CAS 51-21-8: 5-Fluorouracil

Description: 5-Fluorouracil (5-FU) is a synthetic pyrimidine analog that serves as an antimetabolite in cancer treatment, primarily targeting rapidly dividing cells. Its chemical formula is C4H3FN2O2, and it is characterized by the presence of a fluorine atom at the 5-position of the uracil ring, which alters its metabolic pathways. 5-FU is typically administered intravenously or topically, depending on the type of cancer being treated, such as colorectal, breast, and skin cancers. The mechanism of action involves the inhibition of thymidylate synthase, leading to a depletion of thymidine triphosphate and ultimately disrupting DNA synthesis and repair. 5-Fluorouracil is known for its side effects, which can include gastrointestinal disturbances, myelosuppression, and mucositis, due to its impact on normal rapidly dividing cells. Its efficacy can be enhanced when used in combination with other chemotherapeutic agents. As a potent chemotherapeutic agent, 5-FU remains a critical component in oncological pharmacotherapy.

Formula: C₄H₃FN₂O₂

InChI: InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)

InChI key: InChIKey=GHASVSINZRGABV-UHFFFAOYSA-N

SMILES: O=C1NC=C(F)C(=O)N1

Synonyms:

• 1-fluoropyrimidine-2,4(1H,3H)-dione
• 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-
• 2,4-Dihydroxy-5-fluoropyrimidine
• 2,4-Dioxo-5-fluoropyrimidine
• 5-Fluoracyl
• 5-Fluoro Uracil
• 5-Fluoro-1H-pyrimidine-2,4-dione
• 5-Fluoro-2,4(1H,3H)-pyrimidinedione
• 5-Fluoro-2,4-(1H,3H)-pyrimidindion
• 5-Fluoro-2,4-Pyrimidinedione
• 5-Fluoro-2,4-dihydroxypyrimidine
• 5-Fluoropyrimidine-2,4-Dione
• 5-Fluoropyrimidine-2,4-diol
• 5-Fluoruracil
• 5-Fu
• 5-Oncouracil
• Adrucil
• Arumel
• Carac
• Carzonal
• Efudex
• Efudix
• Efurix
• FU
• Fluoracil
• Fluoroblastin
• Fluoroplex
• Fluorouracil
• Fluorouracil, 5-
• Fluorouracile
• Fluorouracile Accord
• Fluorouracilo
• Fluorouracilum
• Fluoruracil
• Flurablastin
• Fluracedyl
• Fluracil
• Fluracilum
• Fluri
• Fluril
• Ftoruracil
• Kecimeton
• Nsc 19893
• Phthoruracil
• Phtoruracil
• Queroplex
• Ro 2-9757
• Sigma 03738
• Tegadifure
• Timazin
• U 8953
• Ulup
• Uracil, 5-Fluoro-

5-Fluorouracil

CAS: 51-21-8

• Formula: C₄H₃FN₂O₂
• Purity: >99.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 130.08

5-Fluorouracil, 99%

CAS: 51-21-8

5-Fluorouracil is used as an antitumor agent in the treatment of anal, breast, colorectal, oesophageal, …

• Formula: C₄H₃FN₂O₂
• Purity: 99%
• Color and Shape: Crystalline powder, White to pale cream
• Molecular weight: 130.08

Fluorouracil

CAS: 51-21-8

• Color and Shape: White

Fluorouracil CRS

CAS: 51-21-8

Fluorouracil RS

CAS: 51-21-8

• Formula: C₄H₃FN₂O₂
• Molecular weight: 130.0772

Fluorouracil

CAS: 51-21-8

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

• Formula: C₄H₃FN₂O₂
• Color and Shape: White Off-White Powder
• Molecular weight: 130.01786

5-Fluorouracil

CAS: 51-21-8

5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis.

• Formula: C₄H₃FN₂O₂
• Purity: 100% - 99.98%
• Color and Shape: White To Practically White Crystalline Powder Neoplastic Drug Chemosterilant For Insects (Epa 1998)
• Molecular weight: 130.08

5-Fluorouracil

CAS: 51-21-8

• Formula: C₄H₃FN₂O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 130.0772

5-Fluorouracil

CAS: 51-21-8

• Formula: C₄H₃FN₂O₂
• Purity: ≥ 99.0%
• Color and Shape: White to almost white crystalline powder
• Molecular weight: 130.08

5-Fluorouracil

CAS: 51-21-8

• Purity: 99%
• Molecular weight: 130.08g/mol

5-Fluorouracil

CAS: 51-21-8

• Formula: C₄H₃FN₂O₂
• Purity: 99%
• Color and Shape: white solid
• Molecular weight: 130.08g/mol

Fluorouracil-13C-15N2

CAS: 51-21-8

• Formula: C₃₁₃CH₃F₁₅N₂O₂
• Color and Shape: Pale Yellow Solid
• Molecular weight: 133.06

Fluorouracil

CAS: 51-21-8

• Formula: C₄H₃FN₂O₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 130.08

5-Fluorouracil, 99%

CAS: 51-21-8

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₄H₃FN₂O₂
• Purity: 99%
• Color and Shape: White to off-white, Crystalline powder
• Molecular weight: 130.08

Fluorouracil

CAS: 51-21-8

• Formula: C₄H₃FN₂O₂
• Color and Shape: White
• Molecular weight: 130.08

5-Fluorouracil

CAS: 51-21-8

• Formula: C₄H₃FN₂O₂
• Color and Shape: White
• Molecular weight: 130.08

5-Fluorouracil

CAS: 51-21-8

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 130.0780029296875

5-Fluorouracil

CAS: 51-21-8

• Formula: C₄H₃FN₂O₂
• Purity: 99.78% (lc-ms) (Typical Value in Batch COA)
• Color and Shape: white to off-white solid
• Molecular weight: 130.08g/mol

5-Fluoro Uracil

CAS: 51-21-8

Impurity Flucytosine EP Impurity A Applications 5-Fluoro Uracil is is an DNA/RNA synthesis inhibitor. It …

• Formula: C₄H₃FN₂O₂
• Color and Shape: White
• Molecular weight: 130.08

5-Fluorouracil - Bio-X ™

CAS: 51-21-8

5-Fluorouracil is a cytotoxic drug that inhibits the synthesis of DNA. It is used in …

• Formula: C₄H₃FN₂O₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 130.08 g/mol