CAS 69-23-8

Fluphenazine

Description:

Fluphenazine is a typical antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the phenothiazine class of drugs and functions as a dopamine D2 receptor antagonist, which helps to alleviate symptoms of psychosis by modulating neurotransmitter activity in the brain. The substance is characterized by its relatively high potency and long duration of action, often administered in both oral and injectable forms. Fluphenazine is known for its potential side effects, which may include extrapyramidal symptoms, sedation, and metabolic changes. It is important to monitor patients for these effects during treatment. The chemical structure of fluphenazine includes a trifluoromethyl group, contributing to its pharmacological properties. Additionally, it is classified as a controlled substance in some jurisdictions due to its potential for misuse. Overall, fluphenazine remains a significant option in psychiatric care, particularly for managing chronic conditions requiring long-term treatment.

Formula: C₂₂H₂₆F₃N₃OS

InChI: InChI=1/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2

InChI key: InChIKey=PLDUPXSUYLZYBN-UHFFFAOYSA-N

SMILES: C(CCN1CCN(CCO)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(C(F)(F)F)C3

Synonyms:

• 1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine
• 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-
• 10-[3-(2-Hydroxyethyl)piperazinopropyl]-2-(trifluoromethyl)phenothiazine
• 2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanol
• 2-Trifluoromethyl-10-(3-[4-(β-hydroxyethyl)piperazinyl]-propyl)-phenothiazine
• 2-[4-[3-(2-Trifluoromethyl-phenothiazin-10-yl)-propyl]-piperazin-1-yl]-ethanol
• 4-[3-(2-Trifluoromethyl-10-phenothiazyl)-propyl]-1-piperazineethanol
• 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol
• 4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazine ethanol
• Elinol
• Flufenazina
• Fluorfenazine
• Fluorophenazine
• Fluorphenazine
• Fluphenazin
• Fluphenazine
• Ftorphenazine
• Pacinol
• Phthorphenazine
• S 94
• Siqualine
• Siqualon
• Sq 4918
• Triflumethazine
• Vespazine
• Modecate
• Permitil
• Prolixin
• 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-
• Kitasamycin
• FLUPHENAZINE USP/EP/BP
• moditen(tablorelixir)
• Fluphenazine Hydrochloride
• sq4918
• phenothiazine,10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl-2-(trifluoromethy
• Phenothiazine, 10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-2-(trifluoromethyl)-
• dapotum
• 4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol
• Fluphenazine HydrochlorideQ: What is
• Prolixine
• Yespazine
• 2-(4-(3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol
• Fluphenazine Decaonate
• 10-(3’-(4"-(beta-hydroxyethyl)-1"-piperazinyl)-propyl)-3-trifluoromethylphenot
• Fluphenazine Hydrochloride Q: What is the CAS Number of
• Fluphenazine Decanoate Impurity 2
• kitasamycin，leucomycin
• phenothiazine,10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-2-(trifluorome
• FLUFENAZINE
• hiazine
• Fluphenazine free base
• 69-23-8
• 4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-1-piperazineethano
• Fluphenazine Decanoate EP Impurity B
• Fluphenazine dihydrochloride solution
• 2-(trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-piperazinyl)propyl)phenothi
• Sevinol
• s94

Fluphenazine free base

CAS: 69-23-8

Flufenazine: antipsychotic for schizophrenia, blocks dopamine D2 receptors, reduces hallucinations and delusions.

Formula: C₂₂H₂₆F₃N₃OS

Color and Shape: Solid

Molecular weight: 437.52

Ref: TM-T0068L2

Fluphenazine

CAS: 69-23-8

Fluphenazine

Purity: 98%

Molecular weight: 437.52g/mol

Ref: 54-PC111396

GB 31660.1-2019 Macrolide Antibiotics Mixture 167 100 µg/mL in Methanol

Controlled Product

CAS: 114-07-8, 1401-69-0, 16846-24-5, 2751-09-9, 69-23-8, 8025-81-8, 81103-11-9, 83905-01-5, 93952-07-9

Color and Shape: Mixture

Ref: 04-A50000167ME

Fluphenazine

Controlled Product

CAS: 69-23-8

Applications Fluphenazine is a dopamine receptor antagonist.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Charles, I., et al.: Analytical Proceedings, 22, 135 (1985)

Formula: C₂₂H₂₆N₃OSF₃diHCl

Color and Shape: Neat

Molecular weight: 510.44

Ref: TR-F598418

Fluphenazine Decanoate EP Impurity B

CAS: 69-23-8

Formula: C₂₂H₂₆F₃N₃OS

Molecular weight: 437.53

Ref: ST-EA-CP-F65002

FLUPHENAZINE

CAS: 69-23-8

Formula: C₂₂H₂₆F₃N₃OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 437.5215

Ref: IN-DA005KIL

Fluphenazine

Controlled Product

CAS: 69-23-8

Fluphenazine is an antipsychotic drug that belongs to the phenothiazine class of drugs and is used in the treatment of schizophrenia. Fluphenazine has a low rate constant for protein binding and can be used as a probe for drug interactions. The serum prolactin levels were significantly increased in the low-dose group, but not in the high-dose group. Fluphenazine is metabolized through glucuronidation or oxidation by alcohol dehydrogenase to inactive metabolites. It also acts as an antagonist at multidrug efflux pumps, which may explain its effectiveness against treatment-resistant schizophrenia.

Formula: C₂₂H₂₆F₃N₃OS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 437.52 g/mol

Ref: 3D-FF102008