CAS 76-05-1
:Trifluoroacetic acid
Description:
Trifluoroacetic acid (TFA) is a colorless, pungent liquid with the chemical formula C2HF3O2. It is a strong organic acid, characterized by the presence of three fluorine atoms attached to the carbon backbone, which significantly enhances its acidity compared to acetic acid. TFA is highly soluble in water and many organic solvents, making it a versatile reagent in various chemical reactions. Its strong acidity is utilized in organic synthesis, particularly in the preparation of trifluoroacetyl derivatives and as a catalyst in certain reactions. TFA is also known for its ability to stabilize carbanions and is commonly used in peptide synthesis and protein chemistry. However, it is important to handle TFA with care, as it is corrosive and can cause severe burns upon contact with skin. Additionally, TFA is considered environmentally persistent, and its use is regulated in some regions due to potential ecological impacts. Overall, trifluoroacetic acid is a valuable compound in both industrial and laboratory settings, owing to its unique chemical properties.
Formula:C2HF3O2
InChI:InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
InChI key:InChIKey=DTQVDTLACAAQTR-UHFFFAOYSA-N
SMILES:C(C(O)=O)(F)(F)F
Synonyms:- 2,2,2-Trifluoroacetic acid
- Acetic acid, 2,2,2-trifluoro-
- Acetic acid, trifluoro-
- Aceticacid, trifluoro-
- Acide trifluoroacetique
- Acido Trifluoroacetico
- Chlorinated Paraffin-52
- Kyselina trifluoroctova
- Kyselinatrifluoroctova
- Nsc 77366
- Perfluoroacetic acid
- Perfluoroaceticacid
- TFA
- Trifluoracetic acid
- Trifluoraceticacid
- Trifluoressigsaeure
- Trifluoressigsaure
- Trifluoressigs~ure
- Trifluoro-Aceticacid
- Trifluoroacetetic Acid
- Trifluoroaceticacidmincolorlessliq
- Trifluoroethanoic acid
- Trifluoroethanoicacid
- Trifluoroacetic acid
- See more synonyms
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Trifluoroacetic Acid
CAS:Formula:C2HF3O2Purity:>99.0%(T)Color and Shape:Colorless to Almost colorless clear liquidMolecular weight:114.02Trifluoroacetic Acid [Sequenation Reagent]
CAS:Formula:C2HF3O2Purity:>99.0%(T)Color and Shape:Colorless clear liquidMolecular weight:114.02Trifluoroacetic Acid (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS]
CAS:Formula:C2HF3O2Color and Shape:Colorless clear liquidMolecular weight:114.02Trifluoroacetic acid, 99%
CAS:The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemiFormula:C2HF3O2Purity:99%Color and Shape:Clear colorless to pale yellow or pale pink, Fuming liquidMolecular weight:114.02Trifluoroacetic acid, HPLC Grade, 99.5+%
CAS:The combination of properties like solubility in most of the solvents, volatility, catalytic property and strong acidity with non-oxidizing nature makes it a widely used reagent in an organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrocheFormula:C2HF3O2Purity:99.5+%Color and Shape:Liquid, Clear colorlessMolecular weight:114.02Trifluoroacetic acid, biochemical grade, 99.5+%
CAS:Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the sFormula:C2HF3O2Purity:99.5+%Color and Shape:Liquid, Clear colorlessMolecular weight:114.02Trifluoroacetic acid, 99.5+%
CAS:The combination of properties like solubility in most of the solvents, volatility, catalytic property and strong acidity with non-oxidizing nature makes it a widely used reagent in an organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrocheFormula:C2HF3O2Purity:99.5+%Color and Shape:Clear colorless, LiquidMolecular weight:114.02Trifluoroacetic acid, 99%
CAS:Solvent, catalyst, strong non-oxidizing acidFormula:C2HF3O2Purity:99%Color and Shape:Clear colorless to pale yellow, Fuming liquidMolecular weight:114.02Trifluoroacetic acid
CAS:Trifluoroacetic acidFormula:C2HF3O2Purity:biochemical grade 99.9%Color and Shape:Colourless LiquidMolecular weight:114.02334Trifluoroacetic acid
CAS:Trifluoroacetic acidFormula:C2HF3O2Purity:99.5%Color and Shape:Colourless LiquidMolecular weight:114.02334Trifluoroacetic acid
CAS:Trifluoroacetic acidFormula:C2HF3O2Purity:biochemical grade 99.9%Color and Shape:Colourless LiquidMolecular weight:114.02334Trifluoroacetic acid
CAS:Formula:CF3CO2HPurity:(Titration) ≥ 99.0%Color and Shape:Clear, colourless to faint yellow liquidMolecular weight:114.02Trifluoroacetic acid
CAS:Trifluoroacetic acidFormula:C2HF3O2Purity:99.5%Color and Shape:LiquidMolecular weight:114.02334Trifluoroacetic acid
CAS:Controlled ProductFormula:C2HF3O2Color and Shape:NeatMolecular weight:114.02Tigecycline (open C-ring D-ring) Quinone Trifluoroacetic Acid Salt
CAS:Controlled ProductApplications Tigecycline (open C-ring D-ring) quinone Trifluoroacetic Acid Salt is a salt of Tigecycline (open C-ring D-ring) quinone, an impurity of Tigecycline (T440015). Tigecycline (open C-ring D-ring) quinone is one of the very few glycylcycline antimicrobials that exhibit activity against Gram-negative bacteria and also one of the few that also circumvent around the major resistance mechanisms of tetracycline.
References Grosse, E., et al.: Clin. Infect. Dis. (Supplement 5), 41, S341 (2005); Livermore, D.: J. Antimicrob. Chemoth., 56, 611 (2005); Stein, G. & Craig, W.: Clin. Infect. Dis., 43, 518 (2006)Formula:C26H32N4O8•x(C2HF3O2)Color and Shape:NeatMolecular weight:642.6
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