CAS 56-75-7: (-)-Chloramphenicol

Description: (-)-Chloramphenicol, with the CAS number 56-75-7, is a broad-spectrum antibiotic originally derived from the bacterium Streptomyces venezuelae. It is characterized by its ability to inhibit bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome, effectively blocking peptide bond formation. This compound is a white to off-white crystalline powder that is soluble in water and alcohol but has limited solubility in organic solvents. Its molecular formula is C11H12Cl2N2O5, and it has a molecular weight of approximately 323.13 g/mol. (-)-Chloramphenicol exhibits antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. However, its use is limited due to potential side effects, including aplastic anemia and gray baby syndrome in newborns. As a result, it is often reserved for serious infections where other antibiotics are ineffective. Proper handling and dosage are crucial to minimize adverse effects and ensure therapeutic efficacy.

Formula: C₁₁H₁₂Cl₂N₂O₅

InChI: InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1

InChI key: InChIKey=WIIZWVCIJKGZOK-RKDXNWHRSA-N

SMILES: O=C(NC(CO)C(O)C1=CC=C(C=C1)N(=O)=O)C(Cl)Cl

Synonyms:

• 2,2-Dichloro-N-(2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl)-Acetamid
• 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• 2,2-Dichloro-N-[2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide
• 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• 2,2-dichloro-N-[(1R,2S)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• 2,2-dichloro-N-[(1S,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• Ak-Chlor
• Alficetyn
• Amphenicol
• Amphicol
• Amseclor
• Anacetin
• Aquamycetin
• Austracol
• Bradyoxetin
• CAF
• CAM
• CAP
• CPh
• Catilan
• Chemicetin
• Chemicetina
• Chlomycol
• Chloramex
• Chloramphenicol
• Chloramsaar
• Chlorasol
• Chlorcetin
• Chloricol
• Chlorocaps
• Chlorocid
• Chlorocide
• Chlorocin
• Chloromycetin
• Chloronitrin
• Chloroptic
• Ciplamycetin
• Cloramfen
• Cloramfenicol
• Cloramficin
• Cloramicol
• Clorocyn
• Cloromisan
• Cylphenicol
• D-(-)-Chloramphenicol
• D-(-)-Threo-2,2-Dichloro-N-[Beta-Hydroxy-Alpha-(Hydroxy-Methyl)-P-Nitrophenethyl]Acetamide
• D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol
• D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol
• D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol
• D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol
• D-(-)-threo-Chloramphenicol
• D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol
• D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
• Detreomycin
• Embacetin
• Enicol
• Enteromycetin
• Farmicetina
• Fenicol
• Globenicol
• Gloveticol
• Halcetin
• Intramycetin
• Ismicetina
• Juvamycetin
• Kamaver
• Kemicetine
• Klorita
• Leukomyan
• Leukomycin
• Levocin
• Levomicetina
• Levomitsetin
• Levomycetin
• Levoplast
• Levosin
• Levovetin
• Loromisin
• Mastiphen
• Micloretin
• Micoclorina
• Microcetina
• Mychel
• Mychel-Vet
• Mycinol
• Myclocin
• Mycochlorin
• Novomycetin
• Ocuphenicol
• Opclor
• Ophthochlor
• Pantovernil
• Paraxin
• Quemicetina
• Ronphenil
• Septicol
• Sintomicetin
• Sintomicetina
• Soluthor
• Stanomycetin
• Synthomycetin
• Synthomycin
• Tevcocin
• Tifomycine
• Treomicetina
• Unimycetin
• Veticol
• Viceton
• [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• D,L-chloramphenicol
• Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-
• nitrophenyl)ethyl]acetamide
• Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
• 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-

Chloramphenicol

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: >99%
• Color and Shape: solid
• Molecular weight: 323.13g/mol

Chloramphenicol, USP grade

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: 97.0 - 103.0 %
• Color and Shape: White to light-yellow crystalline powder
• Molecular weight: 323.14

Chloramphenicol

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Molecular weight: 323.13

Chloramphenicol (10mg/ml)

CAS: 56-75-7

• Color and Shape: Solution
• Molecular weight: 323.13g/mol

Chloramphenicol-d5 (100Mug/mL in Acetonitrile)

CAS: 56-75-7

• Formula: C₁₁H₇D₅Cl₂N₂O₅
• Color and Shape: Colourless
• Molecular weight: 328.16

Chloramphenicol

CAS: 56-75-7

Applications Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has …

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Color and Shape: White To Light Yellow
• Molecular weight: 323.13

Chloramphenicol-d5

CAS: 56-75-7

Applications Chloramphenicol-d5, is the labeled analogue of Chloramphenicol (C325030), which has a broad spectrum of …

• Formula: C₁₁H₇D₅Cl₂N₂O₅
• Color and Shape: Off-White
• Molecular weight: 328.16

Chloramphenicol

CAS: 56-75-7

Chloramphenicol is produced by Streptomyces venezuelae. It is a broad-spectrum antibiotic with bacteriostatic properties. It …

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 323.13 g/mol

Chloramphenicol (CFP), 98-102%

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: min. 98-102%
• Color and Shape: White to pale yellow, Crystalline powder, Clear
• Molecular weight: 323.1

Chloramphenicol (CFP) for tissue culture, 98-102%

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: 98 - 102%
• Color and Shape: White to pale yellow, Crystalline powder, Clear
• Molecular weight: 323.1