CAS 89786-04-9
:Tazobactam
Description:
Tazobactam is a β-lactamase inhibitor commonly used in combination with certain antibiotics to enhance their efficacy against resistant bacterial strains. It is a white to off-white crystalline powder that is soluble in water and exhibits a molecular formula of C10H12N4O4S. Tazobactam works by inhibiting the activity of β-lactamase enzymes produced by bacteria, which are responsible for breaking down β-lactam antibiotics, thus allowing these antibiotics to remain effective. The compound is often used in clinical settings alongside piperacillin, forming a combination that broadens the spectrum of activity against various Gram-negative and some Gram-positive bacteria. Tazobactam has a relatively low toxicity profile, making it suitable for use in patients with infections caused by resistant organisms. Its pharmacokinetics involve rapid absorption and distribution, with renal excretion being the primary route of elimination. Overall, Tazobactam plays a crucial role in combating antibiotic resistance and improving treatment outcomes for bacterial infections.
Formula:C10H12N4O5S
InChI:InChI=1/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1
InChI key:InChIKey=LPQZKKCYTLCDGQ-WEDXCCLWSA-N
SMILES:C([C@@]1(C)[C@H](C(O)=O)N2[C@](S1(=O)=O)(CC2=O)[H])N3C=CN=N3
Synonyms:- (2S,3S)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
- (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
- 1H-1,2,3-Triazole, 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid deriv.
- 2B-[(1,2,3-Triazol-1-Yl)Methyl]-2A-Methylpenam-3A-Carboxylic Acid 1,1-Dioxide
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S,3S,5R)-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, [2S-(2α,3β,5α)]-
- Cl 298741
- Tazobactam acid
- Ytr 830H
- Tazobactam
- (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid
- (2S,3S,5R)-2-Carboxy-3-methyl-3-[(1H-1,2,3-triazol-1-yl)methyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane4,4-dioxide
- 4,4-dioxide,(2s-(2-alpha,3-beta,5-alpha))--triazol-1-ylmethyl)
- cl298741
- ytr83oh
- TAZOBACTAN ACID
- Tazobactam,Tazobactanacid
- [2S-(2α,3β,5α)]-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
- CL-298741:YTR-830
- Tazobactum (Free acid)
- See more synonyms
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Found 19 products.
Tazobactam
CAS:Formula:C10H12N4O5SPurity:>97.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:300.29Tazobactam, 94%
CAS:<p>Tazobactam, 94%</p>Formula:C10H12N4O5SPurity:94%Color and Shape:White to off-white, Powder or crystals or crystalline powderMolecular weight:300.29Tazobactam
CAS:Penicillins and their derivatives with a penicillanic acid structure and salts thereof, nesoiFormula:C10H12N4O5SColor and Shape:White Pale Yellow PowderMolecular weight:300.05284(2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CAS:Formula:C10H12N4O5SPurity:98%Color and Shape:SolidMolecular weight:300.2911Tazobactam
CAS:<p>Tazobactam (YTR-830H) is an antibacterial penicillin derivative which inhibits the action of bacterial beta-lactamases.</p>Formula:C10H12N4O5SPurity:99.53%Color and Shape:White To Off-White Solid PowderMolecular weight:300.29Tazobactam
CAS:Formula:C10H12N4O5SPurity:98.0 - 102.0 % (anhydrous basis)Color and Shape:White to off-white crystalline powderMolecular weight:300.29PharmaVetResiMix 6 Betalactams-v23 0.2-2.5 µg/mL in Water:Acetonitrile
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Color and Shape:MixtureTazobactam Sodium Salt-15N3
CAS:Formula:C10H11N15N3NaO5SColor and Shape:White To Off-WhiteMolecular weight:325.25Ref: 10-F041178
1gTo inquire5gTo inquire10gTo inquire25gTo inquire100gTo inquire100mgTo inquire250mgTo inquireTazobactam
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications Tazobactam is a β-Lactamase inhibitor, used with β-lactam antibiotics to enhance their effect.<br>References Gould, I.M., et al.: Drugs Exp. Clin. Res., 17, 187 (1991), Roland, R.K., et al.: J. Infect. Dis., 4, 226 (2000), Bonomo, R.A., et al.: Biochim. Biophys. Acta, 1547, 196 (2001),<br></p>Formula:C10H12N4O5SColor and Shape:Off-WhiteMolecular weight:300.29Tazobactam
CAS:<p>Inhibitor of beta-lactamase; inhibitor of cell wall synthesis; beta-lactam class</p>Formula:C10H12N4O5SPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:300.29 g/mol
















