CAS 64924-67-0: Halofuginone hydrobromide
Description:Halofuginone hydrobromide is a synthetic compound primarily recognized for its use in veterinary medicine, particularly as an anti-coccidial agent. It is derived from the natural alkaloid fuginone, which is obtained from the plant species *Fusarium* and exhibits a range of biological activities. The hydrobromide salt form enhances its solubility and stability, making it suitable for pharmaceutical applications. Halofuginone hydrobromide is characterized by its ability to inhibit collagen synthesis, which has implications in various therapeutic areas, including fibrosis and inflammation. The compound typically appears as a crystalline solid and is soluble in water and organic solvents. Its mechanism of action involves the modulation of signaling pathways related to cell proliferation and differentiation. Safety and efficacy profiles are critical for its use, and it is subject to regulatory scrutiny in veterinary and potentially human applications. As with any chemical substance, proper handling and adherence to safety guidelines are essential to mitigate any risks associated with its use.
Formula:C16H17BrClN3O3·BrH
InChI:InChI=1/C16H17BrClN3O3.BrH/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;/h5-6,8,14-15,19,23H,1-4,7H2;1H/t14-,15+;/s2
InChI key:InChIKey=SJUWEPZBTXEUMU-AJYMSAGVNA-N
SMILES:Br.O=C1C=2C=C(Cl)C(Br)=CC2N=CN1CC(=O)CC3NCCCC3O
- Synonyms:
- 4(3H)-Quinazolinone, 7-bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-, monohydrobromide, trans-
- 4(3H)-Quinazolinone, 7-bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-, hydrobromide (1:1), rel-
- 4(3H)-Quinazolinone, 7-bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-, monohydrobromide, rel-
- 7-Bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one hydrobromide
- 7-bromo-6-chloro-3-{3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one hydrobromide
- Ru 19110
- Stenorol
