CAS 96020-91-6

Ornithine, 2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1)

Description:

Ornithine, 2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1) is a chemical compound characterized by its unique structure, which includes a difluoromethyl group attached to the ornithine backbone. This compound is a derivative of ornithine, an amino acid that plays a crucial role in the urea cycle and is involved in various metabolic processes. The presence of the difluoromethyl group may impart specific biological activities or enhance the compound's stability and solubility. As a hydrochloride salt, it is typically more soluble in water, making it suitable for various applications in biochemical research and pharmaceutical formulations. The hydrate form indicates the presence of water molecules in the crystal structure, which can affect the compound's physical properties, such as melting point and hygroscopicity. Overall, this compound's characteristics make it of interest in medicinal chemistry and related fields, where modifications to amino acids can lead to novel therapeutic agents.

Formula: C₆H₁₂F₂N₂O₂·ClH·H₂O

InChI: InChI=1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9;;/h4H,1-3,9-10H2,(H,11,12);1H;1H2

InChI key: InChIKey=FJPAMFNRCFEGSD-UHFFFAOYSA-N

SMILES: C(CCCN)(C(F)F)(C(O)=O)N.Cl.O

Synonyms:

• 2,5-Diamino-2-(Difluoromethyl)Pentanoic Acid
• 2,5-Diamino-2-(difluoromethyl)pentanoic acid hydrate hydrochloride
• <span class="text-smallcaps">DL</span>-Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate
• DFMO Eflornithine
• DMFO HCl
• Eflornithine hydrochloride monohydrate
• H-alpha-Difluoro-Me-DL-Orn-OH.HCl.H2O
• Ornithine, 2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1)
• Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate
• DL-Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate
• Vaniqa

Eflornithine Hydrochloride Monohydrate

CAS: 96020-91-6

Formula: C₆H₁₂F₂N₂O₂·HCl·H₂O

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 236.65

Ref: 3B-E0947

Eflornithine hydrochloride hydrate

CAS: 96020-91-6

Formula: C₆H₁₅ClF₂N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 236.64

Ref: 10-F438180

H-α-Difluoro-Me-DL-Orn-OH · HCl · H₂O

CAS: 96020-91-6

α-Difluoromethylornithine is a suicide inhibitor of ornithine decarboxylase. Initially developed for cancer treatment, eflornithine was found to be very efficient against trypanosomiasis. The ornithine derivative also found use in cosmetics, eflornithine-containing creams allow to reduce excessive hair growth (hirsutism). CAS Number (net): 67037-37-0, (hydrochloride): 68278-23-9.

Formula: C₆H₁₂F₂N₂O₂·HCl·H₂O

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 236.65

Ref: 01-4030547

Eflornithine Hydrochloride

CAS: 96020-91-6

Amino-acids and their esters other than those containing more than one kind of oxygen function, excluding aromatic amino-acids, nesoi

Formula: C₆H₁₂F₂N₂O₂·HCl·H₂O

Color and Shape: White Powder

Molecular weight: 182.08668

Ref: 45-1234249

Eflornithine Hydrochloride Monohydrate

CAS: 96020-91-6

Eflornithine Hydrochloride Monohydrate

Formula: C₆H₁₅F₂N₂O₃Cl

Purity: >98%

Molecular weight: 236.65

Ref: 54-PC105332

Eflornithine hydrochloride hydrate

CAS: 96020-91-6

Eflornithine hydrochloride hydrate

Formula: C₆H₁₅ClF₂N₂O₃

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 236.64

Ref: 54-BUP16092

Ornithine,2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1)

CAS: 96020-91-6

Formula: C₆H₁₅ClF₂N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 236.6447

Ref: IN-DA005W0A

Eflornithine Hydrochloride Monohydrate

Controlled Product

CAS: 96020-91-6

Applications Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.
References Bacchi, C.J., et al.: Science, 210, 332 (1980); Haegele, K.D., et al.: Clin. Pharmacol. Ther., 30, 210 (1981); Meyskens, F.L., et al.: Clin. Cancer Res., 5, 945 (1999);

Formula: C₆H₁₂F₂N₂O₂·ClH·H₂O

Color and Shape: Neat

Molecular weight: 236.64

Ref: TR-E436000

Eflornithine hydrochloride hydrate

CAS: 96020-91-6

Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is an ornithine decarboxylase (ODC) inhibitor with antitumor activity. Cost-effective and quality-assured.

Formula: C₆H₁₅ClF₂N₂O₃

Purity: 99% - 99.92%

Color and Shape: White Solid

Molecular weight: 236.64

Ref: TM-T2593

Eflornithine HCl monohydrate

CAS: 96020-91-6

Inhibitor of ornithine decarboxylase

Formula: C₆H₁₂F₂N₂O₂·HCl·H₂O

Purity: (Hplc) Min. 98%

Color and Shape: White Off-White Powder

Molecular weight: 236.64 g/mol

Ref: 3D-FE11666

Eflornithine HCl hydrate

CAS: 96020-91-6

2,5-Diamino-2-(difluoromethyl)pentanoic acid hydrochloride hydrate

Formula: C₆H₁₅ClF₂N₂O₃

Purity: 98%

Molecular weight: 236.64

Ref: IN-DG212962

Eflornithine-d6 Hydrochloride Monohydrate

Controlled Product

CAS: 96020-91-6

Applications Labelled Eflornithine. Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.
References Bacchi, C.J., et al.: Science, 210, 332 (1980), Haegele, K.D., et al.: Clin. Pharmacol. Ther., 30, 210 (1981), Meyskens, F.L., et al.: Clin. Cancer Res., 5, 945 (1999),

Formula: C₆D₆H₆F₂N₂O₂·HCl·H₂O

Color and Shape: Neat

Molecular weight: 242.682

Ref: TR-E436002