CAS 66-81-9: (-)-Cycloheximide

Description: (-)-Cycloheximide is a naturally occurring compound that serves as an important inhibitor of protein synthesis in eukaryotic cells. It is derived from the bacterium Streptomyces griseus and is primarily used in research to study gene expression and protein function. The substance is characterized by its ability to inhibit the elongation phase of translation by interfering with the ribosomal machinery, specifically targeting the 60S ribosomal subunit. This inhibition leads to a decrease in the synthesis of proteins, making it a valuable tool in molecular biology and biochemistry. (-)-Cycloheximide is typically a white to off-white crystalline powder, and it is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), but has limited solubility in water. Due to its potent biological activity, it is important to handle (-)-Cycloheximide with care, as it can be toxic to cells and may pose health risks if not managed properly in laboratory settings.

Formula: C₁₅H₂₃NO₄

InChI: InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1

InChI key: InChIKey=YPHMISFOHDHNIV-FSZOTQKASA-N

SMILES: O=C1NC(=O)CC(C1)CC(O)C2C(=O)C(C)CC(C)C2

Synonyms:

• 2,6-Piperidinedione
• 2,6-Piperidinedione, 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-
• 2,6-Piperidinedione, 4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-, [1S-[1α(S*),3α,5β]]-
• 3-(2-(3,5-Dimethyl-2-Oxocyclohexyl)-2-Hydroxyethyl)Glutarimide
• 3-[2-(3,5-Dimethyl-2-oxo-1-cyclohexyl)-2-hydroxyethyl]glutarimide
• 4-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)
• 4-[(2R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-2,6-piperidinedione
• 4-[2-(3,5-Dimethyl-2-Oxocyclohexyl)-2-Hydroxyethyl]Piperidine-2,6-Dione
• 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione
• Acti-Aid
• Acti-dione
• Acti-dione BR
• Acti-dione PM
• Acti-dione TGF
• Actidion
• Actidione
• Cicloheximid
• Cicloheximida
• Cicloheximide
• Cycloheximid
• Ft 3422-2
• Glutarimide, 3-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-
• Ldn 97549
• Naramycin
• Naramycin A
• Naramycin Microcapsule D 80
• Naramycin NM-MCU 80
• Nm-Mcd 80
• Nsc 185
• TZA
• U 4527
• l-Cycloheximide
• β-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide

Cycloheximide solution, 100mg/mL in DMSO, 0.2 micron filtered

CAS: 66-81-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. …

• Formula: C₁₅H₂₃NO₄
• Molecular weight: 281.35

Cycloheximide, 90%

CAS: 66-81-9

A frequently used lab reagent that inhibits fungal growth by targeting protein synthesis. This Thermo …

• Formula: C₁₅H₂₃NO₄
• Purity: 90%
• Color and Shape: White to pale cream, Powder or crystals or crystalline powder
• Molecular weight: 281.35

Cycloheximide, ultrapure, 95%

CAS: 66-81-9

A protein synthesis inhibitor in eukaryotic cells This Thermo Scientific Chemicals brand product was originally …

• Formula: C₁₅H₂₃NO₄
• Purity: 95%
• Color and Shape: White to cream, Powder
• Molecular weight: 281.35

Cycloheximide; Actidione; Acti-Aid; Naramycin; Naramycin-A; NSC-185; A-67; Zygomycin-D

CAS: 66-81-9

• Formula: C₁₅H₂₃NO₄
• Purity: 96.74%
• Color and Shape: Yellowish. Oily solid
• Molecular weight: 281.0

3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide

CAS: 66-81-9

• Formula: C₁₅H₂₃NO₄
• Purity: By hplc: 94.1% (Typical Value in Batch COA)
• Color and Shape: off-white powder
• Molecular weight: 281.35g/mol

Cycloheximide

CAS: 66-81-9

• Formula: C₁₅H₂₃NO₄
• Purity: ≥ 98.0% (HPLC)
• Color and Shape: White or off-white crystalline powder
• Molecular weight: 281.35

Cycloheximide

CAS: 66-81-9

• Purity: 99%
• Molecular weight: 281.35g/mol

Cycloheximide

CAS: 66-81-9

Cycloheximide (Naramycin A) is an antimitotic compound and an inhibitor of DNA and protein synthesis.

