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CAS 68-35-9

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Sulfadiazine

Description:
Sulfadiazine is a sulfonamide antibiotic characterized by its broad-spectrum antibacterial properties. It is a white to off-white crystalline powder that is soluble in water and has a melting point typically around 165-170°C. The chemical formula for sulfadiazine is C10H10N4O2S, and it features a sulfonamide group, which is essential for its antibacterial activity. Sulfadiazine works by inhibiting bacterial synthesis of folic acid, thereby interfering with their growth and reproduction. It is commonly used in veterinary medicine and can also be applied in human medicine for treating certain infections. The substance is generally well-absorbed when administered orally and is metabolized in the liver. However, it can cause side effects such as allergic reactions, gastrointestinal disturbances, and, in rare cases, more severe reactions like Stevens-Johnson syndrome. Due to its potential for resistance development, sulfadiazine is often used in combination with other antibiotics to enhance its efficacy. Proper dosage and monitoring are essential to minimize adverse effects and ensure therapeutic effectiveness.
Formula:C10H10N4O2S
InChI:InChI=1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14)
InChI key:InChIKey=SEEPANYCNGTZFQ-UHFFFAOYSA-N
SMILES:S(NC=1N=CC=CN1)(=O)(=O)C2=CC=C(N)C=C2
Synonyms:
  • 2-(4-Aminobenzenesulfonamido)pyrimidine
  • 2-(4-Aminobenzenesulfonylamino)pyrimidine
  • 2-(p-Aminobenzenesulfonamido)pyrimidin
  • 2-Sulfanilamidopyrimidine
  • 2-Sulfanilylaminopyrimidine
  • 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide
  • 4-Amino-N-(2-pyrimidyl)benzenesulfonamide
  • 4-Amino-N-2-pyrimidinylbenzenesulfonamide
  • 4-[[(Pyrimidin-2-yl)amino]sulfonyl]aniline
  • A 306
  • See more synonyms
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