ethinyl-3,17-estradiol
• 17-Ethinylestradiol
• 17-Ethynyl Estradiol
• 17-Ethynyl-3,17-dihydroxy-1,3,5-oestratriene
• 17-Ethynylestra-1,3,5(10)-Triene-3,17-Diol
• 17-Ethynylestra-1,3,5(10)-triene-3,17β-diol
• 17-Ethynylestradiol
• 17-Nor-17α-pregna-1,3,5-(10)-trien-20-yne-3,17-diol
• 17A-Ethynyl-1,3,5(10)-Estratriene-3,17B-Diol
• 17Alpha-Ethynyl-3,17-Dihydroxy-Delta-(Sup1,3,5)-Estratriene
• 17alpha-Ethynyl-3-hydroxy-1,3,5(10)-estratrien-17beta-ol
• 17α-Ethinyl estradiol (EE2)
• 17α-Ethinyl-1,3,5(10)-estratriene-3,17-diol
• 17α-Ethinyl-17β-estradiol
• 17α-Ethinyl-3,17-dihydroxy-Δ1,3,5-estratriene
• 17α-Ethinyl-3,17-dihydroxy-Δ^1,3,5-estratriene
• 17α-Ethinylestra-1,3,5(10)-triene-3,17β-diol
• 17α-Ethinylestradiol
• 17α-Ethynylestra-1,3,5(10)-triene-3,17β-diol
• 17α-Ethynylestra-3,17β-diol
• 17α-Ethynylestradiol
• 19-Nor-17Alpha-Pregna-1,3,5(10)-Trien-20-Yne-3,17,Diol
• 19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol
• 19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17β-diol
• 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)-
• 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17α)-
• 3,17Beta-Dihydroxy-17Alpha-Ethynyl-1,3,5(10)-Estratriene
• Acetylene estradiol
• Amenoron
• Anovlar
• Chee-O-Gen
• Chee-O-Genf
• Diognat-E
• Diogyn-E
• Dyloform
• EE
• Esteed
• Estigyn
• Estinyl
• Eston-E
• Estone
• Estoral
• Estoral (Orion)
• Estorals
• Estra-1,3,5(10)-Triene-3,17Beta-Diol, 17Alpha-Ethynyl-
• Estradiol, 17-ethynyl-
• Estroals
• Ethidol
• Ethinoral
• Ethinyl estradiol
• Ethinyloestradiol
• Ethynyl estradiol
• Ethynylestradiol
• Ethynyloestradiol
• Eticyclin
• Eticyclol
• Etinestrol
• Etinestryl
• Etinilestradiol
• Etinoestryl
• Etistradiol
• Feminone
• Follicoral
• Ginestrene
• Gynofen
• Inestra
• Linoral
• Lynoral
• Menolyn
• Microfollin
• Neo-Estrone
• Novestrol
• Novinet
• Nsc 10973
• Oradiol
• Orestralyn
• Palonyl
• Perovex
• Primogyn
• Primogyn C
• Primogyn C(Or M)
• Primogyn M
• Progynon C
• Prosexol
• Roldiol
• Spanestrin

Ethynylestradiol

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Purity: >98.0%(HPLC)(T)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 296.41

Ref: 3B-E0037

ETHINYLESTRADIOL FOR SYSTEM SUITABILITY CRS

CAS: 57-63-6

ETHINYLESTRADIOL FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001124

Ethinylestradiol

CAS: 57-63-6

Ethinylestradiol

Formula: C₂₀H₂₄O₂

Purity: 97.0%

Color and Shape: White. To. Off-White

Molecular weight: 296.17763

Ref: 47-421

ETHINYLESTRADIOL RS

CAS: 57-63-6

ETHINYLESTRADIOL RS

Ref: 41-ICRS0305

ETHINYLESTRADIOL CRS

CAS: 57-63-6

ETHINYLESTRADIOL CRS

Color and Shape: Added Modified

Ref: 41-E1900000

Ethinyl Estradiol

CAS: 57-63-6

Estrogens and progestins

Formula: C₂₀H₂₄O₂

Color and Shape: White Light Yellow Crystalline Powder

Molecular weight: 296.17763

Ref: 45-1260001

Ethynyl estradiol

CAS: 57-63-6

Ethynyl estradiol is a semisynthetic alkylated ESTRADIOL with a 17-alpha-ethinyl substitution,which has high estrogenic potency when administered orally.