• Formula: C₁₅H₂₃NO₄
• Purity: 95.08% - 99.95%
• Color and Shape: Liquid
• Molecular weight: 281.35

LC PestiMix 6 10 µg/mL in Acetonitrile

CAS: 1007-28-9 1114-71-2 113036-88-7 113136-77-9 114420-56-3 115086-54-9 115852-48-7 116255-48-2 119791-41-2 121776-33-8 126535-15-7 130000-40-7 136849-15-5 138164-12-2 139528-85-1 147150-35-4 149508-90-7 180409-60-3 181274-17-9 1929-88-0 199119-58-9 2008-41-5 210631-68-8 211867-47-9 221667-31-8 223580-51-6 23576-24-1 239110-15-7 2439-10-3 25606-41-1 27314-13-2 27605-76-1 2797-51-5 302-27-2 321-54-0 32889-48-8 3337-71-1 335104-84-2 33820-53-0 35367-31-8 37019-18-4 372137-35-4 4151-50-2 422556-08-9 42609-52-9 4849-32-5 55861-78-4 57160-47-1 58011-68-0 6119-70-6 61432-55-1 64-10-8 66-81-969335-91-7 69806-50-4 74051-80-2 74222-97-2 76578-12-6 8065-36-9 81103-11-9 81335-77-5 82211-24-3 838-85-7 86811-58-7 88678-67-5 90982-32-4 91-22-5 93697-74-6 944-22-9 951659-40-8 96182-53-5 96525-23-4 97780-06-8 97886-45-8 99105-77-8

• Color and Shape: Mixture

Cycloheximide, 95%

CAS: 66-81-9

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₅H₂₃NO₄
• Purity: 95%
• Color and Shape: White to light beige, Powder
• Molecular weight: 281.35

Cycloheximide

CAS: 66-81-9

• Formula: C₁₅H₂₃NO₄
• Color and Shape: Neat
• Molecular weight: 281.35

Cycloheximide 100 µg/mL in Acetonitrile

CAS: 66-81-9

• Formula: C₁₅H₂₃NO₄
• Color and Shape: Single Solution
• Molecular weight: 281.35

Cycloheximide

CAS: 66-81-9

Applications Cycloheximide is an antibiotic substance isolated from the beers of streptomycin-producing strains of Streptomyces …

• Formula: C₁₅H₂₃NO₄
• Color and Shape: Colourless
• Molecular weight: 281.35

Cycloheximide - Antibiotic for Culture Media Use Only

CAS: 66-81-9

Cycloheximide is produced by the bacteria Streptomyces griseus. In eukaryotic organisms, it acts as an …

• Formula: C₁₅H₂₃NO₄
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 281.35 g/mol

Cycloheximide, Antibiotic for Culture Media Use Only

CAS: 66-81-9

Please enquire for more information about Cycloheximide, Antibiotic for Culture Media Use Only including the …

• Formula: C₁₅H₂₃NO₄
• Molecular weight: 281.35 g/mol

Cycloheximide

CAS: 66-81-9

Cycloheximide is produced by the bacteria Streptomyces griseus. In eukaryotic organisms, it acts as an …

• Formula: C₁₅H₂₃NO₄
• Purity: Min. 90%
• Color and Shape: White Powder
• Molecular weight: 281.35 g/mol

Cycloheximide for tissue culture, 94%

CAS: 66-81-9

• Formula: C₁₅H₂₃NO₄
• Purity: min. 94%
• Color and Shape: White to off - white, Crystalline powder
• Molecular weight: 281.35

Cycloheximide extrapure, 94%

CAS: 66-81-9

• Formula: C₁₅H₂₃NO₄
• Purity: min, 94%
• Color and Shape: White to off - white, Crystalline powder
• Molecular weight: 281.35