CAS 76-05-1: Trifluoroacetic acid

Description: Trifluoroacetic acid (TFA) is a colorless, pungent liquid with the chemical formula C2HF3O2. It is a strong organic acid, characterized by the presence of three fluorine atoms attached to the carbon backbone, which significantly enhances its acidity compared to acetic acid. TFA is highly soluble in water and many organic solvents, making it a versatile reagent in various chemical reactions. Its strong acidity is utilized in organic synthesis, particularly in the preparation of trifluoroacetyl derivatives and as a catalyst in certain reactions. TFA is also known for its ability to stabilize carbanions and is commonly used in peptide synthesis and protein chemistry. However, it is important to handle TFA with care, as it is corrosive and can cause severe burns upon contact with skin. Additionally, TFA is considered environmentally persistent, and its use is regulated in some regions due to potential ecological impacts. Overall, trifluoroacetic acid is a valuable compound in both industrial and laboratory settings, owing to its unique chemical properties.

Formula: C₂HF₃O₂

InChI: InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key: InChIKey=DTQVDTLACAAQTR-UHFFFAOYSA-N

SMILES: O=C(O)C(F)(F)F

Synonyms:

• 2,2,2-Trifluoroacetic acid
• Acetic acid, 2,2,2-trifluoro-
• Acetic acid, trifluoro-
• Aceticacid, trifluoro-
• Acide trifluoroacetique
• Acido Trifluoroacetico
• Chlorinated Paraffin-52
• Kyselina trifluoroctova
• Kyselinatrifluoroctova
• Nsc 77366
• Perfluoroacetic acid
• Perfluoroaceticacid
• TFA
• Trifluoracetic acid
• Trifluoraceticacid
• Trifluoressigsaeure
• Trifluoressigsaure
• Trifluoressigs~ure
• Trifluoro-Aceticacid
• Trifluoroacetetic Acid
• Trifluoroaceticacidmincolorlessliq
• Trifluoroethanoic acid
• Trifluoroethanoicacid
• Trifluoroacetic acid
• Aceticacid, 2,2,2-trifluoro-

Trifluoroacetic Acid (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS]

CAS: 76-05-1

• Formula: C₂HF₃O₂
• Color and Shape: Colorless clear liquid
• Molecular weight: 114.02

Trifluoroacetic Acid [Sequenation Reagent]

CAS: 76-05-1

• Formula: C₂HF₃O₂
• Purity: >99.0%(T)
• Color and Shape: Colorless clear liquid
• Molecular weight: 114.02

Trifluoroacetic acid, 99%

CAS: 76-05-1

The combination of properties like solubility in most of the solvents, volatility, catalytic property, and …

• Formula: C₂HF₃O₂
• Purity: 99%
• Color and Shape: Clear colorless to pale yellow, Fuming liquid
• Molecular weight: 114.02

Trifluoroacetic acid, biochemical grade, 99.5+%

CAS: 76-05-1

Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the …

• Formula: C₂HF₃O₂
• Purity: 99.5+%
• Color and Shape: Liquid, Clear colorless
• Molecular weight: 114.02

Trifluoroacetic acid, 99%

CAS: 76-05-1

The combination of properties like solubility in most of the solvents, volatility, catalytic property, and …

• Formula: C₂HF₃O₂
• Purity: 99%
• Color and Shape: Clear colorless to pale yellow or pale pink, Fuming liquid
• Molecular weight: 114.02

Trifluoroacetic acid, HPLC Grade, 99.5+%

CAS: 76-05-1

The combination of properties like solubility in most of the solvents, volatility, catalytic property and …

• Formula: C₂HF₃O₂
• Purity: 99.5+%
• Color and Shape: Liquid, Clear colorless
• Molecular weight: 114.02

Trifluoroacetic acid, 99.5+%

CAS: 76-05-1

The combination of properties like solubility in most of the solvents, volatility, catalytic property and …

• Formula: C₂HF₃O₂
• Purity: 99.5+%
• Color and Shape: Clear colorless, Liquid
• Molecular weight: 114.02

Trifluoroacetic acid, 99%

CAS: 76-05-1

• Formula: CF₃COOH
• Purity: 99%
• Color and Shape: colorless liq.
• Molecular weight: 114.02

Trifluoroacetic acid

CAS: 76-05-1

• Formula: CF₃CO₂H
• Purity: (Titration) ≥ 99.0%
• Color and Shape: Clear, colourless to faint yellow liquid
• Molecular weight: 114.02

Trifluoroacetic acid

CAS: 76-05-1

• Formula: C₂HF₃O₂
• Purity: 99.5%
• Color and Shape: clear. colourless liquid
• Molecular weight: 114.02g/mol

Trifluoroacetic acid

CAS: 76-05-1

• Formula: C₂HF₃O₂
• Purity: biochemical grade 99.9%
• Color and Shape: clear liquid
• Molecular weight: 114.02g/mol

Trifluoroacetic acid

CAS: 76-05-1

• Formula: C₂HF₃O₂
• Purity: 99.5%
• Color and Shape: clear. colourless liquid
• Molecular weight: 114.02g/mol

Trifluoroacetic acid, 99+%, for spectroscopy

CAS: 76-05-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂HF₃O₂
• Purity: 99+%
• Color and Shape: Clear colorless, Liquid
• Molecular weight: 114.02

Trifluoroacetic Acid

CAS: 76-05-1

• Formula: C₂HF₃O₂
• Purity: >99.0%(T)
• Color and Shape: Colorless to Almost colorless clear liquid
• Molecular weight: 114.02

Trifluoroacetic acid, 99.5%, for biochemistry

CAS: 76-05-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂HF₃O₂
• Purity: 99.5%
• Color and Shape: Clear liquid
• Molecular weight: 114.02

Trifluoroacetic acid

CAS: 76-05-1

• Formula: C₂HF₃O₂
• Color and Shape: Neat
• Molecular weight: 114.02

Trifluoroacetic acid 50 µg/mL in Methanol:Water

CAS: 76-05-1

• Color and Shape: Single Solution

Ultrashort-chain-PFAS (C1-C4) Mixture 50 µg/mL in Methanol:Water

CAS: 1493-13-6 354-88-1 375-22-4 375-73-5 422-64-0 423-41-6 76-05-1

• Color and Shape: Mixture

Trifluoroacetic acid, 99+%, for HPLC

CAS: 76-05-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂HF₃O₂
• Purity: 99+%
• Color and Shape: Clear liquid
• Molecular weight: 114.02

Trifluoroacetic acid, 99+%, extra pure

CAS: 76-05-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂HF₃O₂
• Purity: 99+%
• Color and Shape: Clear liquid
• Molecular weight: 114.02