Formula: C₂₀H₂₄O₂

Purity: 99.06% - 99.75%

Color and Shape: Fine White To Creamy White Crystalline Powder

Molecular weight: 296.4034

Ref: TM-T1424

Ethynyl estradiol

CAS: 57-63-6

Ethynyl estradiol

Formula: C₂₀H₂₄O₂

Purity: >98%

Molecular weight: 296.4

Ref: 54-OR1030255

Ethinyl Estradiol

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Color and Shape: White To Off-White Solid

Molecular weight: 296.41

Ref: 4Z-E-099

Ethinylestradiol-d9

CAS: 57-63-6

Formula: C₂₀H₁₅D₉O₂

Molecular weight: 305.46

Ref: 4Z-E-4611

Ethynyl estradiol

CAS: 57-63-6

Ethynyl estradiol

Formula: C₂₀H₂₄O₂

Purity: ≥98%

Molecular weight: 296.4

Ref: 54-BUP16737

Ethinylestradiol

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 296.40

Ref: 7W-GP3324

17a-Ethinylestradiol 100 µg/mL in Acetonitrile

Controlled Product

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Color and Shape: Single Solution

Molecular weight: 296.4

Ref: 04-XA13245100AL

Ethinylestradiol

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Color and Shape: Neat

Molecular weight: 296.4

Ref: 86-MM0123.00

Ethinylestradiol

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Color and Shape: White To Off-White

Molecular weight: 296.4

Ref: 61-FOR0123.00

GB 31660.2-2019 Antibiotics Mixture 168 30-100 µg/mL in Methanol

Controlled Product

CAS: 140-66-9, 25154-52-3, 50-27-1, 50-28-2, 53-16-7, 56-53-1, 57-63-6, 80-05-7

Color and Shape: Mixture

Ref: 04-A50000168ME

17a-Ethinylestradiol

Controlled Product

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Color and Shape: Neat

Molecular weight: 296.4

Ref: 04-C13245100

Ethynyl Estradiol

Controlled Product

CAS: 57-63-6

Applications Ethynyl Estradiol, an oral contraceptive (1), is a synthetic steroid with high oral estrogenic potency. Used in estrogen replacement therapy. (2)This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Koetsawang, S. et al.: Contraception. 1982 March:25(3) p231-2412. Cuttler, L. et al.: J. Endocrinol. Metab. 1985 Jun;60(6):1087-92.

Formula: C₂₀H₂₄O₂

Color and Shape: Neat

Molecular weight: 296.4

Ref: TR-E685100

Ethynyl Estradiol-2,4,9,6,6,16,16-d7 (Major)

Controlled Product

CAS: 57-63-6

Applications Isotope labelled Ethynyl Estradiol (E685100), an oral contraceptive (1), is a synthetic steroid with high oral estrogenic potency. Used in estrogen replacement therapy (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Koetsawang, S. et al.: Contraception. 1982 March:25(3) p231-2412. Cuttler, L. et al.: J. Endocrinol. Metab. 1985 Jun;60(6):1087-92.

Formula: C₂₀H₁₇D₇O₂

Color and Shape: Neat

Molecular weight: 303.45

Ref: TR-E685104

Ethinylestradiol-13C2

CAS: 57-63-6

Formula: C₁₈₁₃C₂H₂₄O₂

Molecular weight: 298.39

Ref: 4Z-E-4610