CAS 116255-48-2
:Bromuconazole
Description:
Bromuconazole is a chemical compound classified as a triazole fungicide, primarily used in agricultural applications to control a variety of fungal diseases in crops. Its structure features a bromine atom, which contributes to its biological activity, and a triazole ring that is characteristic of many fungicides. Bromuconazole acts by inhibiting the biosynthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting fungal growth and reproduction. The compound is typically applied as a foliar spray and is known for its systemic properties, allowing it to be absorbed by plants and provide protection against pathogens. In terms of physical properties, bromuconazole is generally characterized by its moderate solubility in organic solvents and low volatility, which aids in its effectiveness as a pesticide. Safety assessments indicate that, like many agrochemicals, it should be handled with care to minimize environmental impact and ensure human safety. Its use is regulated in many regions, and it is important to follow guidelines for application and safety measures.
Formula:C13H12BrCl2N3O
InChI:InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2
InChI key:InChIKey=HJJVPARKXDDIQD-UHFFFAOYSA-N
SMILES:C(C1(CC(Br)CO1)C2=C(Cl)C=C(Cl)C=C2)N3C=NC=N3
Synonyms:- 1-((2RS,4RS,2RS,4SR)-4-Bromo-2-(2,4-dichlorophenyl) tetrahydrofurfuryl)-1H-1,2,4-triazole
- 1-((2Rs,4Rs,2Rs,4Sr)-4-Bromo-2-(2,4-Dichlorophenyl)Tetrahydrofurfuryl)-1H-1,
- 1-((4-Bromo-2-(2,4-Dichlorophenyl)Tetrahydro-2-Furanyl)Methyl)-1H-1,2,4-Tria
- 1H-1,2,4-Triazole, 1-[[4-bromo-2-(2,4-dichlorophenyl)tetrahydro-2-furanyl]methyl]-
- 1H-1,2,4-Triazole,1-((4-Bromo-2-(2,4-Dichlorophenyl)Tetrahydro-2-Furanyl)Methy
- 2,5-Anhydro-4-bromo-1,3,4-trideoxy-2-C-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol
- 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol
- Bromoconazole
- Bromuconazol
- Granit
- Granit (pesticide)
- Ls 860263
- Pentitol, 2,5-anhydro-4-bromo-1,3,4-trideoxy-2-C-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)-
- Vectra
- See more synonyms
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LC PestiMix 6 10 µg/mL in Acetonitrile
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Color and Shape:MixtureGC PestiMix 3 10 µg/mL in Isooctane:Toluene (50:50)
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Color and Shape:MixtureBromuconazole
CAS:Controlled ProductFormula:C13H12BrCl2N3OColor and Shape:NeatMolecular weight:377.06Bromuconazole 10 µg/mL in Cyclohexane
CAS:Controlled ProductFormula:C13H12BrCl2N3OColor and Shape:Single SolutionMolecular weight:377.06Bromuconazole
CAS:Controlled ProductFormula:C13H12BrCl2N3OColor and Shape:NeatMolecular weight:377.06Bromuconazole
CAS:Formula:C13H12BrCl2N3OColor and Shape:COLOURLESS CRYSTALS OR WHITE POWDER.Molecular weight:377.1Bromuconazole in Acetonitrile
CAS:AcetonitrileFormula:C13H12BrCl2N3OColor and Shape:COLOURLESS CRYSTALS OR WHITE POWDER.Molecular weight:377.1Bromuconazole
CAS:Bromuconazole is a systemic fungicide, which is a synthetic chemical compound primarily used to protect crops from fungal diseases. It is derived from the triazole class of fungicides, which are known for their ability to inhibit important biochemical processes within fungal cells. The mode of action of Bromuconazole involves the inhibition of the enzyme C14-demethylase, a key component in the biosynthesis of ergosterol. Ergosterol is an essential component of fungal cell membranes, and its disruption leads to impaired cellular function and ultimately the death of the fungal organism.
Formula:C13H12BrCl2N3OPurity:Min. 95%Molecular weight:377.1 g/molBromuconazole
CAS:Bromuconazole is a triazole fungicide with oral efficacy and blood-brain barrier permeability. It offers protection to crops against various fungal contaminations. Bromuconazole is cytotoxic to multiple cancer cells, inducing G0/G1 phase cell cycle arrest and inhibiting DNA synthesis. It disrupts cytoskeletal structures, causes genotoxic damage, induces apoptosis, and leads to mitochondrial membrane depolarization. Bromuconazole activates caspase-3, triggers the excessive production of ROS, p53, and Bax, promotes lipid peroxidation, and increases the activity of SOD and CAT while downregulating Bcl-2. By upregulating p-ERK1/2 and p-JNK, it disrupts the MAPK signaling pathway, impairing the endometrial and trophoblast cell stress responses, which hinders implantation. Bromuconazole is used in research related to glioma, colon cancer, reproductive damage (implantation dysfunction), and cardiac dysfunction.Formula:C13H12BrCl2N3OMolecular weight:377.06





