CAS 86386-73-4
:Fluconazole
Description:
Fluconazole is an antifungal medication primarily used to treat fungal infections, particularly those caused by Candida species and Cryptococcus neoformans. It belongs to the triazole class of antifungals and works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and function. Fluconazole is characterized by its high oral bioavailability, allowing for effective systemic treatment, and it is often administered in both oral and intravenous forms. The substance is generally well-tolerated, with common side effects including gastrointestinal disturbances and headache. It has a relatively long half-life, enabling once-daily dosing for many indications. Fluconazole is also notable for its ability to penetrate various body tissues, including the central nervous system, making it effective for treating meningitis. However, it can interact with other medications due to its effects on liver enzymes, necessitating careful monitoring in patients on multiple therapies. Overall, fluconazole is a critical agent in the management of systemic and superficial fungal infections.
Formula:C13H12F2N6O
InChI:InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2
InChI key:InChIKey=RFHAOTPXVQNOHP-UHFFFAOYSA-N
SMILES:C(CN1C=NC=N1)(CN2C=NC=N2)(O)C3=C(F)C=C(F)C=C3
Synonyms:- 1-(2,4-Difluorophenyl)-1,1-bis[(1H-1,2,4-triazol-1-yl)methyl]methanol
- 1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-
- 2-(2,4-Difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)-propan-2-ol
- 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
- Alkanazole
- Biozolene
- Diflucan
- Difluconazole
- Elazor
- Floroxan
- Flucan
- Fluconal
- Flucostat
- Flumycon
- Flunazol
- Flusol
- Flutec
- Fluzon
- Fungican
- Fungicon
- Triconal
- Triflucan
- Uk 49858
- Zocon
- Zoltec
- a.-(2,4-Difluorophenyl)-a-(1H-1,2,4,-triazol-1-ylmethyl)-1H-1,2 ,4-triazole-1-ethanol
- α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol
- See more synonyms
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Fluconazole
CAS:Formula:C13H12F2N6OPurity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:306.28Fluconazole, 99%
CAS:<p>Fluconazole, 86386-73-4, is a synthetic triazole, demethylase, and a cytochrome P-450 inhibitor with antifungal activity against some Candida infections. Learn more.</p>Formula:C13H12F2N6OPurity:99%Color and Shape:White to pale cream, PowderMolecular weight:306.28Fluconazole
CAS:FluconazoleFormula:C13H12F2N6OPurity:99.4%Color and Shape:White. To. Off-WhiteMolecular weight:306.10407FLUCONAZOLE CRS
CAS:<p>FLUCONAZOLE CRS</p>Formula:C13H12F2N6OColor and Shape:Crystalline Powder. White. Powder.Molecular weight:306.2708FLUCONAZOLE FOR PEAK IDENTIFICATION CRS
CAS:<p>FLUCONAZOLE FOR PEAK IDENTIFICATION CRS</p>Formula:C13H12F2N6OMolecular weight:306.2708Fluconazole
CAS:<p>Anti-infective agents, nesoi</p>Formula:C13H12F2N6OColor and Shape:White Off-White PowderMolecular weight:306.104071H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-
CAS:Formula:C13H12F2N6OPurity:98%Color and Shape:SolidMolecular weight:306.2708Ref: IN-DA000KX6
5g27.00€10g42.00€1kg586.00€25g72.00€2kgTo inquire5kgTo inquire100g163.00€500g647.00€Fluconazole
CAS:<p>Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.</p>Formula:C13H12F2N6OPurity:98.57% - 99.17%Color and Shape:White Or Off White Crystalline PowderMolecular weight:306.27Fluconazole
CAS:Formula:C13H12F2N6OPurity:(non-aqueous titration) ≥ 98.5% (dried basis)Color and Shape:White to almost white powder or crystalsMolecular weight:306.27Fluconazole (anhydrous)
CAS:Fluconazole (anhydrous)Formula:C13H12F2N6OPurity:98%Color and Shape: white solidMolecular weight:306.27078g/molFluconazole-d4 (bismethylene-d4) (
CAS:Purity:98 atom % DColor and Shape:White To Off-White SolidMolecular weight:310.30Fluconazole 100 µg/mL in Acetonitrile
CAS:Formula:C13H12F2N6OColor and Shape:Single SolutionMolecular weight:306.27Fluconazole
CAS:<p>Applications Fluconazole is used as an antifungal.<br>References Richard, K. et al.: Antimicrob. Ag. Chemother., 27, 832 (1985),<br></p>Formula:C13H12F2N6OColor and Shape:NeatMolecular weight:306.27Fluconazole - Bio-X ™
CAS:<p>Fluconazole is an antifungal drug used to treat a wide range of fungal infections. Fluconazole is a cytochrome demethylase system inhibitor that acts by interfering with β-glucan biosynthesis. It has been shown to be effective in treating candidemia, a life-threatening form of candidiasis caused by the fungus Candida albicans. Fluconazole seems to be more effective than amphotericin B in treating some isolates of C. albicans, making it a valuable tool in the fight against this deadly fungal infection, although due to the increase of antimicrobial resistance, fluconazole has been studied in combination with other drugs (e.g. farnesol).</p>Formula:C13H12F2N6OPurity:(%) Min. 95%Color and Shape:PowderMolecular weight:306.27 g/mol
