CAS 56390-09-1: Epirubicin hydrochloride

Description: Epirubicin hydrochloride is an anthracycline antibiotic and a chemotherapeutic agent primarily used in the treatment of various cancers, including breast cancer and other solid tumors. It is a derivative of doxorubicin, characterized by its ability to intercalate DNA, thereby inhibiting DNA and RNA synthesis, which ultimately leads to cell death. The substance appears as a red to reddish-brown powder and is soluble in water, which facilitates its administration via intravenous injection. Epirubicin hydrochloride has a molecular formula that reflects its complex structure, which includes multiple aromatic rings and hydroxyl groups that contribute to its biological activity. Its mechanism of action involves the generation of free radicals and the disruption of topoisomerase II activity, further enhancing its efficacy against rapidly dividing cancer cells. While effective, it is associated with potential side effects, including cardiotoxicity, myelosuppression, and gastrointestinal disturbances, necessitating careful monitoring during treatment. Overall, epirubicin hydrochloride remains a vital component in oncological therapies, demonstrating significant antitumor activity.

Formula: C₂₇H₂₉NO₁₁·ClH

InChI: InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22-,27-;/m0./s1

InChI key: InChIKey=MWWSFMDVAYGXBV-FGBSZODSSA-N

SMILES: Cl.O=C1C=2C=CC=C(OC)C2C(=O)C=3C(O)=C4C(=C(O)C13)CC(O)(C(=O)CO)CC4OC5OC(C)C(O)C(N)C5

Synonyms:

• (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranoside hydrochloride (1:1)
• (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-beta-L-arabino-hexopyranoside
• 4′-Epidoxorubicin hydrochloride
• 4′-epi-Adriamycin hydrochloride
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, hydrochloride (1:1), (8S,10S)-
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S,10S)-
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)-
• Ellence
• Epidoxorubicin hydrochloride
• Epirubicin Hydrochloride
• Farmorubicin
• L-Erythro-Dihydrosphingosine
• Pharmorubicin
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, hydrochloride (1:1), (8S,10S)-
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)-
• 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S,10S)-

Epirubicin Hydrochloride

CAS: 56390-09-1

• Formula: C₂₇H₂₉NO₁₁·HCl
• Purity: >95.0%(HPLC)
• Color and Shape: Light yellow to Yellow to Orange powder to crystal
• Molecular weight: 579.98

Epirubicin hydrochloride

CAS: 56390-09-1

Cell-permeable anthracycline anti-tumor antibiotic This Thermo Scientific Chemicals brand product was originally part of the …

• Formula: C₂₇H₂₉NO₁₁•HCl
• Molecular weight: 579.98

EPIRUBICIN HYDROCHLORIDE

CAS: 56390-09-1

• Purity: 95%
• Molecular weight: 579.97998046875

Epirubicin hydrochloride

CAS: 56390-09-1

• Formula: C₂₇H₂₉NO₁₁HCl
• Purity: 96.0%
• Color and Shape: Red
• Molecular weight: 579.15074

Epirubicin hydrochloride CRS

CAS: 56390-09-1

• Formula: C₂₇H₃₀ClNO₁₁
• Color and Shape: Orange. Red. Powder.
• Molecular weight: 579.9802

Epirubicin Hydrochloride

CAS: 56390-09-1

Antibiotics nesoi

• Formula: C₂₇H₂₉NO₁₁·ClH
• Color and Shape: Red Powder
• Molecular weight: 579.15074

Epirubicin hydrochloride

CAS: 56390-09-1

Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective …

• Formula: C₂₇H₃₀ClNO₁₁
• Purity: 98.13% - 99.79%
• Color and Shape: Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)
• Molecular weight: 579.98

5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, hydrochloride (1:1), (8S,10S)-

CAS: 56390-09-1

• Formula: C₂₇H₃₀ClNO₁₁
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 579.9802

Epirubicin hydrochloride

CAS: 56390-09-1

• Purity: ≥98%
• Molecular weight: 579.98g/mol

Epirubicin hydrochloride

CAS: 56390-09-1

• Formula: C₂₇H₂₉NO₁₁·HCl
• Purity: 97.0 - 102.0 % (dried basis)
• Color and Shape: Red to orange crystalline powder
• Molecular weight: 579.98

Epirubicin HCl (epi-Doxorubicin HCl)

CAS: 56390-09-1

• Formula: C₂₇H₂₉NO₁₁·HCl
• Molecular weight: 543.53 36.46

Epirubicin hydrochloride

CAS: 56390-09-1

• Formula: C₂₇H₂₉NO₁₁·ClH
• Purity: 99.99% (Typical Value in Batch COA)
• Color and Shape: red solid
• Molecular weight: 579.98g/mol

Epirubicin Hydrochloride

CAS: 56390-09-1

• Formula: C₂₇H₂₉NO₁₁·ClH
• Color and Shape: Neat
• Molecular weight: 579.98

Doxorubicin Impurity 38

CAS: 56390-09-1

• Formula: C₂₇H₂₇NO₁₀
• Molecular weight: 525.51

Epirubicin Hydrochloride RS

CAS: 56390-09-1

• Color and Shape: Pale Yellowish Red To Brownish Red Solid Powder

Epirubicin Hydrochloride

CAS: 56390-09-1

Applications Used as an antineoplastic. References Kolaric, K., et al.: J. Cancer Res. Clin. Oncol., …

• Formula: C₂₇H₂₉NO₁₁·ClH
• Color and Shape: Red
• Molecular weight: 579.98

Epirubicin hydrochloride

CAS: 56390-09-1

Topoisomerase II and DNA helicase inhibitor

• Formula: C₂₇H₃₀ClNO₁₁
• Purity: Min. 95%
• Color and Shape: Powder

Epirubicin Hydrochloride (EPR.HCl), 97%

CAS: 56390-09-1

• Formula: C₂₇H₂₉NO₁₁·HCl
• Molecular weight: 579.98

epi-Doxorubicin HCl

CAS: 56390-09-1

• Formula: C₂₇H₂₉NO₁₁·HCl
• Molecular weight: 543.53 36.46

Epirubicin hydrochloride

CAS: 56390-09-1

• Formula: C₂₇H₂₉NO₁₁·ClH
• Color and Shape: Neat
• Molecular weight: 579.98