CAS 82419-36-1: Ofloxacin

Description: Ofloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections, including those affecting the respiratory tract, urinary tract, and skin. The chemical structure of ofloxacin includes a bicyclic core with a fluorine atom, which enhances its potency and spectrum of activity against Gram-positive and Gram-negative bacteria. It exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and repair. Ofloxacin is typically administered orally or intravenously and is known for its good bioavailability. It is also important to note that, like other fluoroquinolones, ofloxacin may have side effects, including gastrointestinal disturbances and potential effects on tendons. Its use is generally contraindicated in certain populations, such as pregnant women and children, due to concerns about cartilage development. Overall, ofloxacin remains a valuable option in the antibiotic arsenal, particularly for infections resistant to other treatments.

Formula: C₁₈H₂₀FN₃O₄

InChI: InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)

InChI key: InChIKey=GSDSWSVVBLHKDQ-UHFFFAOYSA-N

SMILES: O=C(O)C1=CN2C3=C(OCC2C)C(=C(F)C=C3C1=O)N4CCN(C)CC4

Synonyms:

• (+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
• (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazin-yl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
• (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• (S)-(-)-Ofloxacin
• (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
• 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-
• 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• 9-Fluoro-2,3-dihydro-3-methyl-10-(N-methylpiperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• 9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• Dl 8280
• Exocin
• Flobacin
• Floxal
• Floxil
• Floxin
• Floxin Otic
• Gailuoxian
• Hoe 280
• Kirol
• Levaquin
• Levofloxacin
• Levofloxacino
• Levofloxacinum
• Meneflox
• Ocuflox
• Oflicin
• Oflin
• Oflocet
• Oflocin
• Ofloren
• Oflovir
• Oflox
• Ofloxacin Otic
• Ofloxacin S-(-)-form
• Ofloxacina
• Ofloxacine
• Ofloxacino
• Ofloxacinum
• Ofloxin
• Oflx
• Ofxin
• Olfo 200
• Oquin
• Orf 18489
• Otoxin
• Oxaldin
• Prifloxcin
• Prifloxin
• Pt 01
• Sanke
• Surnor
• Tariferid
• Tarivan
• Tarivid
• Traflox
• Visiren
• Visren
• Wp 0405
• Zanocin
• Zenflox
• (-)-Ofloxacin

Ofloxacin

CAS: 82419-36-1

Fluorinated nalidixic acid analog with broad-spectrum antibacterial activity This Thermo Scientific Chemicals brand product was …

• Formula: C₁₈H₂₀FN₃O₄
• Color and Shape: White to off-white, Powder
• Molecular weight: 361.37

Ofloxacin CRS

CAS: 82419-36-1

• Formula: C₁₈H₂₀FN₃O₄
• Molecular weight: 361.3675

Ofloxacin

CAS: 82419-36-1

• Formula: C₁₈H₂₀FN₃O₄
• Purity: 99.3%
• Color and Shape: Off-White
• Molecular weight: 361.14378

Ofloxacin

CAS: 82419-36-1

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₁₈H₂₀FN₃O₄
• Color and Shape: Off-White Pale Yellow Powder
• Molecular weight: 361.14378

Ofloxacin

CAS: 82419-36-1

• Formula: C₁₈H₂₀FN₃O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 361.3675

Ofloxacin

CAS: 82419-36-1

Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic.

• Formula: C₁₈H₂₀FN₃O₄
• Purity: 99.33% - 99.87%
• Color and Shape: Off-White Solid
• Molecular weight: 361.37

Ofloxacin

CAS: 82419-36-1

• Purity: ≥98%
• Molecular weight: 361.37g/mol

Ofloxacin

CAS: 82419-36-1

• Molecular weight: 361.37g/mol

Ofloxacin

CAS: 82419-36-1

• Formula: C₁₈H₂₀FN₃O₄
• Purity: ≤ 0.3%
• Color and Shape: White to light-yellow crystalline powder
• Molecular weight: 361.37

Ofloxacin

CAS: 82419-36-1

• Formula: C₁₈H₂₀FN₃O₄
• Color and Shape: Neat
• Molecular weight: 361.37

Ofloxacin, 98%

CAS: 82419-36-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₈H₂₀FN₃O₄
• Purity: 98%
• Color and Shape: Powder, White to yellow
• Molecular weight: 361.37

Ofloxacin

CAS: 82419-36-1

• Formula: C₁₈H₂₀FN₃O₄
• Color and Shape: Neat
• Molecular weight: 361.37

Ofloxacin 100 µg/mL in Acetonitrile

CAS: 82419-36-1

• Formula: C₁₈H₂₀FN₃O₄
• Color and Shape: Single Solution
• Molecular weight: 361.37

PharmaVetResiMix 3 Quinolones-v18 10 µg/mL in Methanol

CAS: 115550-35-1 119478-55-6 14698-29-4 149676-40-4 19562-30-2 28657-80-9 389-08-2 42835-25-6 51940-44-4 70458-96-7 74011-58-8 79660-72-3 82419-36-185721-33-1 91296-86-5 91296-87-6 93106-60-6 98079-52-8

• Color and Shape: Mixture

GB/T 21312-2007 14 Quinolones 20 µg/mL in Methanol

CAS: 112398-08-0 14698-29-4 28657-80-9 389-08-2 42835-25-6 51940-44-4 70458-92-3 70458-96-7 74011-58-8 82419-36-185721-33-1 91296-87-6 93106-60-6 98079-52-8

• Color and Shape: Mixture

Ministry of Agriculture Veterinary Drug Mixture 348 10 µg/mL in Acetonitrile:Water

CAS: 102-65-8 112398-08-0 115550-35-1 122-11-2 1220-83-3 127-69-5 127-71-9 127-79-7 144-80-9 144-83-2 23282-55-5 2447-57-6 2462-17-1 526-08-9 57-67-0 59-40-5 63-74-1 68-35-9 70458-92-3 723-46-6 738-70-5 82419-36-191296-86-5 93106-60-6 98079-51-7

• Color and Shape: Mixture

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3 113507-06-5 115550-35-1 117704-25-3 119478-55-6 122-11-2 1220-83-3 123997-26-2 127-71-9 127-79-7 144-82-1 144-83-2 14698-29-4 148-79-8 149676-40-4 155569-91-8 19562-30-2 20559-55-1 2447-57-6 28657-80-9 31430-15-6 31431-39-7 389-08-2 42835-25-6 43210-67-9 515-64-0 51940-44-4 53716-50-0 54029-12-8 54965-21-8 57-67-0 57-68-1 58306-30-2 59-40-5 63-74-1 651-06-9 68-35-9 68786-66-3 70288-86-7 70458-96-7 71751-41-2 72-14-0 723-46-6 729-99-7 74011-58-8 75184-71-3 79660-72-3 80-08-0 80-32-0 80-35-3 80983-34-2 82419-36-185721-33-1 88254-99-3 91296-86-5 91296-87-6 93106-60-6 948-71-0 98079-52-8

• Color and Shape: Mixture

Ofloxacin

CAS: 82419-36-1

• Formula: C₁₈H₂₀FN₃O₄
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 361.37

Ofloxacin

CAS: 82419-36-1

• Formula: C₁₈H₂₀FN₃O₄
• Molecular weight: 361.37

Ofloxacin

CAS: 82419-36-1

Applications Ofloxacin is a fluorinated quinolone antibacterial.This compound is a contaminant of emerging concern (CECs). …

• Formula: C₁₈H₂₀FN₃O₄
• Color and Shape: Off-White
• Molecular weight: 361.37