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CAS 633-65-8

:

Berberine hydrochloride

Description:
Berberine hydrochloride is a quaternary ammonium salt derived from the alkaloid berberine, which is found in various plants, including goldenseal and barberry. It is characterized by its bright yellow color and is known for its bitter taste. The substance is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. Berberine hydrochloride exhibits a range of biological activities, including antimicrobial, anti-inflammatory, and antidiabetic properties, which have garnered interest in both traditional and modern medicine. Its mechanism of action involves the modulation of several cellular pathways, including those related to glucose metabolism and lipid regulation. Additionally, berberine has been studied for its potential effects on cardiovascular health and gut microbiota. Due to its diverse pharmacological effects, berberine hydrochloride is often used in dietary supplements and herbal remedies, although its use should be approached with caution due to potential interactions with other medications and side effects. Overall, berberine hydrochloride is a compound of significant interest in both research and therapeutic contexts.
Formula:C20H18ClNO4
InChI:InChI=1/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;
InChI key:InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M
SMILES:O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1OC.[Cl-]
Synonyms:
  • 1,3-Benzodioxolo[5,6-A]Benzo[G]Quinolizinium, 5,6-Dihydro-9,10-Dimethoxy-, Hydrochloride (1:1)
  • 16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride
  • Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
  • Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1)
  • Berberberberine hydrochloride n-hydrate
  • Berberine IR
  • Berberine chloride
  • Berberine hcl
  • Berberinium chloride
  • Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride
  • See more synonyms
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Found 19 products.
  • Berberine Chloride Hydrate

    CAS:
    Formula:C20H18ClNO4·xH2O
    Purity:>98.0%(T)(HPLC)
    Color and Shape:White to Yellow to Orange powder to crystaline
    Molecular weight:371.82 (as Anhydrous)

    Ref: 3B-B0450

    5g
    22.00€
    25g
    61.00€
  • Berberine chloride

    CAS:
    <p>Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical r</p>
    Formula:C20H18ClNO4
    Color and Shape:Yellow to orange, Powder
    Molecular weight:371.82

    Ref: 02-J62311

    5g
    49.00€
  • Berberine chloride

    CAS:
    Berberine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.
    Formula:C20H18ClNO4
    Purity:(HPLC) ≥95%
    Color and Shape:Powder
    Molecular weight:371.82

    Ref: 11-0601

    100mg
    57.00€
  • BERBERINE CHLORIDE CRS

    CAS:
    BERBERINE CHLORIDE CRS
    Formula:C20H19ClNO4
    Molecular weight:372.8216

    Ref: 41-Y0001149

    20mg
    115.00€
  • Berberine chloride

    CAS:
    Berberine chloride
    Formula:C20H18NO4
    Purity:77.7%
    Color and Shape:White
    Molecular weight:336.12358

    Ref: 47-1108

    100mg
    242.00€
  • Berberine chloride

    CAS:
    Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.
    Formula:C20H18ClNO4
    Purity:99.47% - 99.93%
    Color and Shape:Yellow Crystalline Powder
    Molecular weight:371.80
  • Berberine hydrochloride

    CAS:
    Formula:C20H18ClNO4
    Purity:97%
    Color and Shape:Solid
    Molecular weight:371.8142

    Ref: IN-DA00IB6S

    5g
    30.00€
    10g
    34.00€
    25g
    51.00€
    100g
    129.00€
    500g
    519.00€
  • Berberine chloride

    CAS:
    Berberine chloride
    Purity:≥98%
    Molecular weight:371.8g/mol

    Ref: 54-BUP19732

    5g
    52.00€
  • Berberine hydrochloride

    CAS:
    Berberine hydrochloride
    Purity:98%
    Molecular weight:371.81g/mol

    Ref: 54-OR1028076

    25g
    36.00€
    100g
    102.00€
    500g
    334.00€
    2.5kg
    1,378.00€
  • Berberine hydrochloride

    CAS:
    Formula:C20H18ClNO4
    Purity:96.0 - 104.0 % (dried basis)
    Color and Shape:Yellow or orange powder
    Molecular weight:371.82

    Ref: 7W-GK8292

    5g
    38.00€
    10g
    63.00€
  • Berberine hydrochloride

    CAS:
    Berberine hydrochloride (berberine), a natural plant alkaloid derived from Chinese herbal medicine, is characterized by diverse pharmacological effects, such as anticancer and lower elevated blood glucose, it can prevent adhesion by downregulating ICAM-1 and reduce inflammation by inhibiting the TAK1/JNK and TAK1/NF-κB signaling after abdominal surgery, which brings out a good therapeutic approach for the development of clinical application for postoperative abdominal adhesion and inflammation.
    Formula:C20H18ClNO4
    Purity:95%~99%
    Color and Shape:Powder
    Molecular weight:371.817

    Ref: BP-BP0252

    20mg
    48.00€
    1000mg
    88.00€
  • Berberine Chloride

    Controlled Product
    CAS:
    Formula:C20H18NO4·Cl
    Color and Shape:Neat
    Molecular weight:371.81

    Ref: 86-MM1632.00

    250mg
    163.00€
  • Berberine chloride

    Controlled Product
    CAS:
    Formula:C20H18NO4·Cl
    Color and Shape:Neat
    Molecular weight:371.81

    Ref: 04-C10573950

    100mg
    109.00€
  • Berberine Hydrochloride-d6

    Controlled Product
    CAS:
    <p>Stability Hygroscopic<br>Applications Berberine Hydrochloride-d6 is labelled Berberine Hydrochloride (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells<br>References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);<br></p>
    Formula:C20H12D6ClNO4
    Color and Shape:Neat
    Molecular weight:377.85

    Ref: TR-B318152

    1mg
    348.00€
    10mg
    2,382.00€
  • Berberine Chloride Hydrate

    Controlled Product
    CAS:
    <p>Stability Hygroscopic<br>Applications An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.<br>References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);<br></p>
    Formula:C20H18NO4·Cl
    Color and Shape:Light Yellow To Yellow
    Molecular weight:371.81

    Ref: TR-B318150

    10g
    90.00€
    25g
    175.00€
    100g
    484.00€
  • Berberine hydrochloride

    CAS:
    Formula:C20H18ClNO4
    Purity:95.0%
    Color and Shape:Solid
    Molecular weight:371.82

    Ref: 10-F516404

    10g
    23.00€
    25g
    38.00€
    100g
    110.00€
    500g
    462.00€
  • Berberine Chloride

    CAS:
    Formula:C20H18NO4Cl
    Molecular weight:336.4 : 35.5

    Ref: ST-EA-CP-B118001

    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Berberine chloride

    CAS:
    Activates AMPK enzyme; anti-inflammatory; anti-diabetic
    Formula:C20H18NO4•Cl
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:371.81 g/mol

    Ref: 3D-FB64955

    5g
    203.00€
    10g
    363.00€
    1kg
    To inquire
    25g
    724.00€
    50g
    1,288.00€
  • Berberine Chloride

    CAS:
    Color and Shape:Neat

    Ref: 61-FOR1632.00

    10mg
    Discontinued
    Discontinued product